Search Results - "CALBECKA, Malgorzata"

Comparison of Cladribine Plus Cyclophosphamide With Fludarabine Plus Cyclophosphamide As First-Line Therapy for Chronic Lymphocytic Leukemia: A Phase III Randomized Study by the Polish Adult Leukemia Group (PALG-CLL3 Study) by Robak, Tadeusz, Jamroziak, Krzysztof, Gora-Tybor, Joanna, Stella-Holowiecka, Beata, Konopka, Lech, Ceglarek, Bernadetta, Warzocha, Krzysztof, Seferynska, Ilona, Piszcz, Jaroslaw, Calbecka, Malgorzata, Kostyra, Aleksandra, Dwilewicz-Trojaczek, Jadwiga, Dmoszyñska, Anna, Zawilska, Krystyna, Hellmann, Andrzej, Zdunczyk, Andrzej, Potoczek, Stanislaw, Piotrowska, Magdalena, Lewandowski, Krzysztof, Blonski, Jerzy Z

“…PURPOSE Little is known about comparison of the activity of different purine nucleoside analogs in chronic lymphocytic leukemia (CLL). We conducted a…”
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The germline mutations of the CHEK2 gene are associated with an increased risk of polycythaemia vera by Janiszewska, Hanna, Bąk, Aneta, Hartwig, Martyna, Kuliszkiewicz‐Janus, Małgorzata, Całbecka, Małgorzata, Jaźwiec, Bożena, Kuliczkowski, Kazimierz, Haus, Olga

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A single weekly dose of imatinib is sufficient to induce and maintain remission of chronic eosinophilic leukaemia in FIP1L1‐PDGFRA‐expressing patients by Helbig, Grzegorz, Stella‐Hołowiecka, Beata, Majewski, Mirosław, Całbecka, Małgorzata, Gajkowska, Jolanta, Klimkiewicz, Ryszard, Moskwa, Andrzej, Grzegorczyk, Janina, Lewandowska, Monika, Hołowiecki, Jerzy

“…Summary Hypereosinophilic syndrome (HES) is defined as chronic, unexplained hypereosinophilia with organ involvement. A subset of HES patients presents an…”
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Durable remission after treatment with very low doses of imatinib for FIP1L1-PDGFRα-positive chronic eosinophilic leukaemia by Helbig, Grzegorz, Moskwa, Andrzej, Hus, Marek, Piszcz, Jarosław, Swiderska, Alina, Urbanowicz, Alina, Całbecka, Małgorzata, Seferyńska, Ilona, Raźny, Małgorzata, Rodzaj, Marek, Żuk, Ewa, Kyrcz-Krzemień, Sławomira

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CD38 Gene Polymorphisms Contribute to Genetic Susceptibility to B-Cell Chronic Lymphocytic Leukemia: Evidence from Two Case-Control Studies in Polish Caucasians by JAMROZIAK, Krzysztof, SZEMRAJ, Zofia, KOSTYRA, Aleksandra, CALBECKA, Malgorzata, WAWRZYNIAK, Ewa, MIROWSKI, Marek, KORDEK, Radzislaw, ROBAK, Tadeusz, GRZYBOWSKA-IZYDORCZYK, Olga, SZEMRAJ, Janusz, BIENIASZ, Magdalena, CEBULA, Barbara, GIANNOPULOS, Krzysztof, BALCERCZAK, Ewa, JESIONEK-KUPNICKA, Dorota, KOWAL, Malgorzata

“…Given the recent findings on the importance of CD38 signaling in the pathogenesis of B-cell chronic lymphocytic leukemia (B-CLL), we hypothesized that single…”
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Weekly imatinib dosage for chronic eosinophilic leukaemia expressing FIP1L1‐PDGFRA fusion transcript: extended follow‐up by Helbig, Grzegorz, Moskwa, Andrzej, Swiderska, Alina, Urbanowicz, Alina, Całbecka, Małgorzata, Gajkowska, Justyna, Zdziarska, Barbara, Brzeźniakiewicz, Katarzyna, Pogrzeba, Joanna, Krzemień, Sławomira

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Clinical characteristics of patients with chronic eosinophilic leukaemia (CEL) harbouring FIP1L1-PDGFRA fusion transcript-results of Polish multicentre study by Helbig, Grzegorz, Moskwa, Andrzej, Hus, Marek, Piszcz, Jarosław, Swiderska, Alina, Urbanowicz, Alina, Całbecka, Małgorzata, Gajkowska, Justyna, Seferyńska, Ilona, Hałasz, Magdalena, Woszczyk, Dariusz, Markiewicz, Miroslaw, Krzemień, Sławomira

“…A small subgroup of patients with hypereosinophilic syndrome (HES) demonstrates imatinib‐sensitive fusion transcript—the FIP1L1‐PDGFRA (F/P+). These cases are…”
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Immunogenicity of Influenza Vaccine in Patients with Hemato-Oncological Disorders by Brydak, Lidia B., Calbecka, Malgorzata

“…The aim of this study was to measure the production of antihemagglutinin and antineuramini-dase antibodies in patients with proliferative diseases of the…”
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Ropeginterferon alfa-2b versus standard therapy for polycythaemia vera (PROUD-PV and CONTINUATION-PV): a randomised, non-inferiority, phase 3 trial and its extension study by Gisslinger, Heinz, Klade, Christoph, Georgiev, Pencho, Krochmalczyk, Dorota, Gercheva-Kyuchukova, Liana, Egyed, Miklos, Rossiev, Viktor, Dulicek, Petr, Illes, Arpad, Pylypenko, Halyna, Sivcheva, Lylia, Mayer, Jiri, Yablokova, Vera, Krejcy, Kurt, Grohmann-Izay, Barbara, Hasselbalch, Hans C, Kralovics, Robert, Kiladjian, Jean-Jacques, Bauer, Franz, Berbec, Nicoleta, Besses Raebel, Carlos, Borbenyi, Zita, Bumbea, Horia, Buxhofer-Ausch, Veronika, Calbecka, Malgorzata, Cayssials-Caylus, Emilie, Cazzola, Mario, Cerna, Olga, Cucuianu, Andrei, Dima, Delia Monica, Forjan, Ernst, Gheorghita, Emanuil, Greil, Richard, Hatalova, Antonia, Hrubisko, Mikulas, Jakucs, Janos, Kaplan, Polina, Klymenko, Sergiy, Koschmieder, Steffen, Lazaroiu, Mihaela, Lysa, Tamila, Masliak, Zvenyslava, Masszi, Tamas, Mihaylov, Georgi, Myasnikov, Alexander, Platzbecker, Uwe, Puyade, Mathieu, Rey, Jerome, Roy, Lydia, Schwarz, Jiri, Skotnicki, Aleksander, Sokolova, Irina, Soroka-Wojtaszko, Maria, Starzak-Gwozdz, Jolanta, Stoeva, Vera, Torregrosa-Diaz, Jose Miguel, Vallova, Anna, Volodicheva, Elena, Warzocha, Krzysztof, Willenbacher, Ella, Wolf, Dominik

“…The PROUD-PV and CONTINUATION-PV trials aimed to compare the novel monopegylated interferon ropeginterferon alfa-2b with hydroxyurea, the standard therapy for…”
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Real-life comparison of severe vascular events and other non-hematological complications in patients with chronic myeloid leukemia undergoing second-line nilotinib or dasatinib treatment by Gora-Tybor, Joanna, Medras, Ewa, Calbecka, Malgorzata, Kolkowska-Leśniak, Agnieszka, Ponikowska-Szyba, Edyta, Robak, Tadeusz, Jamroziak, Krzysztof

“…We retrospectively analyzed the rates of significant non-hematological adverse events (AEs) in 105 patients with chronic myeloid leukemia (CML) treated with…”
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Real-Life Comparison Of Severe Vascular Events and Other Non-Hematological Complications In CML Patients Treated With Second Line Nilotinib Or Dasatinib by Gora-Tybor, Joanna, Medras, Ewa, Calbecka, Malgorzata, Kolkowska, Agnieszka, Ponikowska-Szyba, Edyta, Robak, Tadeusz, Jamroziak, Krzysztof

“…Despite very good long-term results of imatinib (IM) in chronic myeloid leukemia (CML) patients about 30% of them will need the new treatment option. For these…”
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Cladribine alone and in combination with cyclophosphamide or cyclophosphamide plus mitoxantrone in the treatment of progressive chronic lymphocytic leukemia: report of a prospective, multicenter, randomized trial of the Polish Adult Leukemia Group (PALG CLL2) by Robak, Tadeusz, Blonski, Jerzy Z., Gora-Tybor, Joanna, Jamroziak, Krzysztof, Dwilewicz-Trojaczek, Jadwiga, Tomaszewska, Agnieszka, Konopka, Lech, Ceglarek, Bernadetta, Dmoszynska, Anna, Kowal, Malgorzata, Kloczko, Janusz, Stella-Holowiecka, Beata, Sulek, Kazimierz, Calbecka, Malgorzata, Zawilska, Krystyna, Kuliczkowski, Kazimierz, Skotnicki, Aleksander B., Warzocha, Krzysztof, Kasznicki, Marek

“…In this prospective randomized trial, we compared the efficacy and toxicity of cladribine (2-CdA) alone to 2-CdA combined with cyclophosphamide (CC) or…”
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Cladribine added to daunorubicin-cytarabine induction prolongs survival of FLT3-ITD+ normal karyotype AML patients by Libura, Marta, Giebel, Sebastian, Piatkowska-Jakubas, Beata, Pawelczyk, Marta, Florek, Izabella, Matiakowska, Karolina, Jazwiec, Bozena, Borg, Katarzyna, Solarska, Iwona, Zawada, Magdalena, Czekalska, Sylwia, Libura, Jolanta, Jakobczyk, Malgorzata, Karabin, Karolina, Paluszewska, Monika, Calbecka, Malgorzata, Gajkowska-Kulik, Justyna, Gadomska, Grazyna, Kielbinski, Marek, Ejduk, Anna, Kata, Dariusz, Grosicki, Sebastian, Wierzbowska, Agnieszka, Kyrcz-Krzemien, Slawomira, Warzocha, Krzysztof, Kuliczkowski, Kazimierz, Skotnicki, Aleksander, Holowiecki, Jerzy, Jedrzejczak, Wieslaw Wiktor, Haus, Olga

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Impact of Drug Transporters ABCB1 and ABCG2 and Regulators of Xenobiotic Transport and Metabolism Pxr and CAR Gene Polymorphisms on Clinical Efficacy of Imatinib in Chronic Myeloid Leukemia (CML) by Stepien, Anna, Martino, Alessandro, Canzian, Federico, Campa, Daniele, Stein, Angelika, Gora-Tybor, Joanna, Sacha, Tomasz, Link-Lenczowska, Dorota, Florek, Izabela, Prejzner, Witold, Specht-Szwoch, Zofia, Calbecka, Malgorzata, Rymko, Marcin, Dudzinski, Marek, Gaj, Pawel, Robak, Tadeusz, Warzocha, Krzysztof, Jamroziak, Krzysztof

“…Background: Inherited background in mechanisms regulating cellular uptake, elimination and metabolism of imatinib and other BCR-ABL tyrosine kinase inhibitors…”
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Cladribine in a weekly versus daily schedule for untreated active hairy cell leukemia: final report from the Polish Adult Leukemia Group (PALG) of a prospective, randomized, multicenter trial by Robak, Tadeusz, Jamroziak, Krzysztof, Gora-Tybor, Joanna, Blonski, Jerzy Z., Kasznicki, Marek, Dwilewicz-Trojaczek, Jadwiga, Wiater, Elzbieta, Zdunczyk, Andrzej, Dybowicz, Jacek, Dmoszynska, Anna, Wojtaszko, Maria, Zdziarska, Barbara, Calbecka, Malgorzata, Kostyra, Aleksandra, Hellmann, Andrzej, Lewandowski, Krzysztof, Stella-Holowiecka, Beata, Sulek, Kazimierz, Gawronski, Krzysztof, Skotnicki, Aleksander B., Nowak, Wieslaw, Zawilska, Krystyna, Molendowicz-Portala, Lucyna, Kloczko, Janusz, Sokolowski, Jarosław, Warzocha, Krzysztof, Seferyńska, Ilona, Ceglarek, Bernardeta, Konopka, Lech

“…Cladribine (2-chlorodeoxyadenosine, 2-CdA) treatment-associated infections may shorten potentially long-term survival in hairy cell leukemia (HCL). In search…”
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Treatment of elderly patients with acute myeloid leukemia adjusted for performance status and presence of comorbidities: a Polish Adult Leukemia Group study by Budziszewska, Bozena Katarzyna, Pluta, Agnieszka, Sulek, Kazimierz, Wierzbowska, Agnieszka, Robak, Tadeusz, Giebel, Sebastian, Holowiecka-Goral, Aleksandra, Sawicki, Waldemar, Ejduk, Anna, Patkowska, Elzbieta, Manko, Joanna, Gajkowska-Kulik, Justyna, Piszcz, Jaroslaw, Mordak-Domagala, Monika, Madry, Krzysztof, Holowiecki, Jerzy, Kyrcz-Krzemien, Slawomira, Nowakowska-Domagala, Maria, Dmoszynska, Anna, Calbecka, Malgorzata, Kloczko, Janusz, Wiktor Jędrzejczak, Wiesław, Lange, Andrzej, Razny, Malgorzata, Bilinski, Przemyslaw, Warzocha, Krzysztof, Lech-Maranda, Ewa

“…This prospective study estimated outcomes in 509 elderly patients with acute myeloid leukemia (AML) with different treatment approaches depending on Eastern…”
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Cereblon (CRBN) Gene Polymorphisms Predict Clinical Response and Progression-Free Survival in Multiple Myeloma Patients Treated with Lenalidomide: A Pharmacogenetic Study of Immense Consortium by Iskierka-Jazdzewska, Elzbieta, Stepien, Anna, Canzian, Federico, Martino, Alessandro, Campa, Daniele, Stein, Angelika, Krawczyk-Kulis, Malgorzata, Rybicka, Malwina, Kyrcz-Krzemien, Slawomira, Butrym, Aleksandra K., Mazur, Grzegorz, Jurczyszyn, Artur J., Zawirska, Daria, Grzasko, Norbert, Tomczak, Waldemar, Subocz, Edyta, Watek, Marzena, Pasiarski, Marcin, Rymko, Marcin, Calbecka, Malgorzata, Druzd-Sitek, Agnieszka, Walewski, Jan, Kruszewski, Marcin, Razny, Malgorzata, Zaucha, Jan M, Dudzinski, Marek, Gaj, Pawel, Warzocha, Krzysztof, Jamroziak, Krzysztof

“…Background: Cereblon (CRBN), a subunit of cullin 4-based E3 ubiquitine ligase complex, has been characterized as the main immunomodulatory drugs (IMiDs),…”
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Long-term results of the Polish Adult Leukemia Group PALG-CLL2 phase III randomized study comparing cladribine-based combinations in chronic lymphocytic leukemia by Robak, Tadeusz, Blonski, Jerzy Z., Gora-Tybor, Joanna, Calbecka, Malgorzata, Dwilewicz-Trojaczek, Jadwiga, Boguradzki, Piotr, Dmoszynska, Anna, Kowal, Malgorzata, Kloczko, Janusz, Piszcz, Jaroslaw, Stella-Holowiecka, Beata, Sulek, Kazimierz, Kuliczkowski, Kazimierz, Potoczek, Stanislaw, Warzocha, Krzysztof, Lech-Maranda, Ewa, Skotnicki, Aleksander B., Piotrowska, Magdalena, Moskwa, Andrzej, Zawilska, Krystyna, Jamroziak, Krzysztof

“…Abstract Long-term outcomes following newer therapies for chronic lymphocytic leukemia (CLL) have rarely been reported. This article presents the results of…”
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Imatinib at Weekly Dosage May Induce and Maintain Haematologic and Molecular Remission in Chronic Eosinophilic Leukemia Harbouring FIP1L1-PDGFRA Fusion Gene- An Extended Follow-up Study by Helbig, Grzegorz, Calbecka, Malgorzata, Gajkowska, Justyna, Moskwa, Andrzej, Urbanowicz, Alina, Swiderska, Alina, Najda, Jacek, Krzemien, Slawomira

“…Background. A small proportion of patients with hypereosinophilic syndrome (HES) demonstrate the presence of an interstitial deletion in chromosome 4 leading…”
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Immune thrombocytopenia in patients with chronic lymphocytic leukemia treated with cladribine-based regiments or chlorambucil - follow-up of PALG-CLL randomized trials by Blonski, Jerzy Z., Robak, Tadeusz, Chojnowski, Krzysztof, Gora-Tybor, Joanna, Warzocha, Krzysztof, Ceglarek, Bernadetta, Seferynska, Ilona, Calbecka, Malgorzata, Kostyra, Aleksandra, Stella-Holowiecka, Beata, Kloczko, Janusz, Dmoszynska, Anna, Kowal, Malgorzata, Lewandowski, Krzysztof, Dwilewicz-Trojaczek, Jadwiga, Wiater, Elzbieta, Kuliczkowski, Kazimierz, Potoczek, Stanislaw, Hellmann, Andrzej, Mital, Andrzej, Skotnicki, Aleksander, Nowak, Wieslaw, Sulek, Kazimierz, Zawilska, Krystyna, Trelinski, Jacek

“…Objectives The relationship between treatments of chronic lymphocytic leukemia (CLL) with cladribine (2‐CdA) or chlorambucil and immune thrombocytopenia (IT)…”
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