Search Results - "CALAZA, MANUEL"
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Assessment of global DNA methylation in peripheral blood cell subpopulations of early rheumatoid arthritis before and after methotrexate
Published in Arthritis research & therapy (29-08-2015)“…DNA methylation is an epigenetic mechanism regulating gene expression that has been insufficiently studied in the blood of rheumatoid arthritis (RA) patients,…”
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Novel Gene-Based Analysis of ASD GWAS: Insight Into the Biological Role of Associated Genes
Published in Frontiers in genetics (09-08-2019)“…Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by its significant social impact and high heritability. The latest meta-analysis…”
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LIPG endothelial lipase and breast cancer risk by subtypes
Published in Scientific reports (17-05-2021)“…Experimental data showed that endothelial lipase (LIPG) is a crucial player in breast cancer. However, very limited data exists on the role of LIPG on the risk…”
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Gene-based analysis of ADHD using PASCAL: a biological insight into the novel associated genes
Published in BMC medical genomics (24-10-2019)“…Attention-Deficit Hyperactivity Disorder (ADHD) is a complex neurodevelopmental disorder (NDD) which may significantly impact on the affected individual's…”
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Assessment of Osteoarthritis Candidate Genes in a Meta‐Analysis of Nine Genome‐Wide Association Studies
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-04-2014)“…Objective To assess candidate genes for association with osteoarthritis (OA) and identify promising genetic factors and, secondarily, to assess the candidate…”
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Increased expression of fatty-acid and calcium metabolism genes in failing human heart
Published in PloS one (06-06-2012)“…Heart failure (HF) involves alterations in metabolism, but little is known about cardiomyopathy-(CM)-specific or diabetes-independent alterations in gene…”
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Further evidence of subphenotype association with systemic lupus erythematosus susceptibility loci: a European cases only study
Published in PloS one (26-09-2012)“…Systemic Lupus Erythematosus (SLE) shows a spectrum of clinical manifestations that complicate its diagnosis, treatment and research. This variability is…”
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Reference genes for normalization of gene expression studies in human osteoarthritic articular cartilage
Published in BMC molecular biology (29-01-2008)“…Assessment of gene expression is an important component of osteoarthritis (OA) research, greatly improved by the development of quantitative real-time PCR…”
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Daniel 9.24-27: Poetry, “Elevated Prose,” or Something Else?
Published in The Bible translator (01-08-2024)“…Daniel 9.24-27 is addressed as a case study for testing a widely accepted list of formal criteria for diagnosing where a passage gravitates toward within the…”
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Association of systemic lupus erythematosus clinical features with European population genetic substructure
Published in PloS one (14-12-2011)“…Systemic Lupus Erythematosus (SLE) is an autoimmune disease with a very varied spectrum of clinical manifestations that could be partly determined by genetic…”
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Expressed sequence tags (ESTs) from immune tissues of turbot (Scophthalmus maximus) challenged with pathogens
Published in BMC veterinary research (25-09-2008)“…The turbot (Scophthalmus maximus; Scophthalmidae; Pleuronectiformes) is a flatfish species of great relevance for marine aquaculture in Europe. In contrast to…”
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Lack of Association with Rheumatoid Arthritis of Selected Polymorphisms in 4 Candidate Genes: CFH, CD209, Eotaxin-3, and MHC2TA
Published in Journal of rheumatology (01-08-2009)“…Objective. To investigate associations with rheumatoid arthritis (RA) of single-nucleotide polymorphisms (SNP) in 4 candidate genes, complement factor H (CFH),…”
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Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen
Published in Nature communications (17-06-2019)“…The effectiveness of most cancer targeted therapies is short-lived. Tumors often develop resistance that might be overcome with drug combinations. However, the…”
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Genetic distance as an alternative to physical distance for definition of gene units in association studies
Published in BMC genomics (28-05-2014)“…Some association studies, as the implemented in VEGAS, ALIGATOR, i-GSEA4GWAS, GSA-SNP and other software tools, use genes as the unit of analysis. These genes…”
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Abstract 2269: Circulating lipids and breast cancer subtypes in a Spanish population
Published in Cancer research (Chicago, Ill.) (01-07-2017)“…Background. Although several studies have looked at the circulating lipids-overall breast cancer relationship, no prior investigation has examined this…”
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Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis
Published in Nature communications (23-08-2016)“…Rheumatoid arthritis (RA) affects millions world-wide. While anti-TNF treatment is widely used to reduce disease progression, treatment fails in ∼one-third of…”
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Nesfatin-1 in Human and Murine Cardiomyocytes: Synthesis, Secretion, and Mobilization of GLUT-4
Published in Endocrinology (Philadelphia) (01-12-2013)“…Nesfatin-1, a satiety-inducing peptide identified in hypothalamic regions that regulate energy balance, is an integral regulator of energy homeostasis and a…”
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Lack of interaction between systemic lupus erythematosus-associated polymorphisms in TYK2 and IRF5
Published in Journal of rheumatology (01-03-2010)Get full text
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Brief Report: Lack of Replication of an Association Between Anti–Citrullinated Fibrinogen and Subclinical Atherosclerosis in Patients With Rheumatoid Arthritis
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-11-2015)“…Objective Results of a recent study suggested that the excess cardiovascular (CV) risk observed in patients with rheumatoid arthritis (RA) could be partially…”
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Identification of a novel susceptibility locus at 13q34 and refinement of the 20p12.2 region as a multi-signal locus associated with bladder cancer risk in individuals of European ancestry
Published in Human molecular genetics (15-03-2016)“…Candidate gene and genome-wide association studies (GWAS) have identified 15 independent genomic regions associated with bladder cancer risk. In search for…”
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