Search Results - "CALANDRA, RICARDO S."
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1
Cyclooxygenase and prostaglandins in somatic cell populations of the testis
Published in Reproduction (Cambridge, England) (01-04-2015)“…Prostaglandins (PGs) are synthesized through the action of the rate-limiting enzyme cyclooxygenase (COX) and further specific enzymes. The development of…”
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2
Hormonal Regulation of Follicle-Stimulating Hormone Glycosylation in Males
Published in Frontiers in endocrinology (Lausanne) (2019)“…The Follicle-Stimulating Hormone plays an important role in the regulation of gametogenesis. It is synthesized and secreted as a family of glycoforms with…”
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3
Number, distribution pattern, and identification of macrophages in the testes of infertile men
Published in Fertility and sterility (01-08-2002)“…To investigate the number, location, and secretory products of macrophages in human testes showing normal and abnormal spermatogenesis. Evaluation of…”
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4
A Prostaglandin D2 system in the human testis
Published in Fertility and sterility (01-07-2007)“…As shown recently, cyclooxygenase 2 (COX2), the inducible key enzyme for the prostaglandin (PG) biosynthetic pathway, is abundantly present in interstitial…”
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5
Expression of the TGF-beta1 system in human testicular pathologies
Published in Reproductive biology and endocrinology (02-12-2010)“…In non-obstructive azoospermia, histological patterns of Sertoli cell-only Syndrome (SCO) and hypospermatogenesis (H) are commonly found. In these pathologies,…”
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6
Elevated chorionic gonadotropic hormone in transgenic mice induces parthenogenetic activation and ovarian teratomas
Published in Molecular and cellular endocrinology (01-06-2024)“…Both male and female reproductive functions are impacted by altered gonadotrophin secretion and action, which may also influence the development of endocrine…”
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7
Male and female gonadal ageing: its impact on health span and life span
Published in Mechanisms of ageing and development (01-07-2021)“…•Gonadal ageing involves local inflammatory, oxidative and apoptotic events.•Vertebrate animal models are commonly used to investigate gonadal ageing.•Gonadal…”
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8
Testosterone induction of prostaglandin-endoperoxide synthase 2 expression and prostaglandin F2α production in hamster Leydig cells
Published in Reproduction (Cambridge, England) (01-07-2009)“…We have previously observed expression of prostaglandin-endoperoxide synthase 2 (PTGS2), the key enzyme in the biosynthesis of prostaglandins (PGs), in…”
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9
Melatonin improves oxidative state and lactate metabolism in rodent Sertoli cells
Published in Molecular and cellular endocrinology (01-10-2023)“…Antioxidant actions of melatonin and its impact on testicular function and fertility have already been described. Considering that Sertoli cells contribute to…”
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10
Melatonin daily oral supplementation attenuates inflammation and oxidative stress in testes of men with altered spermatogenesis of unknown aetiology
Published in Molecular and cellular endocrinology (15-09-2020)“…We have previously shown an inverse correlation between testicular melatonin concentration and inflammation/oxidative stress-related markers levels in…”
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11
Pleiotropic actions of melatonin in testicular peritubular myoid cells of immature Syrian hamsters
Published in Biochimica et biophysica acta. General subjects (01-10-2022)“…Peritubular myoid cells are emerging as key regulators of testicular function in adulthood. However, little is known about the role of testicular peritubular…”
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12
Evidence for a GABAergic system in rodent and human testis: local GABA production and GABA receptors
Published in Neuroendocrinology (01-05-2003)“…The major neurotransmitter of the central nervous system, gamma-aminobutyric acid (GABA), exerts its actions through GABA(A), GABA(B) and GABA(C) receptors…”
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13
Reactive oxygen species (ROS) production triggered by prostaglandin D2 (PGD2) regulates lactate dehydrogenase (LDH) expression/activity in TM4 Sertoli cells
Published in Molecular and cellular endocrinology (15-10-2016)“…Reactive oxygen species (ROS) regulate testicular function in health and disease. We previously described a prostaglandin D2 (PGD2) system in Sertoli cells…”
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14
New insights into melatonin/CRH signaling in hamster Leydig cells
Published in General and comparative endocrinology (01-08-2012)“…Graphical abstract Highlights ► Melatonin/CRH as stimulatory factors of tyrosine phosphatases. ► Melatonin/CRH as inhibitory factors of erk and jnk…”
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15
Hyperprolactinemia induced by hCG leads to metabolic disturbances in female mice
Published in Journal of endocrinology (01-07-2016)“…The metabolic syndrome is a growing epidemic; it increases the risk for diabetes, cardiovascular disease, fatty liver, and several cancers. Several reports…”
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16
Short-Term Pharmacological Suppression of the Hyperprolactinemia of Infertile hCG-Overproducing Female Mice Persistently Restores Their Fertility
Published in Endocrinology (Philadelphia) (01-12-2012)“…Female infertility is often associated with deregulation of hormonal networks, and hyperprolactinemia is one of the most common endocrine disorders of the…”
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17
Direct Effect of Melatonin on Syrian Hamster Testes: Melatonin Subtype 1a Receptors, Inhibition of Androgen Production, and Interaction with the Local Corticotropin-Releasing Hormone System
Published in Endocrinology (Philadelphia) (01-03-2005)“…Besides the hypothalamus and pituitary, melatonin action at the testicular level has been recently suggested. Therefore, we investigated in the Syrian hamster,…”
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18
Cyclooxygenase-2 and Prostaglandin F2α in Syrian Hamster Leydig Cells: Inhibitory Role on Luteinizing Hormone/Human Chorionic Gonadotropin-Stimulated Testosterone Production
Published in Endocrinology (Philadelphia) (01-09-2006)“…We have previously found that cyclooxygenase-2 (COX-2), a key enzyme in the biosynthesis of prostaglandins (PGs), is present in the testicular interstitial…”
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19
Elevated hypothalamic aromatization at the onset of precocious puberty in transgenic female mice hypersecreting human chorionic gonadotropin: Effect of androgens
Published in Molecular and cellular endocrinology (05-06-2014)“…•Transgenic female mice for hCG exhibit elevated androgens and precocious puberty.•Aromatase levels are increased at the hypothalamic preoptic area of…”
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20
Direct Effect of Ghrelin on Leptin Production by Cultured Rat White Adipocytes
Published in Obesity (Silver Spring, Md.) (01-01-2006)“…Objective: Because ghrelin is known to stimulate adipogenesis, we tested whether ghrelin could contribute to the maintenance of homeostasis, directly affecting…”
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