Search Results - "CALAME, K"

Plasma cells: finding new light at the end of B cell development by Calame, Kathryn L

“…Plasma cells are cellular factories devoted entirely to the manufacture and export of a single product: soluble immunoglobulin (Ig). As the final mediators of…”
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Commitment of B Lymphocytes to a Plasma Cell Fate Is Associated with Blimp-1 Expression In Vivo by Angelin-Duclos, Cristina, Cattoretti, Giorgio, Lin, Kuo-I, Calame, Kathryn

“…B lymphocyte-induced maturation protein-1 (Blimp-1) is a transcriptional repressor that is sufficient to trigger terminal differentiation in the B cell…”
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REGULATORY MECHANISMS THAT DETERMINE THE DEVELOPMENT AND FUNCTION OF PLASMA CELLS by Calame, Kathryn L, Lin, Kuo-I, Tunyaplin, Chainarong

“…Plasma cells are terminally differentiated final effectors of the humoral immune response. Plasma cells that result from antigen activation of B-1 and marginal…”
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CCAAT/Enhancer Binding Protein (C/EBP) Sites are Required for HIV-1 Replication in Primary Macrophages but not CD4+T Cells by Henderson, A. J., Calame, K. L.

“…The importance of CCAAT/enhancer binding proteins (C/EBPs) and binding sites for HIV-1 replication in primary macrophages, T cell lines and primary CD4+T cells…”
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C/EBP proteins activate transcription from the human immunodeficiency virus type 1 long terminal repeat in macrophages/monocytes by Henderson, A J, Zou, X, Calame, K L

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Repression of c-myc Is Necessary but Not Sufficient for Terminal Differentiation of B Lymphocytes In Vitro by Lin, Kuo-I, Lin, Yi, Calame, Kathryn

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Inhibition of Transcriptional Regulator Yin-Yang-1 by Association with c-Myc by Shrivastava, A., Saleque, S., Kalpana, G. V., Artandi, S., Goff, S. P., Calame, K.

“…Yin-Yang-1 (YY1) regulates the transcription of many genes, including the oncogenes c-fos and c-myc. Depending on the context, YY1 acts as a transcriptional…”
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An immunoglobulin heavy chain variable region gene is generated from three segments of DNA: VH, D and JH. 1980 by Early, P, Huang, H, Davis, M, Calame, K, Hood, L

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Polyamines alter sequence-specific DNA-protein interactions by Panagiotidis, Christos A., Artandi, Steven, Calame, Kathryn, Silverstein, Saul J.

“…The polyamines are abundant blogenlc cations implicated in many biological processes. Despite a plethora of evidence on polyamine-induced DNA conforma-tional…”
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YY1 and c-Myc Associate in vivo in a Manner that Depends on c-Myc Levels by Shrivastava, Ajay, Yu, Jin, Artandi, Steven, Calame, Kathryn

“…The c-Myc oncoprotein has previously been shown to associate with transcription regulator YY1 and to inhibit its activity. We show herein that endogenous c-Myc…”
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Regulation of plasma-cell development by Calame, Kathryn, Shapiro-Shelef, Miriam

“…Plasma cells are the terminally differentiated, non-dividing effector cells of the B-cell lineage. They are cellular factories devoted to the task of…”
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Yin-yang 1 activates the c-myc promoter by RIGGS, K. J, SALEQUE, S, KWOK-KIN WONG, MERRELL, K. T, JENG-SHIN LEE, YANG SHI, CALAME, K

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Multiple DNA Sequence Elements are Necessary for the Function of an Immunoglobulin Heavy Chain Promoter by Eaton, Suzanne, Calame, Kathryn

“…Sequences required for the function of the mouse V1 immunoglobulin heavy chain variable-region (VH) promoter were identified by transient transfection of the…”
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The C/EBP family of proteins distorts DNA upon binding but does not introduce a large directed bend by Avitahl, N, Calame, K

“…The DNA-bending properties of several C/EBP family proteins, bound to two different sites, have been determined using circular permutation and phasing…”
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GATA elements are necessary for the activity and tissue specificity of the T-cell receptor beta-chain transcriptional enhancer by HENDERSON, A. J, MCDOUGALL, S, LEIDEN, J, CALAME, K. L

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Monoclonal IgM Rheumatoid Factors Bind IgG at a Discontinuous Epitope Comprised of Amino Acid Loops from Heavy-Chain Constant-Region Domains 2 and 3 by Artandi, S. E., Calame, K. L., Morrison, S. L., Bonagura, V. R.

“…A combination of site-directed mutagenesis and exon exchange has been used to further define the structure on IgG recognized by monoclonal IgM rheumatoid…”
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TIF1β functions as a coactivator for C/EBPβ and is required for induced differentiation in the myelomonocytic cell line U937 by Rooney, John W., Calame, Kathryn L.

“…Representational difference analysis (RDA) cloning has identified transcriptional intermediary factor 1 beta ( TIF1β ) as a gene inducibly expressed early…”
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Differential stability of c-myc mRNAS in a cell-free system by RUI PEI, CALAME, K

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Transcriptional repressor Blimp-1 regulates T cell homeostasis and function by Calame, Kathryn, Martins, Gislâine A, Cimmino, Luisa, Shapiro-Shelef, Miriam, Szabolcs, Matthias, Herron, Alan, Magnusdottir, Erna

“…The B lymphocyte-induced maturation protein 1 (Blimp-1) transcriptional repressor is required for terminal differentiation of B lymphocytes. Here we document a…”
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v-Abl activates c-myc transcription through the E2F site by Wong, Kwok-Kin, Zou, Xiaoming, Merrell, Kevin T., Patel, Amanda J., Marcu, Kenneth B., Chellappan, Srikumar, Calame, Kathryn

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