Search Results - "CADEIRAS, Martin"
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Personalized survival predictions via Trees of Predictors: An application to cardiac transplantation
Published in PloS one (28-03-2018)“…Risk prediction is crucial in many areas of medical practice, such as cardiac transplantation, but existing clinical risk-scoring methods have suboptimal…”
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Dietary Management of Heart Failure: DASH Diet and Precision Nutrition Perspectives
Published in Nutrients (10-12-2021)“…Heart failure (HF) is a major health care burden increasing in prevalence over time. Effective, evidence-based interventions for HF prevention and management…”
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An integrated molecular diagnostic report for heart transplant biopsies using an ensemble of diagnostic algorithms
Published in The Journal of heart and lung transplantation (01-06-2019)“…We previously reported a microarray-based diagnostic system for heart transplant endomyocardial biopsies (EMBs), using either 3-archetype (3AA) or 4-archetype…”
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Understanding the correlation between DSA, complement activation and antibody mediated rejection in heart transplant recipients
Published in Transplantation (01-10-2018)“…BACKGROUNDDonor specific HLA antibodies (DSA) are associated with increased rates of rejection and of graft failure in cardiac transplantation. The goal of…”
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Adaptive Content Tuning of Social Network Digital Health Interventions Using Control Systems Engineering for Precision Public Health: Cluster Randomized Controlled Trial
Published in Journal of medical Internet research (31-05-2023)“…Social media has emerged as an effective tool to mitigate preventable and costly health issues with social network interventions (SNIs), but a precision public…”
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Protein kinetic signatures of the remodeling heart following isoproterenol stimulation
Published in The Journal of clinical investigation (01-04-2014)“…Protein temporal dynamics play a critical role in time-dimensional pathophysiological processes, including the gradual cardiac remodeling that occurs in…”
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Association between preoperative peripheral blood mononuclear cell gene expression profiles, early postoperative organ function recovery potential and long-term survival in advanced heart failure patients undergoing mechanical circulatory support
Published in PloS one (13-12-2017)“…Multiorgan dysfunction syndrome contributes to adverse outcomes in advanced heart failure (AdHF) patients after mechanical circulatory support (MCS)…”
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Comparison of whole blood and peripheral blood mononuclear cell gene expression for evaluation of the perioperative inflammatory response in patients with advanced heart failure
Published in PloS one (17-12-2014)“…Heart failure (HF) prevalence is increasing in the United States. Mechanical Circulatory Support (MCS) therapy is an option for Advanced HF (AdHF) patients…”
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Regulation of Acetylation Restores Proteolytic Function of Diseased Myocardium in Mouse and Human
Published in Molecular & cellular proteomics (01-12-2013)“…Proteasome complexes play essential roles in maintaining cellular protein homeostasis and serve fundamental roles in cardiac function under normal and…”
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Reduced HLA Class II antibody response to proteasome inhibition in heart transplantation
Published in The Journal of heart and lung transplantation (01-06-2015)Get full text
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Characterization of ventricular assist device–mediated sensitization in the bridge-to-heart-transplantation patient
Published in The Journal of thoracic and cardiovascular surgery (01-04-2015)“…Objective Ventricular assist devices (VADs) are associated with increased anti–human leukocyte antigen antibody production. The purpose of this study is to…”
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Remote monitoring titration clinic to implement guideline-directed therapy for heart failure patients with reduced ejection fraction: a pilot quality-improvement intervention
Published in Frontiers in cardiovascular medicine (19-06-2023)“…Guideline-directed medical therapy (GDMT) is the recommended treatment for heart failure with reduced ejection fraction (HFrEF). However, the implementation…”
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Exploring the cardiac response to injury in heart transplant biopsies
Published in JCI insight (18-10-2018)“…Because injury is universal in organ transplantation, heart transplant endomyocardial biopsies present an opportunity to explore response to injury in heart…”
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Anthracycline induced cardiotoxicity: biomarkers and “Omics” technology in the era of patient specific care
Published in Clinical and translational medicine (10-05-2017)“…Anthracyclines are highly effective against a variety of malignancies. However, their dose-dependent cardiotoxic effects can potentially limit their use. In…”
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Integrative model of leukocyte genomics and organ dysfunction in heart failure patients requiring mechanical circulatory support: a prospective observational study
Published in BMC medical genomics (29-08-2017)“…The implantation of mechanical circulatory support devices in heart failure patients is associated with a systemic inflammatory response, potentially leading…”
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92438 Symptom Dynamics and Biomarkers of Disease Progression in Older Adult Patient-Caregiver Dyads During Care Transitions after Heart Failure Hospitalization: Study Design and Anticipated Results
Published in Journal of clinical and translational science (01-03-2021)“…ABSTRACT IMPACT: This study is designed to address a critical gap in our understanding of how aging patients and caregivers recognize and respond to clinically…”
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The Association of Shared Care Networks With 30-Day Heart Failure Excessive Hospital Readmissions: Longitudinal Observational Study
Published in JMIRx med (06-04-2022)“…BACKGROUNDHigher-than-expected heart failure (HF) readmissions affect half of US hospitals every year. The Hospital Reduction Readmission Program has reduced…”
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Upstream stimulatory factor-2 mediates quercetin-induced suppression of PAI-1 gene expression in human endothelial cells
Published in Journal of cellular biochemistry (15-10-2010)“…The polyphenol quercetin (Quer) represses expression of the cardiovascular disease risk factor plasminogen activator inhibitor‐1 (PAI‐1) in cultured…”
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Improvement in 2-year survival for ventricular assist device patients after implementation of an intensive surveillance protocol
Published in The Journal of heart and lung transplantation (01-08-2011)“…Background This study was conducted to determine the effect of a disease-management model termed an “intensive surveillance protocol” (ISP) on survival in…”
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