Search Results - "CACCIOPPOLI, CRISTINA"

Adipose Tissue Dysfunction and Obesity-Related Male Hypogonadism by Genchi, Valentina Annamaria, Rossi, Erica, Lauriola, Celeste, D’Oria, Rossella, Palma, Giuseppe, Borrelli, Anna, Caccioppoli, Cristina, Giorgino, Francesco, Cignarelli, Angelo

“…Obesity is a chronic illness associated with several metabolic derangements and comorbidities (i.e., insulin resistance, leptin resistance, diabetes, etc.) and…”
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Adipose Tissue Inflammation and Pulmonary Dysfunction in Obesity by Palma, Giuseppe, Sorice, Gian Pio, Genchi, Valentina Annamaria, Giordano, Fiorella, Caccioppoli, Cristina, D’Oria, Rossella, Marrano, Nicola, Biondi, Giuseppina, Giorgino, Francesco, Perrini, Sebastio

“…Obesity is a chronic disease caused by an excess of adipose tissue that may impair health by altering the functionality of various organs, including the lungs…”
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Reduced SIRT1 and SIRT2 expression promotes adipogenesis of human visceral adipose stem cells and associates with accumulation of visceral fat in human obesity by Perrini, Sebastio, Porro, Stefania, Nigro, Pasquale, Cignarelli, Angelo, Caccioppoli, Cristina, Genchi, Valentina Annamaria, Martines, Gennaro, De Fazio, Michele, Capuano, Palma, Natalicchio, Annalisa, Laviola, Luigi, Giorgino, Francesco

“…Background/Objectives The histone deacetylases SIRT1 and SIRT2 have been shown to be involved in the differentiation of rodent adipocyte precursors. In light…”
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Impaired Leptin Signalling in Obesity: Is Leptin a New Thermolipokine? by Genchi, Valentina Annamaria, D’Oria, Rossella, Palma, Giuseppe, Caccioppoli, Cristina, Cignarelli, Angelo, Natalicchio, Annalisa, Laviola, Luigi, Giorgino, Francesco, Perrini, Sebastio

“…Leptin is a principal adipose-derived hormone mostly implicated in the regulation of energy balance through the activation of anorexigenic neuronal pathways…”
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The p66Shc Redox Protein and the Emerging Complications of Diabetes by Biondi, Giuseppina, Marrano, Nicola, Borrelli, Anna, Rella, Martina, D’Oria, Rossella, Genchi, Valentina Annamaria, Caccioppoli, Cristina, Cignarelli, Angelo, Perrini, Sebastio, Laviola, Luigi, Giorgino, Francesco, Natalicchio, Annalisa

“…Diabetes mellitus is a chronic metabolic disease, the prevalence of which is constantly increasing worldwide. It is often burdened by disabling comorbidities…”
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Impact of Dysfunctional Adipose Tissue Depots on the Cardiovascular System by D'Oria, Rossella, Genchi, Valentina Annamaria, Caccioppoli, Cristina, Calderoni, Isabella, Marrano, Nicola, Biondi, Giuseppina, Borrelli, Anna, Di Gioia, Ludovico, Giorgino, Francesco, Laviola, Luigi

“…Obesity with its associated complications represents a social, economic and health problem of utmost importance worldwide. Specifically, obese patients carry a…”
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TNFα signals via p66(Shc) to induce E-Selectin, promote leukocyte transmigration and enhance permeability in human endothelial cells by Laviola, Luigi, Orlando, Maura Roberta, Incalza, Maria Angela, Caccioppoli, Cristina, Melchiorre, Mariangela, Leonardini, Anna, Cignarelli, Angelo, Tortosa, Federica, Labarbuta, Rossella, Martemucci, Sabina, Pacelli, Consiglia, Cocco, Tiziana, Perrini, Sebastio, Natalicchio, Annalisa, Giorgino, Francesco

“…Endothelial cells participate in inflammatory events leading to atherogenesis by regulating endothelial cell permeability via the expression of VE-Cadherin and…”
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Human chromosome 21 gene expression atlas in the mouse by Antonarakis, Stylianos E, Ballabio, Andrea, Reymond, Alexandre, Marigo, Valeria, Yaylaoglu, Murat B, Leoni, Antonio, Ucla, Catherine, Scamuffa, Nathalie, Caccioppoli, Cristina, Dermitzakis, Emmanouil T, Lyle, Robert, Banfi, Sandro, Eichele, Gregor

“…Genome-wide expression analyses have a crucial role in functional genomics. High resolution methods, such as RNA in situ hybridization provide an accurate…”
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1230-P: Isolation of Functional Endothelial Progenitor Cells from Human Adipose Tissue by CACCIOPPOLI, CRISTINA, PERRINI, SEBASTIO, GENCHI, VALENTINA ANNAMARIA, DORIA, ROSSELLA, PALMA, GIUSEPPE, CIGNARELLI, ANGELO, NATALICCHIO, ANNALISA, LAVIOLA, LUIGI, GIORGINO, FRANCESCO

“…Endothelial progenitor cells (EPCs) are key for angiogenic responses in multiple tissues and mediate a coordinate augmentation of the capillary network as…”
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438-P: Glucose-Dependent Insulinotropic Polypeptide Prevents Palmitate-Induced Apoptosis, but Not Autophagy and Stress Kinase Activation in Human Cardiac Progenitor Cells by Calderoni, Isabella, Doria, Rossella, Caccioppoli, Cristina, Colabufo, Carmela, Genchi, Valentina Annamaria, Palma, Giuseppe, Santarpino, Giuseppe, Milano, Aldo D, Bottio, Tomaso, Leonardini, Anna, Natalicchio, Annalisa, Perrini, Sebastio, Cignarelli, Angelo, Giorgino, Francesco, Laviola, Luigi

“…Introduction & Objective: The gut incretin hormone glucose-dependent insulinotropic polypeptide (GIP) plays key roles in metabolic regulation. Evidence…”
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307-OR: Defective G-CSF in the Secretome of Epicardial Adipose Cells Favors Apoptosis and Cellular Stress of Cardiac Progenitor Cells in Human Obesity by Palma, Giuseppe, Caccioppoli, Cristina, Doria, Rossella, Genchi, Valentina Annamaria, Calderoni, Isabella, Bottio, Tomaso, Santarpino, Giuseppe, Cignarelli, Angelo, Natalicchio, Annalisa, Laviola, Luigi, Pezzolla, Angela, Valverde, Angela M, Milano, Aldo D, Giorgino, Francesco, Perrini, Sebastio

“…Introduction and Objective: Granulocyte colony-stimulating factor (G-CSF) was reported to induce myocardial regeneration by promoting mobilization of bone…”
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1414-P: Dapagliflozin Protects Human Cardiac Progenitor Cells from Deleterious Effects of the Secretome from Visceral Adipose Cells of Obese Subjects by PALMA, GIUSEPPE, CACCIOPPOLI, CRISTINA, DORIA, ROSSELLA, GENCHI, VALENTINA ANNAMARIA, SANTARPINO, GIUSEPPE, CIGNARELLI, ANGELO, NATALICCHIO, ANNALISA, LAVIOLA, LUIGI, PEZZOLLA, ANGELA, GIORGINO, FRANCESCO, PERRINI, SEBASTIO

“…Dysfunction of visceral and epicardial adipose tissue may alter heart performance and promote adverse cardiovascular outcomes in obesity and diabetes. We…”
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441-P: Oleate Prevents Palmitate-Induced Abnormalities in Insulin Signaling in Human Cardiac Progenitor Cells by Inhibiting p38 MAPK and c-Jun Phosphorylation by DORIA, ROSSELLA, CALDERONI, ISABELLA, CACCIOPPOLI, CRISTINA, GENCHI, VALENTINA ANNAMARIA, SANTARPINO, GIUSEPPE, LEONARDINI, ANNA, NATALICCHIO, ANNALISA, PERRINI, SEBASTIO, CIGNARELLI, ANGELO, GIORGINO, FRANCESCO, LAVIOLA, LUIGI

“…Elevated saturated fatty acid deposition in the heart results in insulin resistance, stress kinase activation, and increased cardiovascular risk in humans. The…”
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The p66[sup.Shc] Redox Protein and the Emerging Complications of Diabetes by Biondi, Giuseppina, Marrano, Nicola, Borrelli, Anna, Rella, Ma, D’Oria, Rossella, Genchi, Valentina Annamaria, Caccioppoli, Cristina, Cignarelli, Angelo, Perrini, Sebastio, Laviola, Luigi, Giorgino, Francesco, Natalicchio, Annalisa

“…Diabetes mellitus is a chronic metabolic disease, the prevalence of which is constantly increasing worldwide. It is often burdened by disabling comorbidities…”
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246-OR: Dapagliflozin Counteracts the Proapoptotic Effects of the Secretome of Visceral Adipose Cells from Obese Subjects in Human Cardiac Progenitor Cells via the SGLT2 Cotransporter by PALMA, GIUSEPPE, CACCIOPPOLI, CRISTINA, DORIA, ROSSELLA, ANNAMARIA GENCHI, VALENTINA, CALDERONI, ISABELLA, BRAUN, ANTONIO, SANTARPINO, GIUSEPPE, MILANO, ALDO D., CIGNARELLI, ANGELO, NATALICCHIO, ANNALISA, LAVIOLA, LUIGI, PEZZOLLA, ANGELA, GIORGINO, FRANCESCO, PERRINI, SEBASTIO

“…Dapagliflozin (DAPA), an SGLT2 inhibitor, has been shown to counteract heart failure outcomes in subjects with obesity and diabetes. We investigated the…”
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38-OR: Insulin Prevents Palmitate-Induced Stress Kinase Activation, Autophagy, and Apoptosis in Human Cardiac Progenitor Cells by CALDERONI, ISABELLA, DORIA, ROSSELLA, CACCIOPPOLI, CRISTINA, ANNAMARIA GENCHI, VALENTINA, PALMA, GIUSEPPE, SANTARPINO, GIUSEPPE, MILANO, ALDO D., LEONARDINI, ANNA, NATALICCHIO, ANNALISA, PERRINI, SEBASTIO, CIGNARELLI, ANGELO, GIORGINO, FRANCESCO, LAVIOLA, LUIGI

“…Abnormal accumulation of saturated fatty acids in the heart results in insulin resistance, stress kinase activation, and increased cardiovascular risk in…”
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410-P: Effects of Palmitate and Oleate on Apoptosis, Autophagy, Stress, Kinase Phosphorylation, and Enzymes of Fatty Acid Oxidation in Human Cardiac Progenitor Cells from Control and Diabetic Subjects by LAVIOLA, LUIGI, SCHIPANI, ROSSELLA, DORIA, ROSSELLA, CACCIOPPOLI, CRISTINA, LEONARDINI, ANNA, NATALICCHIO, ANNALISA, PERRINI, SEBASTIO, CIGNARELLI, ANGELO, GIORGINO, FRANCESCO

“…Elevated circulating levels of palmitate are associated with high cardiovascular risk in diabetes. In contrast, oleate prevents palmitate-induced cytotoxic…”
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374-P: Oleate Prevents Palmitate-Induced Abnormalities in Insulin Signaling in Human Cardiac Progenitor Cells by DORIA, ROSSELLA, CACCIOPPOLI, CRISTINA, SCHIPANI, ROSSELLA, GENCHI, VALENTINA ANNAMARIA, LEONARDINI, ANNA, NATALICCHIO, ANNALISA, PERRINI, SEBASTIO, CIGNARELLI, ANGELO, LAVIOLA, LUIGI, GIORGINO, FRANCESCO

“…Myocardial ectopic lipid deposition has been associated with insulin resistance and cardiovascular risk. Palmitate, one of the most abundant saturated fatty…”
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The p66Shc Protein Mediates Insulin Resistance and Secretory Dysfunction in Pancreatic Beta-Cells Under Lipotoxic Conditions by Biondi, Giuseppina, Marrano, Nicola, Dipaola, Lucia, Borrelli, Anna, Rella, Martina, D'Oria, Rossella, Genchi, Valentina A, Caccioppoli, Cristina, Porreca, Immacolata, Cignarelli, Angelo, Perrini, Sebastio, Marchetti, Piero, Vincenti, Leonardo, Laviola, Luigi, Giorgino, Francesco, Natalicchio, Annalisa

“…We evaluated the role of the p66Shc redox adaptor protein in pancreatic beta-cell insulin resistance that develops under lipotoxic conditions and with excess…”
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1762-P: Insulin Receptor Isoforms in Human Adipose Tissue and Adipose Stem Cells by GENCHI, VALENTINA ANNAMARIA, CIGNARELLI, ANGELO, PERRINI, SEBASTIO, PORRO, STEFANIA, CACCIOPPOLI, CRISTINA, NATALICCHIO, ANNALISA, LAVIOLA, LUIGI, GIORGINO, FRANCESCO

“…Insulin regulates the development and metabolism of adipose tissue (AT) by activating its tyrosine kinase receptor in this tissue. The insulin receptor (IR)…”
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