Search Results - "CABRAL, LUCIO M."
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The xylooligosaccharide addition and sodium reduction in requeijão cremoso processed cheese
Published in Food research international (01-05-2018)“…The addition of xylooligosaccharide (XOS), sodium reduction and flavor enhancers (arginine and yeast extract) on the manufacture of requeijão cremoso processed…”
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2
Probing insulin bioactivity in oral nanoparticles produced by ultrasonication-assisted emulsification/internal gelation
Published in International journal of nanomedicine (18-09-2015)“…Alginate-dextran sulfate-based particles obtained by emulsification/internal gelation technology can be considered suitable carriers for oral insulin delivery…”
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3
Synthesis and mechanistic evaluation of novel N’-benzylidene-carbohydrazide-1H-pyrazolo[3,4-b]pyridine derivatives as non-anionic antiplatelet agents
Published in European journal of medicinal chemistry (28-07-2017)“…Cardiovascular diseases (CVDs) account for over 17 million deaths globally each year, with atherosclerosis as the underlying cause of most CVDs. Herein we…”
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4
Molecular Modeling Studies of the Structural, Electronic, and UV Absorption Properties of Benzophenone Derivatives
Published in The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory (15-11-2012)“…Benzophenone derivatives (BZP), an important class of organic UV filters, are widely used in sunscreen products due to their ability to absorb in the UVA and…”
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5
Sodium montmorillonite/amine-containing drugs complexes: new insights on intercalated drugs arrangement into layered carrier material
Published in PloS one (24-03-2015)“…Layered drug delivery carriers are current targets of nanotechnology studies since they are able to accommodate pharmacologically active substances and are…”
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6
In vitro physiological and antibacterial characterization of ZnO nanoparticle composites in simulated porcine gastric and enteric fluids
Published in BMC veterinary research (17-06-2017)“…Diarrhea in piglets is one of the main causes of animal death after weaning; zinc oxide (ZnO) has been used in high doses for the control of this sickness. The…”
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7
Suspected adverse drug reactions reported for Brazilian children: cross-sectional study
Published in Jornal de pediatria (01-11-2019)“…To assess spontaneous reports of suspected adverse drug reactions in children aged 0–12 years from the Brazilian Health Regulatory Agency between 2008 and…”
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8
Identification, characterization and in silico ADMET prediction of Roflumilast degradation products
Published in Journal of pharmaceutical and biomedical analysis (10-05-2017)“…•Roflumilast produces eleven degradation products in alkaline/ acidic hydrolysis, photolysis and oxidative stress conditions.•Roflumilast tablets produce two…”
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9
Titanium dioxide-montmorillonite nanocomposite as photoprotective agent against ultraviolet B radiation-induced mutagenesis in Saccharomyces cerevisiae: a potential candidate for safer sunscreens
Published in Journal of pharmaceutical sciences (01-08-2014)“…Photoprotective potential and biological consequences (mutagenic potential) of octyl-dimethyl-PABA (ODP), titanium dioxide (TiO2 ), and montmorillonite (MMT)…”
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10
Synthesis and Evaluation of Antiproliferative Activity, Topoisomerase IIα Inhibition, DNA Binding and Non-Clinical Toxicity of New Acridine–Thiosemicarbazone Derivatives
Published in Pharmaceuticals (Basel, Switzerland) (01-09-2022)“…In this study, we report the synthesis of twenty new acridine–thiosemicarbazone derivatives and their antiproliferative activities. Mechanisms of action such…”
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11
Efavirenz dissolution enhancement III: Colloid milling, pharmacokinetics and electronic tongue evaluation
Published in European journal of pharmaceutical sciences (01-03-2017)“…Efavirenz (EFV), a non-nucleoside reverse transcriptase inhibitor (NNRTI), is part of first-line therapy for the treatment of human immunodeficiency virus type…”
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12
Characterization and effect of nanocomplexed fluoride solutions on the inhibition of enamel demineralization created by a multispecies cariogenic biofilm model
Published in Clinical oral investigations (01-11-2020)“…Objectives The aim of this study was to assess the in vitro caries preventive effect of nanocomplexed solutions of hydroxypropyl-β-cyclodextrin and…”
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13
Toxicological assessment of SGLT2 inhibitors metabolites using in silico approach
Published in Anais da Academia Brasileira de Ciências (01-01-2022)“…Abstract Sodium-glucose cotransporter 2 inhibitors (SGLT2i) are the latest class of drugs approved to treat type 2 DM (T2DM). Although adverse effects are…”
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14
Development of a validation protocol method for nucleic acid testing to detect human immunodeficiency virus, hepatitis C virus, and hepatitis B virus
Published in Anais da Academia Brasileira de Ciências (01-01-2022)“…The concern about the risks of viral infections transmission through blood transfusion has led into a search for improvements on screening tests used for the…”
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15
Physicochemical quality profiles of commercial oral tablets and capsules containing lutein - impact of insufficient specific sanitary regulations
Published in Anais da Academia Brasileira de Ciências (01-07-2018)“…Dietary supplements in many countries such as the USA do not require registration prior to commercialization. The Agência Nacional de Vigilância Sanitária…”
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16
Looking at the proteases from a simple perspective
Published in Journal of molecular recognition (01-03-2011)“…Proteases have received enormous interest from the research and medical communities because of their significant roles in several human diseases. Some examples…”
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Effects of a nanocomposite containing Orbignya speciosa lipophilic extract on Benign Prostatic Hyperplasia
Published in Journal of ethnopharmacology (26-04-2011)“…Lower urinary tract symptoms (LUTS) are a common complaint among aging men and are usually caused by Benign Prostatic Hyperplasia (BPH). A number of medical…”
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Antibacterial profile against drug-resistant Staphylococcus epidermidis clinical strain and structure-activity relationship studies of 1H-pyrazolo[3,4-b]pyridine and thieno[2,3-b]pyridine derivatives
Published in Bioorganic & medicinal chemistry (01-09-2008)“…Antibacterial resistance is a complex problem that contributes to health and economic losses worldwide. The Staphylococcus epidermidis is an important…”
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Preparation and characterization of polysaccharide-based nanoparticles with anticoagulant activity
Published in International journal of nanomedicine (01-01-2012)“…The aim of this study was to produce and characterize nanoparticles (NPs), combining chondroitin sulfate (CS) and fucoidan (FC) with chitosan for therapeutic…”
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In Silico studies of novel Sildenafil self-emulsifying drug delivery system absorption improvement for pulmonary arterial hypertension
Published in Anais da Academia Brasileira de Ciências (01-01-2020)“…Abstract Sildenafil is a potent selective inhibitor of phosphosdiesterase-5 previously used in erectile dysfunction and subsequently approved in 2005 for…”
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