Search Results - "C.-F. Perno"

Hepatitis C Virus Genetic Variability and the Presence of NS5B Resistance-Associated Mutations as Natural Polymorphisms in Selected Genotypes Could Affect the Response to NS5B Inhibitors by DI MAIO, V. C, CENTO, V, MIRABELLI, C, ARTESE, A, COSTA, G, ALCARO, S, PERNO, C. F, CECCHERINI-SILBERSTEIN, F

“…Because of the extreme genetic variability of hepatitis C virus (HCV), we analyzed the NS5B polymerase genetic variability in circulating HCV…”
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Two‐drug vs. three‐drug combinations for HIV‐1: Do we have enough data to make the switch? by Moreno, S, Perno, CF, Mallon, PW, Behrens, G, Corbeau, P, Routy, J‐P, Darcis, G

“…Three‐drug combination antiretroviral therapy (ART) became available in 1996, dramatically improving the prognosis of people living with HIV. The clinical…”
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Alarming rates of virological failure and HIV‐1 drug resistance amongst adolescents living with perinatal HIV in both urban and rural settings: evidence from the EDCTP READY‐study in Cameroon by Fokam, J, Takou, D, Njume, D, Pabo, W, Santoro, MM, Njom Nlend, A‐E, Beloumou, G, Sosso, S, Moudourou, S, Teto, G, Dambaya, B, Djupsa, S, Tetang Ndiang, S, Ateba, FN, Billong, SC, Kamta, C, Bala, L, Lambo, V, Tala, V, Chenwi Ambe, C, Mpouel, ML, Cappelli, G, Cham, F, Ndip, R, Mbuagbaw, L, Koki Ndombo, P, Ceccherini‐Silberstein, F, Colizzi, V, Perno, C‐F, Ndjolo, A

“…Objectives Adolescents living with perinatal HIV infection (ALPHI) experience persistently high mortality rates, particularly in resource‐limited settings. It…”
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The Management of Geriatric and Frail HIV Patients. A 2017 Update from the Italian Guidelines for the Use of Antiretroviral Agents and the Diagnostic Clinical Management of HIV-1 Infected Persons by Guaraldi, G, Marcotullio, S, Maserati, R, Gargiulo, M, Milic, J, Franconi, I, Chirianni, A, Andreoni, M, Galli, M, Lazzarin, A, D'Arminio Monforte, A, Di Perri, G, Perno, C-F, Puoti, M, Vella, S, Di Biagio, A, Maia, L, Mussi, C, Cesari, M, Antinori, A

“…This article deals with the attempt to join HIV and geriatric care management in the 2017 edition of the Italian guidelines for the use of antiretrovirals and…”
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Exploring nasopharyngeal microbiota profile in children affected by SARS-CoV-2 infection by Romani, L, Del Chierico, F, Pane, S, Ristori, M V, Pirona, I, Guarrasi, V, Cotugno, N, Bernardi, S, Lancella, L, Perno, C F, Rossi, P, Villani, A, Campana, A, Palma, P, Putignani, L

“…The relationship between COVID-19 and nasopharyngeal (NP) microbiota has been investigated mainly in the adult population. We explored the NP profile of…”
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Managing Haemophilia for Life: 4th Haemophilia Global Summit by Astermark, J., Dolan, G., Hilberg, T., Jiménez-Yuste, V., Laffan, M., Lassila, R., Lobet, S., Martinoli, C., Perno, C.-F.

“…Summary The 4th Haemophilia Global Summit was held in Potsdam, Germany, in September 2013 and brought together an international faculty of haemophilia experts…”
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Natural polymorphisms of HIV-1 subtype-C integrase coding region in a large group of ARV-naïve infected individuals by Dimonte, S., Babakir-Mina, M., Aquaro, S., Perno, C.-F.

“…Purpose Integrase (IN) is an enzyme produced by human immunodeficiency virus (HIV)-1 that enables its genetic material to be integrated into the DNA of the…”
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Efficacy of etravirine combined with darunavir or other ritonavir‐boosted protease inhibitors in HIV‐1‐infected patients: an observational study using pooled European cohort data by Vingerhoets, J, Calvez, V, Flandre, P, Marcelin, A‐G, Ceccherini‐Silberstein, F, Perno, C‐F, Mercedes Santoro, M, Bateson, R, Nelson, M, Cozzi‐Lepri, A, Grarup, J, Lundgren, J, Incardona, F, Kaiser, R, Sonnerborg, A, Clotet, B, Paredes, R, Günthard, HF, Ledergerber, B, Hoogstoel, A, Nijs, S, Tambuyzer, L, Lavreys, L, Opsomer, M

“…Objectives This observational study in antiretroviral treatment‐experienced, HIV‐1‐infected adults explored the efficacy of etravirine plus darunavir/ritonavir…”
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The use of human immunodeficiency virus resistance tests in clinical practice by Ceccherini-Silberstein, F., Cento, V., Calvez, V., Perno, C.-F.

“…Important progress has been made in recent years in the development and clinical use of drugs for the treatment of human immunodeficiency virus type 1 (HIV-1)…”
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Snapshot on drug-resistance rate and profiles in patients with chronic hepatitis B receiving nucleos(t)ide analogues in clinical practice by Salpini, R., Alteri, C., Cento, V., Pollicita, M., Micheli, V., Gubertini, G., De Sanctis, G.M., Visca, M., Romano, S., Sarrecchia, C., Andreoni, M., Angelico, M., Parruti, G., Svicher, V., Perno, C.F.

“…While the selection of complex HBV drug‐resistance patterns on therapeutic failure can compromise the efficacy of anti‐HBV therapies, recent data show that…”
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Performance evaluation of an in-house human immunodeficiency virus type-1 protease-reverse transcriptase genotyping assay in Cameroon by Fokam, J., Salpini, R., Santoro, M. M., Cento, V., D’Arrigo, R., Gori, C., Perno, C. F., Colizzi, V., Nanfack, A., Gwom, L. C., Cappelli, G., Takou, D.

“…Most commercial HIV-1 genotyping assays are hampered by high cost in resource-limited settings. Moreover, their performance might be influenced over time by…”
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Antiretrovirus Activity of a Novel Class of Acyclic Pyrimidine Nucleoside Phosphonates by BALZARINI, J, PANNECOUQUE, C, DE CLERCQ, E, AQUARO, S, PERNO, C.-F, EGBERINK, H, HOLY, A

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Prediction of response to antiretroviral therapy by human experts and by the EuResist data‐driven expert system (the EVE study) by Zazzi, M, Kaiser, R, Sönnerborg, A, Struck, D, Altmann, A, Prosperi, M, Rosen‐Zvi, M, Petroczi, A, Peres, Y, Schülter, E, Boucher, CA, Brun‐Vezinet, F, Harrigan, PR, Morris, L, Obermeier, M, Perno, C‐F, Phanuphak, P, Pillay, D, Shafer, RW, Vandamme, A‐M, van Laethem, K, Wensing, AMJ, Lengauer, T, Incardona, F

“…Objectives The EuResist expert system is a novel data‐driven online system for computing the probability of 8‐week success for any given pair of HIV‐1 genotype…”
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Characterization of drug-resistance mutations in HBV D-genotype chronically infected patients, naïve to antiviral drugs by Salpini, R., Svicher, V., Cento, V., Gori, C., Bertoli, A., Scopelliti, F., Micheli, V., Cappiello, T., Spanò, A., Rizzardini, G., De Sanctis, G.M., Sarrecchia, C., Angelico, M., Perno, C.F.

“…► Our study defined prevalence of drug-resistance in 140 drug-naïve patients. ► No YMDD mutations, rtM204V/I, were found. ► 1.4% of patients carried primary…”
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Virological response and resistance profile in HIV‐1‐infected patients starting darunavir‐containing regimens by Armenia, D, Di Carlo, D, Maffongelli, G, Borghi, V, Alteri, C, Forbici, F, Bertoli, A, Gori, C, Giuliani, M, Nicastri, E, Zaccarelli, M, Pinnetti, C, Cicalini, S, D'Offizi, G, Ceccherini‐Silberstein, F, Mussini, C, Antinori, A, Andreoni, M, Perno, CF, Santoro, MM

“…Objectives We evaluated the virological response in patients starting a regimen based on darunavir/ritonavir (DRV/r), which is currently the most widely used…”
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Human Immunodeficiency Virus-1 Viral Load Is Elevated in Individuals With Reverse-Transcriptase Mutation M184V/I During Virological Failure of First-Line Antiretroviral Therapy and Is Associated With Compensatory Mutation L74I by Gregson, J, Rhee, S Y, Datir, R, Pillay, D, Perno, C F, Derache, A, Shafer, R S, Gupta, R K

“…Abstract Background M184V/I cause high-level lamivudine (3TC) and emtricitabine (FTC) resistance and increased tenofovir disoproxil fumarate (TDF)…”
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Safety of nevirapine‐containing antiretroviral triple therapy regimens to prevent vertical transmission in an African cohort of HIV‐1‐infected pregnant women by Marazzi, MC, Germano, P, Liotta, G, Guidotti, G, Loureiro, S, Da Cruz Gomes, A, Valls Blazquez, MC, Narciso, P, Perno, CF, Mancinelli, S, Palombi, L

“…Objective To assess the incidence and consequences of adverse reactions among African HIV‐positive pregnant women treated with fixed‐dose combinations of a…”
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Mechanism of Anti-HIV Action of Masked Alaninyl d4T-Mp Derivatives by Balzarini, J., Karlsson, A., Aquaro, S., C.-F. Perno, Cahard, D., Naesens, L., De Clercq, E., McGuigan, C.

“…So324 is a 2′,3′-dideoxy-2$^{ \prime}$,3′-didehydrothymidine-5$^{ \prime}$-monophosphate (d4T-MP) prodrug containing at the phosphate moiety a phenyl group and…”
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Relative Potency of Protease Inhibitors in Monocytes/Macrophages Acutely and Chronically Infected with Human Immunodeficiency Virus by Perno, Carlo-Federico, Newcomb, Fonda M., Davis, David A., Aquaro, Stefano, Humphrey, Rachel W., Caliò, Raffaele, Yarchoan, Robert

“…The activity of three human immunodeficiency virus (HIV) protease inhibitors was investigated in human primary monocytes/macrophages (M/M) chronically infected…”
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Non-B HIV type 1 subtypes among men who have sex with men in Rome, Italy by Giuliani, M, Montieri, S, Palamara, G, Latini, A, Alteri, C, Perno, C F, Santoro, M M, Rezza, G, Ciccozzi, M

“…An increase in the circulation of HIV-1 non-B subtypes has been observed in recent years in Western European countries. Due to the lack of data on the…”
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