Search Results - "C. Roder"
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Separating two components of body image in anorexia nervosa using fMRI
Published in Psychological medicine (01-09-2010)“…Body image distortion is a key symptom of anorexia nervosa. In behavioral research two components of body image have been defined: attitudes towards the body…”
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2
The involvement of the NMDA receptor d-serine/glycine site in the pathophysiology and treatment of schizophrenia
Published in Neuroscience and biobehavioral reviews (01-02-2010)“…Hypofunction of the N-methyl- d-aspartate receptor (NMDAR) has been implicated in the pathophysiology of schizophrenia. The NMDAR contains a d-serine/glycine…”
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3
Behavioral Phenotypes of Disc1 Missense Mutations in Mice
Published in Neuron (Cambridge, Mass.) (03-05-2007)“…To support the role of DISC1 in human psychiatric disorders, we identified and analyzed two independently derived ENU-induced mutations in Exon 2 of mouse…”
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Superior outcomes of decompression with an interlaminar dynamic device versus decompression alone in patients with lumbar spinal stenosis and back pain: a cross registry study
Published in European spine journal (01-10-2015)“…Introduction Surgical decompression for lumbar spinal stenosis (LSS) has been associated with poorer outcomes in patients with pronounced low back pain (LBP)…”
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Maximizing the extent of resection and survival benefit of patients in glioblastoma surgery: High-field iMRI versus conventional and 5-ALA-assisted surgery
Published in European journal of surgical oncology (01-03-2014)“…Abstract Aims A safe total resection followed by adjuvant chemoradiotherapy should be the primary goal in the treatment of glioblastomas (GBMs) to enable…”
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A Dopamine D2 Receptor-DISC1 Protein Complex may Contribute to Antipsychotic-Like Effects
Published in Neuron (Cambridge, Mass.) (17-12-2014)“…Current antipsychotic drugs primarily target dopamine D2 receptors (D2Rs), in conjunction with other receptors such as those for serotonin. However, these…”
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Disrupted-In-Schizophrenia-1 (DISC1) interactome and mental disorders: Impact of mouse models
Published in Neuroscience and biobehavioral reviews (01-09-2014)“…Disrupted-In-Schizophrenia-1 (DISC1) has captured much attention because it predisposes individuals to a wide range of mental illnesses. Notably, a number of…”
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D-Serine Augments NMDA-NR2B Receptor-Dependent Hippocampal Long-Term Depression and Spatial Reversal Learning
Published in Neuropsychopharmacology (New York, N.Y.) (01-04-2008)“…The contributions of hippocampal long-term depression (LTD) to explicit learning and memory are poorly understood. Electrophysiological and behavioral studies…”
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9
Dynamic posterior stabilization for degenerative lumbar spine disease: a large consecutive case series with long-term follow-up by additional postal survey
Published in European spine journal (01-08-2016)“…Introduction Dynamic stabilization of the degenerated spine was invented to overcome the negative side effects of fusion surgery like adjacent segment…”
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Australasian Society of Infectious Diseases updated guidelines for the management of Clostridium difficile infection in adults and children in Australia and New Zealand
Published in Internal medicine journal (01-04-2016)“…The incidence of Clostridium difficile infection (CDI) continues to rise, whilst treatment remains problematic due to recurrent, refractory and potentially…”
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Synergistic interactions between PDE4B and GSK-3: DISC1 mutant mice
Published in Neuropharmacology (01-03-2012)“…Disrupted-In-Schizophrenia-1 (DISC1) is a strong genetic risk factor associated with psychiatric disorders. Two distinct mutations in the second exon of the…”
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Contributions of the d-serine pathway to schizophrenia
Published in Neuropharmacology (01-03-2012)“…The glutamate neurotransmitter system is one of the major candidate pathways for the pathophysiology of schizophrenia, and increased understanding of the…”
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Specific Inhibition of Phosphodiesterase-4B Results in Anxiolysis and Facilitates Memory Acquisition
Published in Neuropsychopharmacology (New York, N.Y.) (01-03-2016)“…Cognitive dysfunction is a core feature of dementia and a prominent feature in psychiatric disease. As non-redundant regulators of intracellular cAMP…”
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14
NCS-1 in the Dentate Gyrus Promotes Exploration, Synaptic Plasticity, and Rapid Acquisition of Spatial Memory
Published in Neuron (Cambridge, Mass.) (10-09-2009)“…The molecular underpinnings of exploration and its link to learning and memory remain poorly understood. Here we show that inducible, modest overexpression of…”
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Aiming for elimination: Outcomes of a consultation pathway supporting regional general practitioners to prescribe direct‐acting antiviral therapy for hepatitis C
Published in Journal of viral hepatitis (01-09-2018)“…Summary To increase access to treatment, the Australian government enabled general practitioners (GPs) to prescribe direct‐acting antivirals (DAAs) to treat…”
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16
Mania-like behavior induced by genetic dysfunction of the neuron-specific Na+,K+-ATPase α3 sodium pump
Published in Proceedings of the National Academy of Sciences - PNAS (01-11-2011)“…Bipolar disorder is a debilitating psychopathology with unknown etiology. Accumulating evidence suggests the possible involvement of Na+,K+-ATPase dysfunction…”
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A mouse model of Down syndrome trisomic for all human chromosome 21 syntenic regions
Published in Human molecular genetics (15-07-2010)“…Down syndrome (DS) is caused by the presence of an extra copy of human chromosome 21 (Hsa21) and is the most common genetic cause for developmental cognitive…”
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Meta-analysis of microarray gene expression studies on intracranial aneurysms
Published in Neuroscience (10-01-2012)“…Abstract The rupture of intracranial aneurysms (IAs) is one of the most devastating neurological conditions known to date. Although treatment has changed…”
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Chemical Induction of mGluR5- and Protein Synthesis-Dependent Long-Term Depression in Hippocampal Area CA1
Published in Journal of neurophysiology (01-07-2001)“… 1 Department of Neuroscience, Howard Hughes Medical Institute, Brown University, Providence, Rhode Island 02912; and 2 Program in Developmental and Fetal…”
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The Receptor Tyrosine Kinase EphB2 Regulates NMDA-Dependent Synaptic Function
Published in Neuron (Cambridge, Mass.) (20-12-2001)“…Members of the Eph family of receptor tyrosine kinases control many aspects of cellular interactions during development, including axon guidance. Here, we…”
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