Search Results - "C. Freda"

Clinopyroxene–liquid thermometers and barometers specific to alkaline differentiated magmas by Masotta, M., Mollo, S., Freda, C., Gaeta, M., Moore, G.

“…We present new thermometers and barometers based on clinopyroxene–liquid equilibria specific to alkaline differentiated magmas. The new models were calibrated…”
Get full text

Achieving an Optimal T g Change by Elucidating the Polymer–Nanoparticle Interface: A Molecular Dynamics Simulation Study of the Poly(vinyl alcohol)–Silica Nanocomposite System by Chakraborty, Souvik, Lim, Freda C. H, Ye, Jun

“…The glass-transition temperature (T g) of a polymer–nanoparticle composite system is strongly dependent on the local segmental dynamics of the polymers. These…”
Get full text

Interfacial Properties and Monolayer Collapse of Alkyl Benzenesulfonate Surfactant Monolayers at the Decane–Water Interface from Molecular Dynamics Simulations by Tan, Jacqueline S. J, Zhang, Liping, Lim, Freda C. H, Cheong, Daniel W

“…The molecular structure of a surfactant molecule is known to have a great effect on the interfacial properties and the type of nanostructures formed. In this…”
Get full text

Multidisciplinary Approaches Identify Compounds that Bind to Human ACE2 or SARS-CoV-2 Spike Protein as Candidates to Block SARS-CoV-2-ACE2 Receptor Interactions by Day, Christopher J, Bailly, Benjamin, Guillon, Patrice, Dirr, Larissa, Jen, Freda E-C, Spillings, Belinda L, Mak, Johnson, von Itzstein, Mark, Haselhorst, Thomas, Jennings, Michael P

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a recently emerged virus that causes coronavirus infectious disease 2019 (COVID-19). SARS-CoV-2…”
Get full text

The biosynthesis and role of phosphorylcholine in pathogenic and nonpathogenic bacteria by Zhang, Yuan, Jen, Freda E.-C., Fox, Kate L., Edwards, Jennifer L., Jennings, Michael P.

“…Phosphorylcholine (ChoP) is found in a variety of prokaryotic and eukaryotic organisms. It is now recognized as a critical modification of the surface…”
Get full text

Atomistic Characterization of Healthy and Damaged Hair Surfaces: A Molecular Dynamics Simulation Study of Fatty Acids on Protein Layer by Wang, Qiang, Phang, Jia Min, Chakraborty, Souvik, Zhang, Liling, Klähn, Marco, Nalaparaju, Anjaiah, Lim, Freda C. H.

“…Amid the bourgeoning demand for in‐silico designed, environmentally sustainable, and highly effective hair care formulations, a growing interest is evident in…”
Get full text

Fight against postoperative pulmonary complications: ways to anticipate by RICHA, Freda C., HARB, Sarah K.

Get full text

The phospholipase A of Neisseria gonorrhoeae lyses eukaryotic membranes and is necessary for survival in neutrophils and cervical epithelial cells by Apicella, Michael A, Edwards, Jennifer L, Ketterer, Margaret R, Weiss, David S, Zhang, Yuan, Jen, Freda E-C, Jennings, Michael P

“…Contact-dependent hemolysins are virulence factors in a number of human pathogens, including entero-invasive and . Here we demonstrate that produces an outer…”
Get full text

A Mechanistic Study on the Hydrolysis of Cyclic Ketene Acetal (CKA) and Proof of Concept of Polymerization in Water by Mothe, Srinivasa Reddy, Chennamaneni, Lohitha Rao, Tan, Jacqueline, Lim, Freda C. H., Zhao, Wenguang, Thoniyot, Praveen

“…The present work systematically investigates the hydrolysis mechanism of cyclic ketene acetal (CKA) monomers in detail and explores polymerization in water…”
Get full text

Neisseria gonorrhoeae pilin glycan contributes to CR3 activation during challenge of primary cervical epithelial cells by Jennings, Michael P., Jen, Freda E.‐C., Roddam, Louise F., Apicella, Michael A., Edwards, Jennifer L.

“…Summary Expression of type IV pili by Neisseria gonorrhoeae plays a critical role in mediating adherence to human epithelial cells. Gonococcal pilin is…”
Get full text

Myocarditis Associated with Immune Checkpoint Inhibitors: An Expert Consensus on Data Gaps and a Call to Action by Neilan, Tomas G., Rothenberg, Mace L., Amiri‐Kordestani, Laleh, Sullivan, Ryan J., Steingart, Richard M., Gregory, William, Hariharan, Subramanian, Hammad, Tarek A., Lindenfeld, JoAnn, Murphy, Martin J., Moslehi, Javid J., Abdullah, Hesham, Amiri‐Kordestani, Laleh, Bakker, Cecilia, Boshoff, Chris, Bringhurst, Charlie, Bucktrout, Samantha, Carlin, Kathleen, Caubel, Patrick, Chen, Roland, Chin, Kevin, Chudnovsky, Aleksander, Davis, John, Deutsch, Jonathan, Dixit, Rakesh, Gottfridsson, Christer, Gregory, William, Hammad, Tarek A., Handelsman, Dave, Hariharan, Subramanian, Holmes, William, Honig, Peter, Hugh‐Jones, Charles, Kaufman, Howard, Khan, Nasir, Kozono, David, Kwan, Antonia, Lewis‐Hall, Freda C., Ley‐Acosta, Sergio, Lindenfeld, JoAnn, Michelon, Elisabete, Moslehi, Javid J., Murphy, Martin J., Neilan, Tomas G., Patel, Mayur, Pavlovic, Dejan, Pignatti, Francesco, Potter, Jonathan, Reese, David, Rothenberg, Mace L., Safferman, Allan, Silvester, Eliza, Steingart, Richard M., Sullivan, Ryan J., Zhou, Ming

“…Immune checkpoint inhibitors (ICIs) have transformed the treatment landscape for cancer. Due to the mechanism of action of ICIs, inflammatory reactions against…”
Get full text

Phase variation of DNA methyltransferases and the regulation of virulence and immune evasion in the pathogenic Neisseria by Seib, Kate L., Jen, Freda E.-C., Scott, Adeana L., Tan, Aimee, Jennings, Michael P.

“…Abstract The pathogenic Neisseria provide textbook examples of phase variation: the high frequency, random and reversible switching of gene expression…”
Get full text

The dCache Chemoreceptor TlpA of Helicobacter pylori Binds Multiple Attractant and Antagonistic Ligands via Distinct Sites by Johnson, Kevin S, Elgamoudi, Bassam A, Jen, Freda E-C, Day, Christopher J, Sweeney, Emily Goers, Pryce, Megan L, Guillemin, Karen, Haselhorst, Thomas, Korolik, Victoria, Ottemann, Karen M

“…The Helicobacter pylori chemoreceptor TlpA plays a role in dampening host inflammation during chronic stomach colonization. TlpA has a periplasmic dCache_1…”
Get full text

A biphasic epigenetic switch controls immunoevasion, virulence and niche adaptation in non-typeable Haemophilus influenzae by Atack, John M., Srikhanta, Yogitha N., Fox, Kate L., Jurcisek, Joseph A., Brockman, Kenneth L., Clark, Tyson A., Boitano, Matthew, Power, Peter M., Jen, Freda E.-C., McEwan, Alastair G., Grimmond, Sean M., Smith, Arnold L., Barenkamp, Stephen J., Korlach, Jonas, Bakaletz, Lauren O., Jennings, Michael P.

“…Non-typeable Haemophilus influenzae contains an N 6 -adenine DNA-methyltransferase (ModA) that is subject to phase-variable expression (random ON/OFF…”
Get full text

Phasevarions Mediate Epigenetic Regulation of Antimicrobial Susceptibility in Neisseria meningitidis by JEN, Freda E.-C, SEIB, Kate L, JENNINGS, Michael P

“…Phase variation is a common feature of host-adapted bacterial pathogens such as Neisseria meningitidis. Recently, we reported that this rapid on/off switching…”
Get full text

Elucidating the Role of Interfacial Hydrogen Bonds on Glass Transition Temperature Change in a Poly(Vinyl Alcohol)/SiO2 Polymer‐Nanocomposite by Noncovalent Interaction Characterization and Atomistic Molecular Dynamics Simulations by Panigrahi, Ritwik, Chakraborty, Souvik, Ye, Jun, Lim, Geraldine S., Lim, Freda C. H., Yam, Joachim Khin Hun, Wu, Linda Yongling, Chng, Shuyun, Prawirasatya, Melissa, Herk, Alexander M., Thoniyot, Praveen

“…A thorough experimental investigation of polymer‐glass transition temperature (Tg) is performed on poly(vinyl alcohol) (PVA) and fumed silica nanoparticle…”
Get full text

ModM DNA methyltransferase methylome analysis reveals a potential role for Moraxella catarrhalis phasevarions in otitis media by Blakeway, Luke V., Power, Peter M., Jen, Freda E.‐C., Worboys, Sam R., Boitano, Matthew, Clark, Tyson A., Korlach, Jonas, Bakaletz, Lauren O., Jennings, Michael P., Peak, Ian R., Seib, Kate L.

“…Moraxella catarrhalis is a significant cause of otitis media and exacerbations of chronic obstructive pulmonary disease. Here, we characterize a phase‐variable…”
Get full text

Skarn xenolith record crustal CO2 liberation during Pompeii and Pollena eruptions, Vesuvius volcanic system, central Italy by Jolis, E.M., Troll, V.R., Harris, C., Freda, C., Gaeta, M., Orsi, G., Siebe, C.

“…Limestone assimilation and skarn formation are important processes in magmatic systems emplaced within carbonate-rich crust and can affect the composition of…”
Get full text

Glycointeractome of Neisseria gonorrhoeae: Identification of Host Glycans Targeted by the Gonococcus To Facilitate Adherence to Cervical and Urethral Epithelial Cells by Semchenko, Evgeny A, Everest-Dass, Arun V, Jen, Freda E-C, Mubaiwa, Tsitsi D, Day, Christopher J, Seib, Kate L

“…is a significant threat to global health for which a vaccine and novel treatment options are urgently needed. Glycans expressed by human cells are commonly…”
Get full text

Epigenetic Regulation Alters Biofilm Architecture and Composition in Multiple Clinical Isolates of Nontypeable Haemophilus influenzae by Brockman, Kenneth L, Azzari, Patrick N, Branstool, M Taylor, Atack, John M, Schulz, Benjamin L, Jen, Freda E-C, Jennings, Michael P, Bakaletz, Lauren O

“…Biofilms play a critical role in the colonization, persistence, and pathogenesis of many human pathogens. Multiple mucosa-associated pathogens have evolved a…”
Get full text