Search Results - "Černý, Jiří"

Benchmark database of accurate (MP2 and CCSD(T) complete basis set limit) interaction energies of small model complexes, DNA base pairs, and amino acid pairs by Jurecka, Petr, Sponer, Jirí, Cerný, Jirí, Hobza, Pavel

“…MP2 and CCSD(T) complete basis set (CBS) limit interaction energies and geometries for more than 100 DNA base pairs, amino acid pairs and model complexes are…”
Get more information

Isotopic Depletion Increases the Spatial Resolution of FPOP Top-Down Mass Spectrometry Analysis by Polák, Marek, Černý, Jiří, Novák, Petr

“…Protein radical labeling, like fast photochemical oxidation of proteins (FPOP), coupled to a top-down mass spectrometry (MS) analysis offers an alternative…”
Get full text

Mapping the potential distribution of the principal vector of Crimean-Congo haemorrhagic fever virus Hyalomma marginatum in the Old World by Celina, Seyma S, Černý, Jiří, Samy, Abdallah M

“…Crimean-Congo haemorrhagic fever (CCHF) is the most widely distributed tick-borne viral disease in humans and is caused by the Crimean-Congo haemorrhagic fever…”
Get full text

On the Structure and Geometry of Biomolecular Binding Motifs (Hydrogen-Bonding, Stacking, X−H···π): WFT and DFT Calculations by Riley, Kevin E, Pitoňák, Michal, Černý, Jiří, Hobza, Pavel

“…The strengths of noncovalent interactions are generally very sensitive to a number of geometric parameters. Among the most important of these parameters is the…”
Get full text

Double-Helical → Ladder Structural Transition in the B-DNA is Induced by a Loss of Dispersion Energy by Černý, Jiří, Kabeláč, Martin, Hobza, Pavel

“…The role of the dispersion energy and electrostatic energy on the geometry and stability of the B-DNA helix was investigated. Both molecular dynamics…”
Get full text

Bioinformatic analysis of the protein/DNA interface by Schneider, Bohdan, Cerný, Jirí, Svozil, Daniel, Cech, Petr, Gelly, Jean-Christophe, de Brevern, Alexandre G

“…To investigate the principles driving recognition between proteins and DNA, we analyzed more than thousand crystal structures of protein/DNA complexes. We…”
Get full text

A DNA structural alphabet provides new insight into DNA flexibility by Schneider, Bohdan, Božíková, Paulína, Nečasová, Iva, Čech, Petr, Svozil, Daniel, Černý, Jiří

“…DNA is a structurally plastic molecule, and its biological function is enabled by adaptation to its binding partners. To identify the DNA structural…”
Get full text

Nucleoside inhibitors of tick-borne encephalitis virus by Eyer, Luděk, Valdés, James J, Gil, Victor A, Nencka, Radim, Hřebabecký, Hubert, Šála, Michal, Salát, Jiří, Černý, Jiří, Palus, Martin, De Clercq, Erik, Růžek, Daniel

“…Tick-borne encephalitis virus (TBEV) is a leading cause of human neuroinfections in Europe and Northeast Asia. There are no antiviral therapies for treating…”
Get full text

Roles of Octabutoxy Substitution and J‑Aggregation in Stabilization of the Excited State in Nickel Phthalocyanine by Rais, David, Toman, Petr, Černý, Jiří, Menšík, Miroslav, Pfleger, Jiří

“…Nickel phthalocyanine (NiPc) complexes are known to show a rapid nonradiative deactivation of the photoexcited state through the internal conversion. This…”
Get full text

Evolution of tertiary structure of viral RNA dependent polymerases by Černý, Jiří, Černá Bolfíková, Barbora, Valdés, James J, Grubhoffer, Libor, Růžek, Daniel

“…Viral RNA dependent polymerases (vRdPs) are present in all RNA viruses; unfortunately, their sequence similarity is too low for phylogenetic studies…”
Get full text

Engineering PD-1-targeted small protein variants for in vitro diagnostics and in vivo PET imaging by Mierzwicka, Joanna Maria, Petroková, Hana, Kafková, Leona Rašková, Kosztyu, Petr, Černý, Jiří, Kuchař, Milan, Petřík, Miloš, Bendová, Kateřina, Krasulová, Kristýna, Groza, Yaroslava, Vaňková, Lucie, Bharadwaj, Shiv, Panova, Natalya, Křupka, Michal, Škarda, Jozef, Raška, Milan, Malý, Petr

“…Programmed cell death 1 (PD-1) belongs to immune checkpoint proteins ensuring negative regulation of the immune response. In non-small cell lung cancer…”
Get full text

The crystal structure of XdpB, the bacterial old yellow enzyme, in an FMN-free form by Zahradník, Jiří, Kolenko, Petr, Palyzová, Andrea, Černý, Jiří, Kolářová, Lucie, Kyslíková, Eva, Marešová, Helena, Grulich, Michal, Nunvar, Jaroslav, Šulc, Miroslav, Kyslík, Pavel, Schneider, Bohdan

“…Old Yellow Enzymes (OYEs) are NAD(P)H dehydrogenases of not fully resolved physiological roles that are widespread among bacteria, plants, and fungi and have a…”
Get full text

p19-Targeting ILP Protein Blockers of IL-23/Th-17 Pro-Inflammatory Axis Displayed on Engineered Bacteria of Food Origin by Škrlec, Katja, Zadravec, Petra, Hlavničková, Marie, Kuchař, Milan, Vaňková, Lucie, Petroková, Hana, Křížová, Lucie, Černý, Jiří, Berlec, Aleš, Malý, Petr

“…IL-23-mediated Th-17 cell activation and stimulation of IL-17-driven pro-inflammatory axis has been associated with autoimmunity disorders such as Inflammatory…”
Get full text

Human IL-22 receptor-targeted small protein antagonist suppress murine DSS-induced colitis by Kuchař, Milan, Sloupenská, Kristýna, Rašková Kafková, Leona, Groza, Yaroslava, Škarda, Jozef, Kosztyu, Petr, Hlavničková, Marie, Mierzwicka, Joanna M, Osička, Radim, Petroková, Hana, Walimbwa, Stephen I, Bharadwaj, Shiv, Černý, Jiří, Raška, Milan, Malý, Petr

“…Human interleukin-22 (IL-22) is known as a "dual function" cytokine that acts as a master regulator to maintain homeostasis, structural integrity of the…”
Get full text

Local dynamics of proteins and DNA evaluated from crystallographic B factors by Schneider, Bohdan, Gelly, Jean-Christophe, de Brevern, Alexandre G., Černý, Jiří

“…The dynamics of protein and nucleic acid structures is as important as their average static picture. The local molecular dynamics concealed in diffraction…”
Get full text

First Detection of SARS-CoV-2 in White Rhinoceros during a Small-Scale Coronavirus Surveillance in the Bandia Reserve, Senegal by Italiya, Jignesh, Vacek, Vojtěch, Matějů, Petr, Dering, Christophe, Celina, Seyma S., Ndiaye, Arame, Černý, Jiří

“…The SARS-CoV-2 pandemic has heightened interest in the monitoring and surveillance of coronaviruses in wildlife. Testing for the virus in animals can provide…”
Get full text

Ixodes scapularis saliva components that elicit responses associated with acquired tick-resistance by Narasimhan, Sukanya, Kurokawa, Cheyne, Diktas, Husrev, Strank, Norma Olivares, Černý, Jiří, Murfin, Kristen, Cao, Yongguo, Lynn, Geoff, Trentleman, Jos, Wu, Ming-Jie, DePonte, Kathy, Kantor, Fred, Anguita, Juan, Hovius, Joppe, Fikrig, Erol

“…Ticks and tick-borne diseases are on the rise world-wide and vaccines to prevent transmission of tick-borne diseases is an urgent public health need. Tick…”
Get full text

Small protein blockers of human IL-6 receptor alpha inhibit proliferation and migration of cancer cells by Groza, Yaroslava, Lacina, Lukáš, Kuchař, Milan, Rašková Kafková, Leona, Zachová, Kateřina, Janoušková, Olga, Osička, Radim, Černý, Jiří, Petroková, Hana, Mierzwicka, Joanna Maria, Panova, Natalya, Kosztyu, Petr, Sloupenská, Kristýna, Malý, Jan, Škarda, Jozef, Raška, Milan, Smetana, Jr, Karel, Malý, Petr

“…Interleukin-6 (IL-6) is a multifunctional cytokine that controls the immune response, and its role has been described in the development of autoimmune…”
Get full text

Myomedin replicas of gp120 V3 loop glycan epitopes recognized by PGT121 and PGT126 antibodies as non-cognate antigens for stimulation of HIV-1 broadly neutralizing antibodies by Daniel Lišková, Veronika, Kosztyu, Petr, Kuchař, Milan, Černý, Jiří, Bharadwaj, Shiv, Petroková, Hana, Vroblová, Eliška, Křupka, Michal, Malý, Michal, Zosinčuková, Tereza, Šulc, Josef, Rašková Kafková, Leona, Raška, Milan, Malý, Petr

“…Imprinting broadly neutralizing antibody (bNAb) paratopes by shape complementary protein mimotopes represents a potential alternative for developing vaccine…”
Get full text

ABD-Derived Protein Blockers of Human IL-17 Receptor A as Non-IgG Alternatives for Modulation of IL-17-Dependent Pro-Inflammatory Axis by Hlavničková, Marie, Kuchař, Milan, Osička, Radim, Vaňková, Lucie, Petroková, Hana, Malý, Michal, Černý, Jiří, Arenberger, Petr, Malý, Petr

“…Interleukin 17 (IL-17) and its cognate receptor A (IL-17RA) play a crucial role in Th17 cells-mediated pro-inflammatory pathway and pathogenesis of several…”
Get full text