Search Results - "Côte, Marjorie"
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Inherited defects in lymphocyte cytotoxic activity
Published in Immunological reviews (01-05-2010)“…The granule-dependent cytotoxic activity of lymphocytes plays a critical role in the defense against virally infected cells and tumor cells. The importance of…”
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2
Interaction between the prefrontal and visual cortices supports subjective fear
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (26-08-2024)“…It has been reported that threatening and non-threatening visual stimuli can be distinguished based on the multi-voxel patterns of haemodynamic activity in the…”
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3
Munc18-2 deficiency causes familial hemophagocytic lymphohistiocytosis type 5 and impairs cytotoxic granule exocytosis in patient NK cells
Published in The Journal of clinical investigation (01-12-2009)“…Familial hemophagocytic lymphohistiocytosis (FHL) is a genetically heterogeneous autosomal recessive immune disorder characterized by the occurrence of…”
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4
LYST Controls the Biogenesis of the Endosomal Compartment Required for Secretory Lysosome Function
Published in Traffic (Copenhagen, Denmark) (01-02-2015)“…Chediak–Higashi syndrome (CHS) is caused by mutations in the gene encoding LYST protein, the function of which remains poorly understood. Prominent features of…”
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5
Distinct severity of HLH in both human and murine mutants with complete loss of cytotoxic effector PRF1, RAB27A, and STX11
Published in Blood (24-01-2013)“…Inherited defects of granule-dependent cytotoxicity led to the life-threatening immune disorder hemophagocytic lymphohistiocytosis (HLH), characterized by…”
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6
Development of small molecule inhibitors of natural killer group 2D receptor (NKG2D)
Published in Bioorganic & medicinal chemistry letters (15-11-2023)“…[Display omitted] Natural killer group 2D (NKG2D) is a homodimeric activating immunoreceptor whose function is to detect and eliminate compromised cells upon…”
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7
Identification of small-molecule protein-protein interaction inhibitors for NKG2D
Published in Proceedings of the National Academy of Sciences - PNAS (02-05-2023)“…NKG2D (natural-killer group 2, member D) is a homodimeric transmembrane receptor that plays an important role in NK, γδ , and CD8 T cell-mediated immune…”
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SLAT promotes TCR-mediated, Rap1-dependent LFA-1 activation and adhesion through interaction of its PH domain with Rap1
Published in Journal of cell science (01-12-2015)“…SLAT (also known as DEF6) promotes T cell activation and differentiation by regulating NFAT-Ca(2+) signaling. However, its role in TCR-mediated inside-out…”
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9
Distinct severity of HLH in both human and murine mutants with complete loss of cytotoxic effector PRF1, RAB27A, and STX11
Published in Journal of allergy and clinical immunology (21-03-2013)“…Inherited defects of granule-dependent cytotoxicity led to the life-threatening immune disorder hemophagocytic lymphohistiocytosis (HLH), characterized by…”
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10
Interaction Between the Prefrontal and Visual Cortices Supports Subjective Fear
Published in Journal of vision (Charlottesville, Va.) (15-09-2024)Get full text
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11
Inpatient Physical Therapy in Moderate to Severe Traumatic Brain Injury in in Older Adults: A Scoping Review
Published in International journal of environmental research and public health (14-02-2023)“…Around 500/100,000 Canadians experience a traumatic brain injury (TBI) resulting in long-term disabilities and premature death. Physiotherapy is known to…”
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12
SLAT promotes TCR-mediated, Rap1-dependent LFA-1 activation and adhesion through interaction of its PH domain with Rap1
Published in The Journal of immunology (1950) (01-05-2016)“…Abstract SLAT (also known as DEF6) promotes T cell activation and differentiation by regulating NFAT-Ca2+ signaling. However, its role in TCR-mediated…”
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13
When excessive cost savings measurement drowns the objectives
Published in Journal of purchasing and supply management (01-06-2008)“…This paper presents the dynamics and complexity of implementing a cost savings measurement system in purchasing. It focuses on the technical and strategic…”
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14
Inherited defects in lymphocyte cytotoxic activity: Cytotoxic Cells
Published in Immunological reviews (2010)Get full text
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15
Detecting Cyanosis in Children
Published in Anesthesiology (Philadelphia) (01-07-1988)Get full text
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