Search Results - "Cécile Hilaire"
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Spinal Motoneuron TMEM16F Acts at C-boutons to Modulate Motor Resistance and Contributes to ALS Pathogenesis
Published in Cell reports (Cambridge) (25-02-2020)“…Neuronal Ca2+ entry elicited by electrical activity contributes to information coding via activation of K+ and Cl− channels. While Ca2+-dependent K+ channels…”
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Expression of ALS-linked SOD1 Mutation in Motoneurons or Myotubes Induces Differential Effects on Neuromuscular Function In vitro
Published in Neuroscience (21-05-2020)“…•Myotubes expressing the ALS-causing SOD1 mutant show reduced contraction frequency.•The presence of mutated SOD1 in myotube leads to reduced levels of the…”
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The Secretome of Human Dental Pulp Stem Cells and Its Components GDF15 and HB-EGF Protect Amyotrophic Lateral Sclerosis Motoneurons against Death
Published in Biomedicines (30-07-2023)“…Amyotrophic lateral sclerosis (ALS) is a fatal and incurable paralytic disorder caused by the progressive death of upper and lower motoneurons. Although…”
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4
KCC3-dependent chloride extrusion in adult sensory neurons
Published in Molecular and cellular neuroscience (01-07-2012)“…The cation–Cl− cotransporters participate to neuronal Cl− balance and are responsible for the post-natal Cl− switch in central neurons. In the adult peripheral…”
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5
Myotube elasticity of an amyotrophic lateral sclerosis mouse model
Published in Scientific reports (12-04-2018)“…Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that affects the motor system leading to generalized paralysis and death of patients…”
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Differential effect of Fas activation on spinal muscular atrophy motoneuron death and induction of axonal growth
Published in Cellular and Molecular Biology (31-10-2023)Get full text
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7
NKCC1 Phosphorylation Stimulates Neurite Growth of Injured Adult Sensory Neurons
Published in The Journal of neuroscience (20-06-2007)“…Peripheral nerve section promotes regenerative, elongated neuritic growth of adult sensory neurons. Although the role of chloride homeostasis, through the…”
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Best1 Is a Gene Regulated by Nerve Injury and Required for Ca2+-Activated Cl- Current Expression in Axotomized Sensory Neurons
Published in The Journal of neuroscience (12-08-2009)“…We investigated the molecular determinants of Ca(2+)-activated chloride current (CaCC) expressed in adult sensory neurons after a nerve injury. Dorsal root…”
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9
The Secretome of Human Dental Pulp Stem Cells and Its Components GDF15 and HB-EGF Protect Amyotrophic Lateral Sclerosis Motoneurons against Death
Published in Biomedicines (30-07-2023)“…Amyotrophic lateral sclerosis (ALS) is a fatal and incurable paralytic disorder caused by the progressive death of upper and lower motoneurons. Although…”
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10
Neurotrophin-4 modulates the mechanotransducer Cav3.2 T-type calcium current in mice down-hair neurons
Published in Biochemical journal (01-01-2012)“…The T-type Ca2+ channel Cav3.2 is expressed in nociceptive and mechanosensitive sensory neurons. The mechanosensitive D-hair (down-hair) neurons, which…”
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11
Calcium dependence of axotomized sensory neurons excitability
Published in Neuroscience letters (03-06-2005)“…Hyperexcitability of axotomized dorsal root ganglion neurons is thought to play a role in neuropathic pain. Numerous changes in ionic channels expression or…”
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12
Best1 Is a Gene Regulated by Nerve Injury and Required for Ca 2+ -Activated Cl − Current Expression in Axotomized Sensory Neurons
Published in The Journal of neuroscience (12-08-2009)“…We investigated the molecular determinants of Ca 2+ -activated chloride current (CaCC) expressed in adult sensory neurons after a nerve injury. Dorsal root…”
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13
K(+) current regulates calcium-activated chloride current-induced after depolarization in axotomized sensory neurons
Published in The European journal of neuroscience (01-09-2005)“…One of the major electrophysiological effects of axotomy is a hyperexcitability of injured afferents that is thought to be involved in peripheral neuropathic…”
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14
The Cav3.2/alpha1H T-type Ca2+ current is a molecular determinant of excitatory effects of GABA in adult sensory neurons
Published in Molecular and cellular neuroscience (01-10-2007)“…In addition to its inhibitory action, reports have shown that, in sensory neurons, GABA can be responsible for excitatory effects leading to painful behavior…”
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15
The Cav3.2/α1H T-type Ca2+ current is a molecular determinant of excitatory effects of GABA in adult sensory neurons
Published in Molecular and cellular neuroscience (01-10-2007)Get full text
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16
Novel roles for voltage‐gated T‐type Ca2+ and ClC‐2 channels in phagocytosis and angiogenic factor balance identified in human iPSC‐derived RPE
Published in The FASEB journal (01-04-2021)“…Human‐induced pluripotent stem cell (hiPSC)‐derived retinal pigment epithelium (RPE) is a powerful tool for pathophysiological studies and preclinical…”
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17
K+ current regulates calcium-activated chloride current-induced afterdepolarization in axotomized sensory neurons
Published in The European journal of neuroscience (01-09-2005)“…One of the major electrophysiological effects of axotomy is a hyperexcitability of injured afferents that is thought to be involved in peripheral neuropathic…”
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18
Novel roles for voltage-gated T-type Ca 2+ and ClC-2 channels in phagocytosis and angiogenic factor balance identified in human iPSC-derived RPE
Published in The FASEB journal (01-04-2021)“…Human-induced pluripotent stem cell (hiPSC)-derived retinal pigment epithelium (RPE) is a powerful tool for pathophysiological studies and preclinical…”
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19
The Cav3.2/α1H T-type Ca 2+ current is a molecular determinant of excitatory effects of GABA in adult sensory neurons
Published in Molecular and cellular neuroscience (2007)“…In addition to its inhibitory action, reports have shown that, in sensory neurons, GABA can be responsible for excitatory effects leading to painful behavior…”
Get full text
Journal Article -
20
NKCC1 Phosphorylation Stimulates Neurite Growth of Injured Adult Sensory Neurons: NKCC1 and regenerative growth
Published in The Journal of neuroscience (2007)“…Peripheral nerve section promotes regenerative, elongated neuritic growth of adult sensory neurons. While the role of chloride homeostasis, through the…”
Get full text
Journal Article