Search Results - "Cândido, Elizabete S."
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1
Computer-Aided Design of Antimicrobial Peptides: Are We Generating Effective Drug Candidates?
Published in Frontiers in microbiology (22-01-2020)“…Antimicrobial peptides (AMPs), especially antibacterial peptides, have been widely investigated as potential alternatives to antibiotic-based therapies…”
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2
Snake venom cathelicidins as natural antimicrobial peptides
Published in Frontiers in pharmacology (2019)“…Copyright © 2019 de Barros, Gonçalves, Cardoso, Santos, Franco and Cândido. This is an open-access article distributed under the terms of the Creative Commons…”
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3
Comparative transcriptome analyses of magainin I-susceptible and -resistant Escherichia coli strains
Published in Microbiology (Society for General Microbiology) (01-11-2018)“…Antimicrobial peptides (AMPs) have attracted considerable attention because of their multiple and complex mechanisms of action toward resistant bacteria…”
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4
Comparative NanoUPLC-MSE analysis between magainin I-susceptible and -resistant Escherichia coli strains
Published in Scientific reports (23-06-2017)“…In recent years the antimicrobial peptides (AMPs) have been prospected and designed as new alternatives to conventional antibiotics. Indeed, AMPs have…”
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The Structure/Function Relationship in Antimicrobial Peptides: What Can we Obtain From Structural Data?
Published in Advances in protein chemistry and structural biology (2018)“…Antimicrobial peptides (AMPs) have been widely isolated from most organisms in nature. This class of antimicrobials may undergo changes in their sequence for…”
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Computer-Aided Design of Mastoparan-like Peptides Enables the Generation of Nontoxic Variants with Extended Antibacterial Properties
Published in Journal of medicinal chemistry (12-09-2019)“…Diverse peptides have been evaluated for their activity against pathogenic microorganisms. Here, five mastoparan variants were designed based on mastoparan-L,…”
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Peptide PaDBS1R6 has potent antibacterial activity on clinical bacterial isolates and integrates an immunomodulatory peptide fragment within its sequence
Published in Biochimica et biophysica acta. General subjects (01-11-2024)“…Resistant infectious diseases caused by gram-negative bacteria are among the most serious worldwide health problems. Antimicrobial peptides (AMPs) have been…”
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An N-capping asparagine-lysine-proline (NKP) motif contributes to a hybrid flexible/stable multifunctional peptide scaffold
Published in Chemical science (Cambridge) (17-08-2022)“…Structural diversity drives multiple biological activities and mechanisms of action in linear peptides. Here we describe an unusual N-capping…”
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Short Cationic Peptide Derived from Archaea with Dual Antibacterial Properties and Anti-Infective Potential
Published in ACS infectious diseases (12-07-2019)“…Bacterial biofilms and associated infections represent one of the biggest challenges in the clinic, and as an alternative to counter bacterial infections,…”
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An acidic model pro-peptide affects the secondary structure, membrane interactions and antimicrobial activity of a crotalicidin fragment
Published in Scientific reports (24-07-2018)“…In order to study how acidic pro-peptides inhibit the antimicrobial activity of antimicrobial peptides, we introduce a simple model system, consisting of a 19…”
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A Computationally Designed Peptide Derived from Escherichia coli as a Potential Drug Template for Antibacterial and Antibiofilm Therapies
Published in ACS infectious diseases (14-12-2018)“…Computer-aided screening of antimicrobial peptides (AMPs) is a promising approach for discovering novel therapies against multidrug-resistant bacterial…”
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Xanthomonas gardneri exoenzymatic activity towards plant tissue
Published in World journal of microbiology & biotechnology (01-02-2008)“…Bacterial spot caused by Xanthomonas spp. is an important tomato and pepper disease worldwide. Recent outbreaks of bacterial spot disease in Central Brazil and…”
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13
Comparative NanoUPLC-MS E analysis between magainin I-susceptible and -resistant Escherichia coli strains
Published in Scientific reports (23-06-2017)“…In recent years the antimicrobial peptides (AMPs) have been prospected and designed as new alternatives to conventional antibiotics. Indeed, AMPs have…”
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14
Acknowledgement to Reviewers of Plants in 2019
Published in Plants (Basel) (17-01-2020)“…The editorial team greatly appreciates the reviewers who have dedicated their considerable time and expertise to the journal’s rigorous editorial process over…”
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Screening and isolation of antibacterial proteinaceous compounds from flower tissues: Alternatives for treatment of healthcare-associated infections
Published in Tang (2014)“…Healthcare-associated infection represents a frequent cause of mortality that increases hospital costs. Due to increasing microbial resistance to antibiotics,…”
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