Search Results - "C, Dimayuga"

The cathelicidin protein CRAMP is a potential atherosclerosis self-antigen in ApoE(-/-) mice by Mihailovic, Peter M, Lio, Wai Man, Yano, Juliana, Zhao, Xiaoning, Zhou, Jianchang, Chyu, Kuang-Yuh, Shah, Prediman K, Cercek, Bojan, Dimayuga, Paul C

“…Auto-immunity is believed to contribute to inflammation in atherosclerosis. The antimicrobial peptide LL-37, a fragment of the cathelicidin protein precursor…”
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Vaccine for Atherosclerosis by Shah, Prediman K., MD, Chyu, Kuang-Yuh, MD, PhD, Dimayuga, Paul C., PhD, Nilsson, Jan, MD, PhD

“…Abstract Atherosclerosis is an immune-mediated inflammatory disease of the arterial wall, with both the innate and adaptive immune systems responding to many…”
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Impaired tolerance to the autoantigen LL-37 in acute coronary syndrome by Chernomordik, Fernando, Cercek, Bojan, Zhou, Jianchang, Zhao, Xiaoning, Lio, Nicole Wai Man, Chyu, Kuang-Yuh, Shah, Prediman K, Dimayuga, Paul C

“…LL-37 is the only member of the cathelicidin family of antimicrobial peptides in humans and is an autoantigen in several autoimmune diseases and in acute…”
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CD8+ T cells mediate the athero-protective effect of immunization with an ApoB-100 peptide by Chyu, Kuang-Yuh, Zhao, Xiaoning, Dimayuga, Paul C, Zhou, Jianchang, Li, Xiaojun, Yano, Juliana, Lio, Wai Man, Chan, Lai Fan, Kirzner, Jonathan, Trinidad, Portia, Cercek, Bojan, Shah, Prediman K

“…Immunization of hypercholesterolemic mice with selected apoB-100 peptide antigens reduces atherosclerosis but the precise immune mediators of athero-protection…”
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Keratin 8 is a potential self-antigen in the coronary artery disease immunopeptidome: A translational approach by Mihailovic, Peter M, Lio, Wai Man, Herscovici, Romana, Chyu, Kuang-Yuh, Yano, Juliana, Zhao, Xiaoning, Zhou, Jianchang, Zhou, Bo, Freeman, Michael R, Yang, Wei, Shah, Prediman K, Cercek, Bojan, Dimayuga, Paul C

“…Inflammation is an important risk factor in atherosclerosis, the underlying cause of coronary artery disease (CAD). Unresolved inflammation may result in…”
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The Role of T Cells Reactive to the Cathelicidin Antimicrobial Peptide LL-37 in Acute Coronary Syndrome and Plaque Calcification by Chernomordik, Fernando, Cercek, Bojan, Lio, Wai Man, Mihailovic, Peter M, Yano, Juliana, Herscovici, Romana, Zhao, Xiaoning, Zhou, Jianchang, Chyu, Kuang-Yuh, Shah, Prediman K, Dimayuga, Paul C

“…The human cationic anti-microbial peptide LL-37 is a T cell self-antigen in patients with psoriasis, who have increased risk of cardiovascular events. However,…”
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Cholesterol lowering modulates T cell function in vivo and in vitro by Chyu, Kuang-Yuh, Lio, Wai Man, Dimayuga, Paul C, Zhou, Jianchang, Zhao, Xiaoning, Yano, Juliana, Trinidad, Portia, Honjo, Tomoyuki, Cercek, Bojan, Shah, Prediman K

“…The lipid milleu exacerbates the inflammatory response in atherosclerosis but its effect on T cell mediated immune response has not been fully elucidated. We…”
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ApoB-100–Related Peptide Vaccine Protects Against Angiotensin II–Induced Aortic Aneurysm Formation and Rupture by Honjo, Tomoyuki, MD, PhD, Chyu, Kuang-Yuh, MD, PhD, Dimayuga, Paul C., PhD, Yano, Juliana, BS, Lio, Wai Man, BS, Trinidad, Portia, BS, Zhao, Xiaoning, PhD, Zhou, Jianchang, MD, PhD, Chen, Shuang, PhD, Cercek, Bojan, MD, PhD, Arditi, Moshe, MD, Shah, Prediman K., MD

“…Abstract Background T cells and macrophages are implicated in the pathogenesis of aortic aneurysm (AA) and atherosclerosis. We recently demonstrated that a…”
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Immunization using ApoB-100 peptide-linked nanoparticles reduces atherosclerosis by Chyu, Kuang-Yuh, Zhao, Xiaoning, Zhou, Jianchang, Dimayuga, Paul C, Lio, Nicole Wm, Cercek, Bojan, Trac, Noah T, Chung, Eun Ji, Shah, Prediman K

“…Active immunization with the apolipoprotein B-100 (ApoB-100) peptide P210 reduces experimental atherosclerosis. To advance this immunization strategy to future…”
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Lessons Learned: Patient Communication During the Pandemic by EHM, Wang, I, Real, A, David-Wang, DA, Rubio, CL, Gaston, AJ, Quintos, C, Dimayuga, E, Dacanay

“…A series of mortalities among musculoskeletal tumour patients secondary to medical illnesses during the first few months of the pandemic highlighted the need…”
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Sex as a Determinant of Responses to a Coronary Artery Disease Self-Antigen Identified by Immune-Peptidomics by Lio, Wai Man, Cercek, Bojan, Yano, Juliana, Yang, Wei, Ghermezi, Jonathan, Zhao, Xiaoning, Zhou, Jianchang, Zhou, Bo, Freeman, Michael R, Chyu, Kuang-Yuh, Shah, Prediman K, Dimayuga, Paul C

“…A significant body of work implicates the adaptive immune response in atherosclerosis, the main underlying cause of coronary artery disease (CAD), yet specific…”
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Identification of apoB‐100 Peptide‐Specific CD8+ T Cells in Atherosclerosis by Dimayuga, Paul C., Zhao, Xiaoning, Yano, Juliana, Lio, Wai Man, Zhou, Jianchang, Mihailovic, Peter M., Cercek, Bojan, Shah, Prediman K., Chyu, Kuang‐Yuh

“…Background T cells are found in atherosclerotic plaques, with evidence supporting a potential role for CD8+ T cells in atherogenesis. Prior studies provide…”
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Immunization with an ApoB-100 Related Peptide Vaccine Attenuates Angiotensin-II Induced Hypertension and Renal Fibrosis in Mice by Honjo, Tomoyuki, Chyu, Kuang-Yuh, Dimayuga, Paul C, Lio, Wai Man, Yano, Juliana, Trinidad, Portia, Zhao, Xiaoning, Zhou, Jianchang, Cercek, Bojan, Shah, Prediman K

“…Recent studies suggest the potential involvement of CD8+ T cells in the pathogenesis of murine hypertension. We recently reported that immunization with…”
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Differential effects of apolipoprotein A-I-mimetic peptide on evolving and established atherosclerosis in apolipoprotein E-null mice by XIAOJUN LI, CHYU, Kuang-Yuh, FARIA, Jose R, YANO, Juliana, NATHWANI, Nitya, FERREIRA, Carmel, DIMAYUGA, Paul C, CERCEK, Bojan, KAUL, Sanjay, SHAH, Prediman K

“…Apolipoprotein (apo) A-I and apoA-I-mimetic peptides showed promise to prevent atherosclerosis development. Using a bypassed vein graft model in apoE-null…”
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Immune-modulation by polyclonal IgM treatment reduces atherosclerosis in hypercholesterolemic apoE−/− mice by Cesena, Fernando H.Y, Dimayuga, Paul C, Yano, Juliana, Zhao, Xiaoning, Kirzner, Jonathan, Zhou, Jianchang, Chan, Lai Fan, Lio, Wai Man, Cercek, Bojan, Shah, Prediman K, Chyu, Kuang-Yuh

“…Abstract Objective Gamma-globulin treatment reduces experimental atherosclerosis by modulating immune function; however the effect of IgM on atherosclerosis is…”
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IL-7R blockade reduces post-myocardial infarction-induced atherosclerotic plaque inflammation in ApoE -/- mice by Mihailovic, Peter M, Lio, Wai Man, Yano, Juliana, Zhou, Jianchang, Zhao, Xiaoning, Chyu, Kuang-Yuh, Shah, Prediman K, Cercek, Bojan, Dimayuga, Paul C

“…Modulating inflammation by targeting IL-1β reduces recurrent athero-thrombotic cardiovascular events without lipid lowering. This presents an opportunity to…”
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Enhanced neointima formation following arterial injury in immune deficient Rag-1-/- mice is attenuated by adoptive transfer of CD8 T cells by Dimayuga, Paul C, Chyu, Kuang-Yuh, Kirzner, Jonathan, Yano, Juliana, Zhao, Xiaoning, Zhou, Jianchang, Shah, Prediman K, Cercek, Bojan

“…T cells modulate neointima formation after arterial injury but the specific T cell population that is activated in response to arterial injury remains unknown…”
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Vaccine against arteriosclerosis: an update by Chyu, Kuang-Yuh, Dimayuga, Paul C., Shah, Prediman K.

“…Substantial data from experimental and clinical investigation support the role of immune-mediated mechanisms in atherogenesis, with immune systems responding…”
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T Cell Modulation of Intimal Thickening After Vascular Injury: The Bimodal Role of IFN-γ in Immune Deficiency by Dimayuga, Paul C, Li, Hongyan, Chyu, Kuang-Yuh, Fredrikson, Gunilla Nordin, Nilsson, Jan, Fishbein, Michael C, Shah, Prediman K, Cercek, Bojan

“…BACKGROUND—Immune deficiency results in exuberant intimal thickening after arterial injury. The mechanisms involved are not well defined. We investigated the…”
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Immunization using an Apo B-100 related epitope reduces atherosclerosis and plaque inflammation in hypercholesterolemic apo E (−/−) mice by Chyu, Kuang-Yuh, Zhao, Xiaoning, Reyes, Odette S., Babbidge, Stephanie M., Dimayuga, Paul C., Yano, Juliana, Cercek, Bojan, Fredrikson, Gunilla Nordin, Nilsson, Jan, Shah, Prediman K.

“…Immune system modulates atherosclerosis and immunization using homologous LDL reduces atherosclerosis in hyperlipidemic animals. The nature of…”
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