Search Results - "Byun, Sanguine"
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Therapeutic Implications of Autophagy Inducers in Immunological Disorders, Infection, and Cancer
Published in International journal of molecular sciences (12-09-2017)“…Autophagy is an essential catabolic program that forms part of the stress response and enables cells to break down their own intracellular components within…”
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Modulation of Autophagy for Controlling Immunity
Published in Cells (Basel, Switzerland) (09-02-2019)“…Autophagy is an essential process that maintains physiological homeostasis by promoting the transfer of cytoplasmic constituents to autophagolysosomes for…”
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3
Induction of Synthetic Lethality by Natural Compounds Targeting Cancer Signaling
Published in Current pharmaceutical design (16-11-2017)“…Despite the breakthroughs that have been achieved, significant unmet needs relating to the inadequate efficacy and toxicity of currently-available cancer…”
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4
Immunomodulatory functional foods and their molecular mechanisms
Published in Experimental & molecular medicine (01-01-2022)“…The immune system comprises a complex group of processes that provide defense against diverse pathogens. These defenses can be divided into innate and adaptive…”
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Quercetin Directly Targets JAK2 and PKCδ and Prevents UV-Induced Photoaging in Human Skin
Published in International journal of molecular sciences (23-10-2019)“…Quercetin is a naturally occurring polyphenol present in various fruits and vegetables. The bioactive properties of quercetin include anti-oxidative,…”
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6
Control of signaling-mediated clearance of apoptotic cells by the tumor suppressor p53
Published in Science (American Association for the Advancement of Science) (31-07-2015)“…The inefficient clearance of dying cells can lead to abnormal immune responses, such as unresolved inflammation and autoimmune conditions. We show that tumor…”
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Direct Targeting of β-Catenin by a Small Molecule Stimulates Proteasomal Degradation and Suppresses Oncogenic Wnt/β-Catenin Signaling
Published in Cell reports (Cambridge) (28-06-2016)“…The Wnt/β-catenin signaling pathway plays a major role in tissue homeostasis, and its dysregulation can lead to various human diseases. Aberrant activation of…”
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Caffeic Acid Phenethyl Ester Inhibits UV-Induced MMP-1 Expression by Targeting Histone Acetyltransferases in Human Skin
Published in International journal of molecular sciences (22-06-2019)“…Caffeic acid phenethyl ester (CAPE), a naturally occurring bioactive compound, displays anti-inflammatory, anti-carcinogenic, and anti-microbial effects…”
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USP8 Is a Novel Target for Overcoming Gefitinib Resistance in Lung Cancer
Published in Clinical cancer research (15-07-2013)“…Common treatment modalities for non-small cell lung cancer (NSCLC) involve the EGF receptor-tyrosine kinase inhibitors (EGFR-TKIs) like gefitinib and…”
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10
Piceatannol Enhances Cisplatin Sensitivity in Ovarian Cancer via Modulation of p53, X-linked Inhibitor of Apoptosis Protein (XIAP), and Mitochondrial Fission
Published in The Journal of biological chemistry (16-08-2013)“…Resistance to cisplatin (CDDP) in ovarian cancer (OVCA) arises from the dysregulation of tumor suppressors and survival signals. During genotoxic challenge,…”
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A Host-Restricted Self-Attenuated Influenza Virus Provides Broad Pan-Influenza A Protection in a Mouse Model
Published in Frontiers in immunology (02-12-2021)“…Influenza virus infections can cause a broad range of symptoms, form mild respiratory problems to severe and fatal complications. While influenza virus poses a…”
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Functional foods with antiviral activity
Published in Food science and biotechnology (01-05-2022)“…Viruses are known to cause a variety of diseases, ranging from mild respiratory diseases, such as the common cold, to fatal illnesses. Although the development…”
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13
Src kinase is a direct target of apigenin against UVB-induced skin inflammation
Published in Carcinogenesis (New York) (01-02-2013)“…Apigenin, a flavonoid abundant in various vegetables and fruits, including parsley and onions, has been reported to possess anticarcinogenic effects. However,…”
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14
Epigallocatechin-3-Gallate as a Novel Vaccine Adjuvant
Published in Frontiers in immunology (12-11-2021)“…Vaccine adjuvants from natural resources have been utilized for enhancing vaccine efficacy against infectious diseases. This study examined the potential use…”
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CDIP1-BAP31 Complex Transduces Apoptotic Signals from Endoplasmic Reticulum to Mitochondria under Endoplasmic Reticulum Stress
Published in Cell reports (Cambridge) (01-10-2013)“…Resolved endoplasmic reticulum (ER) stress response is essential for intracellular homeostatic balance, but unsettled ER stress can lead to apoptosis. Here, we…”
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Rice Bran Extract Suppresses High-Fat Diet-Induced Hyperlipidemia and Hepatosteatosis through Targeting AMPK and STAT3 Signaling
Published in Nutrients (01-08-2023)“…Rice bran, a by-product of rice milling, is abundant in bioactive molecules and is highly recognized for its health-promoting properties, particularly in…”
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Propolis Suppresses UV-Induced Photoaging in Human Skin through Directly Targeting Phosphoinositide 3-Kinase
Published in Nutrients (10-12-2020)“…Propolis is a resinous substance generated by bees using materials from various plant sources. It has been known to exhibit diverse bioactivities including…”
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Red Ginseng Improves Exercise Endurance by Promoting Mitochondrial Biogenesis and Myoblast Differentiation
Published in Molecules (Basel, Switzerland) (16-02-2020)“…Red ginseng has been reported to elicit various therapeutic effects relevant to cancer, diabetes, neurodegenerative diseases, and inflammatory diseases…”
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Molecular targets of exercise mimetics and their natural activators
Published in BMB reports (31-12-2021)“…Physical exercise can be effective in preventing or ameliorating various diseases, including diabetes, cardiovascular diseases, neurodegenerative diseases, and…”
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Myricetin suppresses UVB-induced skin cancer by targeting Fyn
Published in Cancer research (Chicago, Ill.) (15-07-2008)“…Skin cancer is currently the most common type of human cancer in Americans. Myricetin, a naturally occurring phytochemical, has potent anticancer-promoting…”
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