Search Results - "Bystry, Darlene M."
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Phase Ib study of HSP90 inhibitor, onalespib (AT13387), in combination with paclitaxel in patients with advanced triple-negative breast cancer
Published in Therapeutic advances in medical oncology (01-01-2023)“…Background: Heat shock protein 90 (HSP90) is a molecular chaperone required for stabilization of client proteins over-activated in triple-negative breast…”
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Journal Article -
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Early Intervention with Lenalidomide in Patients with High-risk Chronic Lymphocytic Leukemia
Published in Clinical cancer research (01-12-2020)“…Infectious complications constitute a leading cause of morbidity and mortality in chronic lymphocytic leukemia (CLL). Patients respond poorly to vaccines,…”
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Abstract 7632: Final survival outcomes and post-hoc tumor gene expression pathway analyses of complete responders from a phase Ib clinical trial of HSP90 inhibitor onalespib and paclitaxel in patients with advanced triple-negative breast cancer
Published in Cancer research (Chicago, Ill.) (22-03-2024)“…Abstract Background: Heat shock protein 90 (HSP90) is a molecular chaperone required for stabilization of client proteins over-activated in triple-negative…”
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Journal Article