Search Results - "Byström, Julia Wigren"
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Hybrid capture-based next-generation sequencing of new and old world Orthohantavirus strains and wild-type Puumala isolates from humans and bank voles
Published in Journal of clinical virology (01-06-2024)“…•Genomic characterization of viruses is essential to understand their pathophysiology.•We have designed a targeted hybrid-capture panel encompassing all…”
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Convalescence plasma treatment of COVID-19: results from a prematurely terminated randomized controlled open-label study in Southern Sweden
Published in BMC research notes (04-12-2021)“…Abstract Objective Convalescent plasma has been tried as therapy for various viral infections. Early observational studies of convalescent plasma treatment for…”
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Generation of plasma cells and CD27−IgD− B cells during hantavirus infection is associated with distinct pathological findings
Published in Clinical & translational immunology (2021)“…Objective Human hantavirus infections can cause haemorrhagic fever with renal syndrome (HFRS). The pathogenic mechanisms are not fully understood, nor if they…”
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SARS-CoV-2-related mortality decrease in nursing home residents given multiple COVID-19 boosters
Published in The Lancet infectious diseases (01-10-2023)“…Two doses of COVID-19 mRNA vaccines in the primary series and a booster dose induce a strong antibody response, however, this response can be weak in people…”
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Clinical and genomic characterisation of a fatal Puumala orthohantavirus case with low levels of neutralising antibodies
Published in Infectious diseases (London, England) (03-10-2022)“…Orthohantaviruses are rodent-borne emerging viruses that cause haemorrhagic fever with renal syndrome (HFRS) in Eurasia and hantavirus pulmonary syndrome in…”
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Human antibody recognizing a quaternary epitope in the Puumala virus glycoprotein provides broad protection against orthohantaviruses
Published in Science translational medicine (16-03-2022)“…The rodent-borne hantavirus Puumala virus (PUUV) and related agents cause hemorrhagic fever with renal syndrome (HFRS) in humans. Other hantaviruses, including…”
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Seroprevalence of SARS-CoV-2 in Sweden, April 26 to May 9, 2021
Published in Scientific reports (25-06-2022)“…A national point seroprevalence study of SARS-CoV-2 was conducted in Sweden in April–May 2021. In total, 2860 individuals 3 to 90 years old from a…”
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At-home sampling to meet geographical challenges for serological assessment of SARS-CoV-2 exposure in a rural region of northern Sweden, March to May 2021: a retrospective cohort study
Published in Euro surveillance : bulletin européen sur les maladies transmissibles (30-03-2023)“…BackgroundThe current SARS-CoV-2 pandemic has highlighted a need for easy and safe blood sampling in combination with accurate serological methodology…”
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Quantification and kinetics of viral RNA transcripts produced in Orthohantavirus infected cells
Published in Virology journal (19-01-2018)“…Rodent borne viruses of the Orthohantavirus genus cause hemorrhagic fever with renal syndrome among people in Eurasia, and hantavirus cardiopulmonary syndrome…”
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MAIT cell activation is associated with disease severity markers in acute hantavirus infection
Published in Cell reports. Medicine (16-03-2021)“…Hantaviruses are zoonotic RNA viruses that cause severe acute disease in humans. Infected individuals have strong inflammatory responses that likely cause…”
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Direct and indirect effects of Puumala hantavirus on platelet function
Published in Thrombosis research (01-01-2024)“…Thrombocytopenia is a cardinal symptom of hantavirus-induced diseases including Puumala virus (PUUV)-induced hemorrhagic fever with renal syndrome (HFRS),…”
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Evaluation of 11 SARS-CoV-2 antibody tests by using samples from patients with defined IgG antibody titers
Published in Scientific reports (07-04-2021)“…We evaluated the performance of 11 SARS-CoV-2 antibody tests using a reference set of heat-inactivated samples from 278 unexposed persons and 258 COVID-19…”
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Vaccine-induced correlate of protection against fatal COVID-19 in older and frail adults during waves of neutralization-resistant variants of concern: an observational study
Published in The Lancet regional health. Europe (06-05-2023)“…To inform future preventive measures including repeated vaccinations, we have searched for a clinically useful immune correlate of protection against fatal…”
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Clinical and genomic characterisation of a fatal Puumala orthohantavirus case with low levels of neutralising antibodies
Published in Infectious Diseases (03-10-2022)“…Orthohantaviruses are rodent-borne emerging viruses that cause haemorrhagic fever with renal syndrome (HFRS) in Eurasia and hantavirus pulmonary syndrome in…”
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