Search Results - "Byrne, Noel J"

Structures of active-state orexin receptor 2 rationalize peptide and small-molecule agonist recognition and receptor activation by Hong, Chuan, Byrne, Noel J., Zamlynny, Beata, Tummala, Srivanya, Xiao, Li, Shipman, Jennifer M., Partridge, Andrea T., Minnick, Christina, Breslin, Michael J., Rudd, Michael T., Stachel, Shawn J., Rada, Vanessa L., Kern, Jeffrey C., Armacost, Kira A., Hollingsworth, Scott A., O’Brien, Julie A., Hall, Dawn L., McDonald, Terrence P., Strickland, Corey, Brooun, Alexei, Soisson, Stephen M., Hollenstein, Kaspar

“…Narcolepsy type 1 (NT1) is a chronic neurological disorder that impairs the brain’s ability to control sleep-wake cycles. Current therapies are limited to the…”
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Structure of Human Prostasin, a Target for the Regulation of Hypertension by Rickert, Keith W., Kelley, Paul, Byrne, Noel J., Diehl, Ronald E., Hall, Dawn L., Montalvo, Allison M., Reid, John C., Shipman, Jennifer M., Thomas, Bradley W., Munshi, Sanjeev K., Darke, Paul L., Su, Hua-Poo

“…Prostasin (also called channel activating protease-1 (CAP1)) is an extracellular serine protease implicated in the modulation of fluid and electrolyte…”
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A streamlined, automated workflow to screen and triage large numbers of baculoviruses for protein expression by Kostas, James J., Partridge, Andrea T., Byrne, Noel J., Edwards, Richard W., Su, Hua-Poo, Gabelli, Sandra B., Brooun, Alexei, Shipman, Jennifer M.

“…The baculovirus expression system is a powerful and widely used method to generate large quantities of recombinant protein. However, challenges exist in…”
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Development of a robust crystallization platform for immune receptor TREM2 using a crystallization chaperone strategy by Byrne, Noel J., Lee, Amy C., Kostas, James, Reid, John C., Partridge, Andrea T., So, Sung-Sau, Cowan, Joseph E., Abeywickrema, Pravien, Huang, Hua, Zebisch, Matthias, Barker, John J., Soisson, Stephen M., Brooun, Alexei, Su, Hua-Poo

“…TREM2 has been identified by genomic analysis as a potential and novel target for the treatment of Alzheimer's disease. To enable structure-based screening of…”
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Structural Basis for Selective Small Molecule Kinase Inhibition of Activated c-Met by Rickert, Keith W., Patel, Sangita B., Allison, Timothy J., Byrne, Noel J., Darke, Paul L., Ford, Rachael E., Guerin, David J., Hall, Dawn L., Kornienko, Maria, Lu, Jun, Munshi, Sanjeev K., Reid, John C., Shipman, Jennifer M., Stanton, Elizabeth F., Wilson, Kevin J., Young, Jonathon R., Soisson, Stephen M., Lumb, Kevin J.

“…The receptor tyrosine kinase c-Met is implicated in oncogenesis and is the target for several small molecule and biologic agents in clinical trials for the…”
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Structural definition and substrate specificity of the S28 protease family: the crystal structure of human prolylcarboxypeptidase by Soisson, Stephen M, Patel, Sangita B, Abeywickrema, Pravien D, Byrne, Noel J, Diehl, Ronald E, Hall, Dawn L, Ford, Rachael E, Reid, John C, Rickert, Keith W, Shipman, Jennifer M, Sharma, Sujata, Lumb, Kevin J

“…The unique S28 family of proteases is comprised of the carboxypeptidase PRCP and the aminopeptidase DPP7. The structural basis of the different substrate…”
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Expression, purification and crystallization of human prolylcarboxypeptidase by Abeywickrema, Pravien D., Patel, Sangita B., Byrne, Noel J., Diehl, Ronald E., Hall, Dawn L., Ford, Rachael E., Rickert, Keith W., Reid, John C., Shipman, Jennifer M., Geissler, Wayne M., Pryor, Kelly D., SinhaRoy, Ranabir, Soisson, Stephen M., Lumb, Kevin J., Sharma, Sujata

“…Prolylcarboxypeptidase (PrCP) is a lysosomal serine carboxypeptidase that cleaves a variety of C‐terminal amino acids adjacent to proline and has been…”
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Plants, animals, and industrial patents by Noel J BYRNE

“…This article considers how to effectively protect the potentially valuable results that emerge from costly enterprises to create or breed new or improved…”
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Structure of Human Prostasin, a Target for the Regulation of HypertensionS by Rickert, Keith W., Kelley, Paul, Byrne, Noel J., Diehl, Ronald E., Hall, Dawn L., Montalvo, Allison M., Reid, John C., Shipman, Jennifer M., Thomas, Bradley W., Munshi, Sanjeev K., Darke, Paul L., Su, Hua-Poo

“…Prostasin (also called channel activating protease-1 (CAP1)) is an extracellular serine protease implicated in the modulation of fluid and electrolyte…”
Get full text