Search Results - "Byrne, Jonathan J."

Regional adaptation defines sensitivity to future ocean acidification by Calosi, Piero, Melatunan, Sedercor, Turner, Lucy M., Artioli, Yuri, Davidson, Robert L., Byrne, Jonathan J., Viant, Mark R., Widdicombe, Stephen, Rundle, Simon D.

“…Physiological responses to temperature are known to be a major determinant of species distributions and can dictate the sensitivity of populations to global…”
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Modeling the metabolic profile of Mytilus edulis reveals molecular signatures linked to gonadal development, sex and environmental site by Kronberg, Jaanika, Byrne, Jonathan J., Jansen, Jeroen, Antczak, Philipp, Hines, Adam, Bignell, John, Katsiadaki, Ioanna, Viant, Mark R., Falciani, Francesco

“…The monitoring of anthropogenic chemicals in the aquatic environment including their potential effects on aquatic organisms, is important for protecting life…”
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Biomarkers of whale shark health: a metabolomic approach by Dove, Alistair D M, Leisen, Johannes, Zhou, Manshui, Byrne, Jonathan J, Lim-Hing, Krista, Webb, Harry D, Gelbaum, Leslie, Viant, Mark R, Kubanek, Julia, Fernández, Facundo M

“…In a search for biomarkers of health in whale sharks and as exploration of metabolomics as a modern tool for understanding animal physiology, the metabolite…”
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The Impact of Inflammation on Metabolomic Profiles in Patients With Arthritis by Young, Stephen P., Kapoor, Sabrina R., Viant, Mark R., Byrne, Jonathan J., Filer, Andrew, Buckley, Christopher D., Kitas, George D., Raza, Karim

“…Objective Inflammatory arthritis is associated with systemic manifestations including alterations in metabolism. We used nuclear magnetic resonance (NMR)…”
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(1)H NMR metabolomics reveals contrasting response by male and female mussels exposed to reduced seawater pH, increased temperature, and a pathogen by Ellis, Robert P, Spicer, John I, Byrne, Jonathan J, Sommer, Ulf, Viant, Mark R, White, Daniel A, Widdicombe, Steve

“…Human activities are fundamentally altering the chemistry of the world's oceans. Ocean acidification (OA) is occurring against a background of warming and an…”
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Fumarate Is Cardioprotective via Activation of the Nrf2 Antioxidant Pathway by Ashrafian, Houman, Czibik, Gabor, Bellahcene, Mohamed, Aksentijević, Dunja, Smith, Anthony C., Mitchell, Sarah J., Dodd, Michael S., Kirwan, Jennifer, Byrne, Jonathan J., Ludwig, Christian, Isackson, Henrik, Yavari, Arash, Støttrup, Nicolaj B., Contractor, Hussain, Cahill, Thomas J., Sahgal, Natasha, Ball, Daniel R., Birkler, Rune I.D., Hargreaves, Iain, Tennant, Daniel A., Land, John, Lygate, Craig A., Johannsen, Mogens, Kharbanda, Rajesh K., Neubauer, Stefan, Redwood, Charles, de Cabo, Rafael, Ahmet, Ismayil, Talan, Mark, Günther, Ulrich L., Robinson, Alan J., Viant, Mark R., Pollard, Patrick J., Tyler, Damian J., Watkins, Hugh

“…The citric acid cycle (CAC) metabolite fumarate has been proposed to be cardioprotective; however, its mechanisms of action remain to be determined. To augment…”
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1H chemical shifts in NMR. Part 27: proton chemical shifts in sulfoxides and sulfones and the magnetic anisotropy, electric field and steric effects of the SO bond by Abraham, Raymond J., Byrne, Jonathan J., Griffiths, Lee

“…The 1H chemical shifts of a series of sulfoxide and sulfone compounds in CDCl3 solvent were obtained from experiment and the literature. These included dialkyl…”
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1H chemical shifts in NMR: Part 23, the effect of dimethyl sulphoxide versus chloroform solvent on 1H chemical shifts by Abraham, Raymond J., Byrne, Jonathan J., Griffiths, Lee, Perez, Manuel

“…The 1H chemical shifts of 124 compounds containing a variety of functional groups have been recorded in CDCl3 and DMSO‐d6 (henceforth DMSO) solvents. The 1H…”
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1H NMR Metabolomics Reveals Contrasting Response by Male and Female Mussels Exposed to Reduced Seawater pH, Increased Temperature, and a Pathogen by Ellis, Robert P, Spicer, John I, Byrne, Jonathan J, Sommer, Ulf, Viant, Mark R, White, Daniel A, Widdicombe, Steve

“…Human activities are fundamentally altering the chemistry of the world’s oceans. Ocean acidification (OA) is occurring against a background of warming and an…”
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Conformational analysis: Part 42. A modelling and LIS/NMR investigation of the conformations of some aromatic SO compounds by Abraham, Raymond J., Byrne, Jonathan J., Griffiths, Lee, Sancassan, Fernando

“…A refined Lanthanide‐Induced‐Shift Analysis (LISA), in which both the paramagnetic and the diamagnetic lanthanide induced chemical shifts are normalised…”
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Birmingham Metabolite Library: a publicly accessible database of 1-D 1H and 2-D 1H J-resolved NMR spectra of authentic metabolite standards (BML-NMR) by Ludwig, Christian, Easton, John M., Lodi, Alessia, Tiziani, Stefano, Manzoor, Susan E., Southam, Andrew D., Byrne, Jonathan J., Bishop, Lisa M., He, Shan, Arvanitis, Theodoros N., Günther, Ulrich L., Viant, Mark R.

“…Public databases of NMR spectra of low molecular weight metabolites must be constructed to remove the major bottleneck of metabolite identification and…”
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1H chemical shifts in NMR: Part 22-Prediction of the 1H chemical shifts of alcohols, diols and inositols in solution, a conformational and solvation investigation by Abraham, Raymond J., Byrne, Jonathan J., Griffiths, Lee, Koniotou, Rodothea

“…The 1H NMR spectra of a number of alcohols, diols and inositols are reported and assigned in CDCl3, D2O and DMSO‐d6 (henceforth DMSO) solutions. These data…”
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1H chemical shifts in NMR: Part 22—Prediction of the1H chemical shifts of alcohols, diols and inositols in solution, a conformational and solvation investigation by Abraham, Raymond J., Byrne, Jonathan J., Griffiths, Lee, Koniotou, Rodothea

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Approaches and Considerations for the Investigation and Synthesis of N‑Nitrosamine Drug Substance-Related Impurities (NDSRIs) by Ashworth, Ian W., Blanazs, Alexander, Byrne, Jonathan J., Dirat, Olivier, Fennell, Jared W., Kuhl, Nadine, Wells, Stuart L., Whiting, Matthew P.

“…N-Nitrosamine risk assessment of pharmaceuticals has moved from an initial focus on the potential presence of known small-molecule N-nitrosamines such as…”
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sup 1^H NMR Metabolomics Reveals Contrasting Response by Male and Female Mussels Exposed to Reduced Seawater pH, Increased Temperature, and a Pathogen by Ellis, Robert P, Spicer, John I, Byrne, Jonathan J, Sommer, Ulf, Viant, Mark R, White, Daniel A, Widdicombe, Steve

“…Human activities are fundamentally altering the chemistry of the world's oceans. Ocean acidification (OA) is occurring against a background of warming and an…”
Get full text

1 H NMR Metabolomics Reveals Contrasting Response by Male and Female Mussels Exposed to Reduced Seawater pH, Increased Temperature, and a Pathogen by Ellis, Robert P., Spicer, John I., Byrne, Jonathan J., Sommer, Ulf, Viant, Mark R., White, Daniel A., Widdicombe, Steve

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1 H chemical shifts in NMR. Part 27: proton chemical shifts in sulfoxides and sulfones and the magnetic anisotropy, electric field and steric effects of the SO bond by Abraham, Raymond J., Byrne, Jonathan J., Griffiths, Lee

“…Abstract The 1 H chemical shifts of a series of sulfoxide and sulfone compounds in CDCl 3 solvent were obtained from experiment and the literature. These…”
Get full text

Birmingham Metabolite Library: a publicly accessible database of 1-D super(1)H and 2-D super(1)H J-resolved NMR spectra of authentic metabolite standards (BML-NMR) by Ludwig, Christian, Easton, John M, Lodi, Alessia, Tiziani, Stefano, Manzoor, Susan E, Southam, Andrew D, Byrne, Jonathan J, Bishop, Lisa M, He, Shan, Arvanitis, Theodoros N, Guenther, Ulrich L, Viant, Mark R

“…Public databases of NMR spectra of low molecular weight metabolites must be constructed to remove the major bottleneck of metabolite identification and…”
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Birmingham Metabolite Library: a publicly accessible database of 1-D ^sup 1^H and 2-D ^sup 1^H J-resolved NMR spectra of authentic metabolite standards (BML-NMR) by Ludwig, Christian, Easton, John M, Lodi, Alessia, Tiziani, Stefano, Manzoor, Susan E, Southam, Andrew D, Byrne, Jonathan J, Bishop, Lisa M, He, Shan, Arvanitis, Theodoros N, Günther, Ulrich L, Viant, Mark R

“…Public databases of NMR spectra of low molecular weight metabolites must be constructed to remove the major bottleneck of metabolite identification and…”
Get full text

1 H chemical shifts in NMR: Part 23, the effect of dimethyl sulphoxide versus chloroform solvent on 1 H chemical shifts by Abraham, Raymond J., Byrne, Jonathan J., Griffiths, Lee, Perez, Manuel

“…Abstract The 1 H chemical shifts of 124 compounds containing a variety of functional groups have been recorded in CDCl 3 and DMSO‐ d 6 (henceforth DMSO)…”
Get full text