Search Results - "Byrn, Randal R"

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    Isosteric replacements of the carboxylic acid of drug candidate VX-787: Effect of charge on antiviral potency and kinase activity of azaindole-based influenza PB2 inhibitors

    Isosteric replacements of the carboxylic acid of drug candidate VX-787: Effect of charge on antiviral potency and kinase activity of azaindole-based influenza PB2 inhibitors by Boyd, Michael J, Bandarage, Upul K, Bennett, Hamilton, Byrn, Randal R, Davies, Ioana, Gu, Wenxin, Jacobs, Marc, Ledeboer, Mark W, Ledford, Brian, Leeman, Joshua R, Perola, Emanuele, Wang, Tiansheng, Bennani, Youssef, Clark, Michael P, Charifson, Paul S

    Published in Bioorganic & medicinal chemistry letters (01-05-2015)
    “…VX-787 is a first in class, orally bioavailable compound that offers unparalleled potential for the treatment of pandemic and seasonal influenza. As a part of…”
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    Corrigendum to “Isosteric replacements of the carboxylic acid of drug candidate VX-787: Effect of charge on antiviral potency and kinase activity of azaindole-based influenza PB2 inhibitors” [Bioorg. Med. Chem. Lett. 25 (2015) 1990–1994]

    Corrigendum to “Isosteric replacements of the carboxylic acid of drug candidate VX-787: Effect of charge on antiviral potency and kinase activity of azaindole-based influenza PB2 inhibitors” [Bioorg. Med. Chem. Lett. 25 (2015) 1990–1994] by Boyd, Michael J., Bandarage, Upul K., Bennett, Hamilton, Byrn, Randal R., Davies, Ioana, Gu, Wenxin, Jacobs, Marc, Ledeboer, Mark W., Ledford, Brian, Leeman, Joshua R., Perola, Emanuele, Wang, Tiansheng, Bennani, Youssef, Clark, Michael P., Charifson, Paul S.

    Published in Bioorganic & medicinal chemistry letters (01-01-2016)
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