Search Results - "Byrd, Matthew R."

Synthesis and immunostimulatory activity of substituted TLR7 agonists by Akinbobuyi, Babatope, Wang, Lei, Upchurch, Katherine C., Byrd, Matthew R., Chang, Charles A., Quintana, Jeremy M., Petersen, Rachel E., Seifert, Zacharie J., Boquin, José R., Oh, SangKon, Kane, Robert R.

“…[Display omitted] Fifteen new substituted adenines were synthesized as potential TLR7 agonists. These compounds, along with 9 previously reported compounds,…”
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Facile syntheses of functionalized toll-like receptor 7 agonists by Akinbobuyi, Babatope, Byrd, Matthew R., Chang, Charles A., Nguyen, Mysa, Seifert, Zacharie J., Flamar, Anne-Laure, Zurawski, Gerard, Upchurch, Katherine C., Oh, SangKon, Dempsey, Stephen H., Enke, Thomas J., Le, John, Winstead, Hunter J., Boquín, José R., Kane, Robert R.

“…9 new TLR-7 agonists; 10–70% overall for 4–7 steps. X=H, I, CO2H, CN, CONH2, CCCH2OH, CCCH2NH2, (CH2)3NH2, CONHCH2CH2NH2, CONH-PEG2-NH2. [Display omitted]…”
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