Search Results - "Byers, Jessie Nedrow"
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A phosphoramidate-based prostate-specific membrane antigen-targeted SPECT agent
Published in The Prostate (01-06-2012)“…BACKGROUND Prostate‐specific membrane antigen (PSMA) remains an active target for imaging and therapeutic applications for prostate cancer. METHODS In the…”
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PSMA-targeted SPECT agents: Mode of binding effect on in vitro performance
Published in The Prostate (01-03-2013)“…BACKGROUND The enzyme‐biomarker prostate‐specific membrane antigen (PSMA) is an active target for imaging and therapeutic applications for prostate cancer. The…”
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Spacer length effects on in vitro imaging and surface accessibility of fluorescent inhibitors of prostate specific membrane antigen
Published in Bioorganic & medicinal chemistry letters (01-12-2011)“…A series of spacer-varied imaging probes were synthesized and evaluated, which exhibited spacer length-dependent effects on inhibitory potency, mode of…”
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Targeting prostate cancer cells with PSMA inhibitor-guided gold nanoparticles
Published in Bioorganic & medicinal chemistry letters (15-01-2013)“…Prostate-specific membrane antigen (PSMA) is a notable biomarker for diagnostic and therapeutic applications in prostate cancer. Gold nanoparticles (AuNPs)…”
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Detection of prostate-specific membrane antigen on HUVECs in response to breast tumor-conditioned medium
Published in International journal of oncology (01-05-2011)“…Prostate-specific membrane antigen (PSMA), a well-known biomarker of prostate cancer, has also been found to be highly expressed in the neovasculature of…”
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Targeting prostate cancer cells with a multivalent PSMA inhibitor-guided streptavidin conjugate
Published in Bioorganic & medicinal chemistry letters (15-06-2012)“…A series of spacer-varied biotinylated PSMA inhibitors were synthesized and evaluated, which exhibited spacer length-dependent effects on inhibitory potency,…”
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Assessment of an 18F-Labeled Phosphoramidate Peptidomimetic as a New Prostate-Specific Membrane Antigen-Targeted Imaging Agent for Prostate Cancer
Published in The Journal of nuclear medicine (1978) (01-12-2009)“…Prostate-specific membrane antigen (PSMA) is a transmembrane protein commonly found on the surface of late-stage and metastatic prostate cancer and a…”
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Abstract A117: Rapid uptake of a streptavidin conjugate into prostate cancer cells: A model of macromolecule targeting delivery
Published in Molecular cancer therapeutics (12-11-2011)“…Abstract Introduction: Prostate-specific membrane antigen (PSMA), a type II membrane glycoprotein, has been confirmed to be an important tumor-marker…”
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Assessment of an ^sup 18^F-Labeled Phosphoramidate Peptidomimetic as a New Prostate-Specific Membrane Antigen-Targeted Imaging Agent for Prostate Cancer
Published in The Journal of nuclear medicine (1978) (01-12-2009)“…Prostate-specific membrane antigen (PSMA) is a transmembrane protein commonly found on the surface of late-stage and metastatic prostate cancer and a…”
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The Question-Driven Laboratory Exercise: A New Pedagogy Applied to a Green Modification of Grignard Reagent Formation and Reaction
Published in Journal of chemical education (01-07-2010)“…Experimental exercises within second-year-level organic laboratory manuals typically involve a statement of a principle that is then validated by student…”
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Journal Article -
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Development of PSMA-targeted spect imaging agents for prostate cancer
Published 01-01-2012“…The cell-surface enzyme prostate-specific membrane antigen (PSMA) is up-regulated and strongly expressed on prostate cancer cells associated with high grade…”
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Dissertation