Search Results - "Byers, A"

Aperture-Opening Encapsulation of a Transition Metal Catalyst in a Metal–Organic Framework for CO2 Hydrogenation by Li, Zhehui, Rayder, Thomas M, Luo, Lianshun, Byers, Jeffery A, Tsung, Chia-Kuang

“…The aperture-opening process resulting from dissociative linker exchange in zirconium-based metal–organic framework (MOF) UiO-66 was used to encapsulate the…”
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Comparative study of lung and extrapulmonary poorly differentiated neuroendocrine carcinomas: A SEER database analysis of 162,983 cases by Dasari, Arvind, Mehta, Kathan, Byers, Lauren A., Sorbye, Halfdan, Yao, James C.

“…BACKGROUND Extrapulmonary neuroendocrine carcinomas (NECs) are poorly studied and are managed similar to lung NECs, which may not account for differences…”
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PARP Inhibitors: Extending Benefit Beyond BRCA -Mutant Cancers by Pilié, Patrick G, Gay, Carl M, Byers, Lauren A, O'Connor, Mark J, Yap, Timothy A

“…A mounting body of evidence now indicates that PARP inhibitors have the potential to be used as a foundation for both monotherapy and combination strategies…”
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Drought and climate change impacts on cooling water shortages and electricity prices in Great Britain by Byers, Edward A., Coxon, Gemma, Freer, Jim, Hall, Jim W.

“…The risks of cooling water shortages to thermo-electric power plants are increasingly studied as an important climate risk to the energy sector. Whilst…”
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Redox-Controlled Polymerization of Lactide Catalyzed by Bis(imino)pyridine Iron Bis(alkoxide) Complexes by Biernesser, Ashley B, Li, Bo, Byers, Jeffery A

“…Bis(imino)pyridine iron bis(alkoxide) complexes have been synthesized and utilized in the polymerization of (rac)-lactide. The activities of the catalysts were…”
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Smoking, p53 mutation, and lung cancer by Gibbons, Don L, Byers, Lauren A, Kurie, Jonathan M

“…This issue marks the 50th anniversary of the release of the U.S. Surgeon General's Report on Smoking and Health. Perhaps no other singular event has done more…”
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Engineering Second Sphere Interactions in a Host–Guest Multicomponent Catalyst System for the Hydrogenation of Carbon Dioxide to Methanol by Rayder, Thomas M, Bensalah, Adam T, Li, Banruo, Byers, Jeffery A, Tsung, Chia-Kuang

“…Many enzymes utilize interactions extending beyond the primary coordination sphere to enhance catalyst activity and/or selectivity. Such interactions could…”
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Collagen promotes anti-PD-1/PD-L1 resistance in cancer through LAIR1-dependent CD8+ T cell exhaustion by Peng, David H., Rodriguez, Bertha Leticia, Diao, Lixia, Chen, Limo, Wang, Jing, Byers, Lauren A., Wei, Ying, Chapman, Harold A., Yamauchi, Mitsuo, Behrens, Carmen, Raso, Gabriela, Soto, Luisa Maren Solis, Cuentes, Edwin Roger Parra, Wistuba, Ignacio I., Kurie, Jonathan M., Gibbons, Don L.

“…Tumor extracellular matrix has been associated with drug resistance and immune suppression. Here, proteomic and RNA profiling reveal increased collagen levels…”
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The role of Schlafen 11 (SLFN11) as a predictive biomarker for targeting the DNA damage response by Coleman, Niamh, Zhang, Bingnan, Byers, Lauren A., Yap, Timothy A.

“…Summary The therapeutic landscape of drugs targeting the DNA damage response (DDR) is rapidly expanding; however, an urgent unmet need remains for validated…”
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Electricity generation and cooling water use: UK pathways to 2050 by Byers, Edward A., Hall, Jim W., Amezaga, Jaime M.

“…•We present a validated model of water use from UK thermoelectric generation.•We calculate cooling water abstraction and consumption for pathways to…”
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City sicker? A meta-analysis of wildlife health and urbanization by Murray, Maureen H, Sánchez, Cecilia A, Becker, Daniel J, Byers, Kaylee A, Worsley-Tonks, Katherine EL, Craft, Meggan E

“…Urban development can alter resource availability, land use, and community composition, which, in turn, influences wildlife health. Generalizable relationships…”
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Block Copolymerization of Lactide and an Epoxide Facilitated by a Redox Switchable Iron-Based Catalyst by Biernesser, Ashley B., Delle Chiaie, Kayla R., Curley, Julia B., Byers, Jeffery A.

“…A cationic iron(III) complex was active for the polymerization of various epoxides, whereas the analogous neutral iron(II) complex was inactive. Cyclohexene…”
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The miR-200 family and the miR-183~96~182 cluster target Foxf2 to inhibit invasion and metastasis in lung cancers by Kundu, S T, Byers, L A, Peng, D H, Roybal, J D, Diao, L, Wang, J, Tong, P, Creighton, C J, Gibbons, D L

“…Metastatic lung cancer is one of the most lethal forms of cancer and molecular pathways driving metastasis are still not clearly elucidated. Metastatic cancer…”
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Rational Design of an Iron‐Based Catalyst for Suzuki–Miyaura Cross‐Couplings Involving Heteroaromatic Boronic Esters and Tertiary Alkyl Electrophiles by Crockett, Michael P., Wong, Alexander S., Li, Bo, Byers, Jeffery A.

“…Suzuki–Miyaura cross‐coupling reactions between a variety of alkyl halides and unactivated aryl boronic esters using a rationally designed iron‐based catalyst…”
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Metabolic Diversity in Human Non-Small Cell Lung Cancer Cells by Chen, Pei-Hsuan, Cai, Ling, Huffman, Kenneth, Yang, Chendong, Kim, Jiyeon, Faubert, Brandon, Boroughs, Lindsey, Ko, Bookyung, Sudderth, Jessica, McMillan, Elizabeth A., Girard, Luc, Chen, Dong, Peyton, Michael, Shields, Misty D., Yao, Bo, Shames, David S., Kim, Hyun Seok, Timmons, Brenda, Sekine, Ikuo, Britt, Rebecca, Weber, Stephanie, Byers, Lauren A., Heymach, John V., Chen, Jing, White, Michael A., Minna, John D., Xiao, Guanghua, DeBerardinis, Ralph J.

“…Intermediary metabolism in cancer cells is regulated by diverse cell-autonomous processes, including signal transduction and gene expression patterns, arising…”
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Multimorbidity patterns and health care utilization among older adults with schizophrenia by Hwong, A., Li, Y., Morin, R., Byers, A.

“…Introduction Older adults with schizophrenia often have multiple chronic conditions, or multimorbidity, yet most prior research has focused on single medical…”
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Proteomic Markers of DNA Repair and PI3K Pathway Activation Predict Response to the PARP Inhibitor BMN 673 in Small Cell Lung Cancer by CARDNELL, Robert J, YING FENG, BYERS, Lauren A, LIXIA DIAO, FAN, You-Hong, MASRORPOUR, Fatemah, JING WANG, YUQIAO SHEN, MILLS, Gordon B, MINNA, John D, HEYMACH, John V

“…Small cell lung carcinoma (SCLC) is an aggressive malignancy affecting nearly 30,000 people annually in the United States. We have previously identified…”
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CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells by Kim, Jiyeon, Hu, Zeping, Cai, Ling, Li, Kailong, Choi, Eunhee, Faubert, Brandon, Bezwada, Divya, Rodriguez-Canales, Jaime, Villalobos, Pamela, Lin, Yu-Fen, Ni, Min, Huffman, Kenneth E., Girard, Luc, Byers, Lauren A., Unsal-Kacmaz, Keziban, Peña, Christopher G., Heymach, John V., Wauters, Els, Vansteenkiste, Johan, Castrillon, Diego H., Chen, Benjamin P. C., Wistuba, Ignacio, Lambrechts, Diether, Xu, Jian, Minna, John D., DeBerardinis, Ralph J.

“…In human cell lines with mutant KRAS and loss of LKB1, CPS1 expression correlates inversely with LKB1 expression; silencing CPS1 in these cells induces DNA…”
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Comparative genomics of high grade neuroendocrine carcinoma of the cervix by Hillman, R Tyler, Cardnell, Robert, Fujimoto, Junya, Lee, Won-Chul, Zhang, Jianjun, Byers, Lauren A, Ramalingam, Preetha, Leitao, Mario, Swisher, Elizabeth, Futreal, P Andrew, Frumovitz, Michael

“…In order to improve treatment selection for high grade neuroendocrine carcinomas of the cervix (NECC), we performed a comparative genomic analysis between this…”
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Rovalpituzumab tesirine, a DLL3-targeted antibody-drug conjugate, in recurrent small-cell lung cancer: a first-in-human, first-in-class, open-label, phase 1 study by Rudin, Charles M, Prof, Pietanza, M Catherine, MD, Bauer, Todd M, MD, Ready, Neal, Prof, Morgensztern, Daniel, MD, Glisson, Bonnie S, Prof, Byers, Lauren A, MD, Johnson, Melissa L, MD, Burris, Howard A, MD, Robert, Francisco, Prof, Han, Tae H, PhD, Bheddah, Sheila, BA, Theiss, Noah, MS, Watson, Sky, BS, Mathur, Deepan, MD, Vennapusa, Bharathi, MD, Zayed, Hany, PhD, Lally, Satwant, MS, Strickland, Donald K, MD, Govindan, Ramaswamy, Prof, Dylla, Scott J, PhD, Peng, Stanford L, MD, Spigel, David R, MD

“…Summary Background Rovalpituzumab tesirine is a first-in-class antibody-drug conjugate directed against delta-like protein 3 (DLL3), a novel target identified…”
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