Search Results - "Bye, Chris R"

HIV-1 infection of human macrophages directly induces viperin which inhibits viral production by Nasr, Najla, Maddocks, Susan, Turville, Stuart G., Harman, Andrew N., Woolger, Natalie, Helbig, Karla J., Wilkinson, John, Bye, Chris R., Wright, Thomas K., Rambukwelle, Dharshini, Donaghy, Heather, Beard, Michael R., Cunningham, Anthony L.

“…Macrophages are key target cells for HIV-1. HIV-1BaL induced a subset of interferon-stimulated genes in monocyte-derived macrophages (MDMs), which differed…”
Get full text

Transcriptome analysis reveals transmembrane targets on transplantable midbrain dopamine progenitors by Bye, Chris R., Jönsson, Marie E., Björklund, Anders, Parish, Clare L., Thompson, Lachlan H.

“…Significance An important challenge for improving cell-based approaches for Parkinson’s disease is the development of techniques that facilitate greater…”
Get full text

Identification of lineage relationships and novel markers of blood and skin human dendritic cells by Harman, Andrew N, Bye, Chris R, Nasr, Najla, Sandgren, Kerrie J, Kim, Min, Mercier, Sarah K, Botting, Rachel A, Lewin, Sharon R, Cunningham, Anthony L, Cameron, Paul U

“…The lineage relationships and fate of human dendritic cells (DCs) have significance for a number of diseases including HIV where both blood and tissue DCs may…”
Get full text

Functional characterisation of the amyotrophic lateral sclerosis risk locus GPX3/TNIP1 by Restuadi, Restuadi, Steyn, Frederik J, Kabashi, Edor, Ngo, Shyuan T, Cheng, Fei-Fei, Nabais, Marta F, Thompson, Mike J, Qi, Ting, Wu, Yang, Henders, Anjali K, Wallace, Leanne, Bye, Chris R, Turner, Bradley J, Ziser, Laura, Mathers, Susan, McCombe, Pamela A, Needham, Merrilee, Schultz, David, Kiernan, Matthew C, van Rheenen, Wouter, van den Berg, Leonard H, Veldink, Jan H, Ophoff, Roel, Gusev, Alexander, Zaitlen, Noah, McRae, Allan F, Henderson, Robert D, Wray, Naomi R, Giacomotto, Jean, Garton, Fleur C

“…Amyotrophic lateral sclerosis (ALS) is a complex, late-onset, neurodegenerative disease with a genetic contribution to disease liability. Genome-wide…”
Get full text

Neuronal activity regulates expression of tyrosine hydroxylase in adult mouse substantia nigra pars compacta neurons by Aumann, Tim D., Egan, Kate, Lim, Jamie, Boon, Wah C., Bye, Chris R., Chua, Hui K., Baban, Natalija, Parish, Clare L., Bobrovskaya, Larisa, Dickson, Phillip, Horne, Malcolm K.

“…J. Neurochem. (2011) 116, 646–658. Striatal delivery of dopamine (DA) by midbrain substantia nigra pars compacta (SNc) neurons is vital for motor control and…”
Get full text

Dopamine D2 receptor knockout mice develop features of Parkinson disease by Tinsley, Rogan B., Bye, Chris R., Parish, Clare L., Tziotis-Vais, Angela, George, Sonia, Culvenor, Janetta G., Li, Qiao-Xin, Masters, Colin L., Finkelstein, David I., Horne, Malcolm K.

“…Objective This study questions whether increased dopamine (DA) turnover in nigral neurons leads to formation of Lewy bodies (LBs), the characteristic…”
Get full text

HIV Induces Maturation of Monocyte-Derived Dendritic Cells and Langerhans Cells by Harman, Andrew N, Wilkinson, John, Bye, Chris R, Bosnjak, Lidija, Stern, J. Lewis, Nicholle, Monique, Lai, Joey, Cunningham, Anthony L

“…In HIV infection, dendritic cells (DCs) may play multiple roles, probably including initial HIV uptake in the anogenital mucosa, transport to lymph nodes, and…”
Get full text

Protein disulphide isomerase protects against protein aggregation and is S-nitrosylated in amyotrophic lateral sclerosis by Walker, Adam K., Farg, Manal A., Bye, Chris R., McLean, Catriona A., Horne, Malcolm K., Atkin, Julie D.

“…Amyotrophic lateral sclerosis is a rapidly progressing fatal neurodegenerative disease characterized by the presence of protein inclusions within affected…”
Get full text

Efficiently Specified Ventral Midbrain Dopamine Neurons from Human Pluripotent Stem Cells Under Xeno‐Free Conditions Restore Motor Deficits in Parkinsonian Rodents by Niclis, Jonathan C., Gantner, Carlos W., Alsanie, Walaa F., McDougall, Stuart J., Bye, Chris R., Elefanty, Andrew G., Stanley, Edouard G., Haynes, John M., Pouton, Colin W., Thompson, Lachlan H., Parish, Clare L.

“…Recent studies have shown evidence for the functional integration of human pluripotent stem cell (hPSC)‐derived ventral midbrain dopamine (vmDA) neurons in…”
Get full text

HIV-1–infected dendritic cells show 2 phases of gene expression changes, with lysosomal enzyme activity decreased during the second phase by Harman, Andrew N., Kraus, Marianne, Bye, Chris R., Byth, Karen, Turville, Stuart G., Tang, Owen, Mercier, Sarah K., Nasr, Najla, Stern, Josh L., Slobedman, Barry, Driessen, Christoph, Cunningham, Anthony L.

“…Dendritic cells (DCs) play a key role in the pathogenesis of HIV infection. HIV interacts with these cells through 2 pathways in 2 temporal phases, initially…”
Get full text

Efficiently Specified Ventral Midbrain Dopamine Neurons From Human Pluripotent Stem Cells Under Xeno-Free Conditions Restore Motor Deficits in Parkinsonian Rodents by Niclis, Jonathan C, Gantner, Carlos W, Alsanie, Walaa F, McDougall, Stuart J, Bye, Chris R, Elefanty, Andrew G, Stanley, Edouard G, Haynes, John M, Pouton, Colin W, Thompson, Lachlan H, Parish, Clare L

“…: Recent studies have shown evidence for the functional integration of human pluripotent stem cell (hPSC)-derived ventral midbrain dopamine (vmDA) neurons in…”
Get full text

Neuronal activity regulates expression of tyrosine hydroxylase in adult mouse substantia nigra pars compacta neurons: Activity-dependent changes in SNc TH expression by Aumann, Tim D., Egan, Kate, Lim, Jamie, Boon, Wah C., Bye, Chris R., Chua, Hui K., Baban, Natalija, Parish, Clare L., Bobrovskaya, Larisa, Dickson, Phillip, Horne, Malcolm K.

Get full text

Dopamine D 2 receptor knockout mice develop features of Parkinson disease by Tinsley, Rogan B., Bye, Chris R., Parish, Clare L., Tziotis‐Vais, Angela, George, Sonia, Culvenor, Janetta G., Li, Qiao‐Xin, Masters, Colin L., Finkelstein, David I., Horne, Malcolm K.

“…Abstract Objective This study questions whether increased dopamine (DA) turnover in nigral neurons leads to formation of Lewy bodies (LBs), the characteristic…”
Get full text

HIV1―infected dendritic cells show 2 phases of gene expression changes, with lysosomal enzyme activity decreased during the second phase by HARMAN, Andrew N, KRAUS, Marianne, DRIESSEN, Christoph, CUNNINGHAM, Anthony L, BYE, Chris R, BYTH, Karen, TURVILLE, Stuart G, TANG, Owen, MERCIER, Sarah K, NASR, Najla, STERN, Josh L, SLOBEDMAN, Barry

Get full text