Search Results - "Byarugaba, Denis K"
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Towards a bottom-up understanding of antimicrobial use and resistance on the farm: A knowledge, attitudes, and practices survey across livestock systems in five African countries
Published in PloS one (24-01-2020)“…The nutritional and economic potentials of livestock systems are compromised by the emergence and spread of antimicrobial resistance. A major driver of…”
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Whole genome analysis of selected human and animal rotaviruses identified in Uganda from 2012 to 2014 reveals complex genome reassortment events between human, bovine, caprine and porcine strains
Published in PloS one (22-06-2017)“…Rotaviruses of species A (RVA) are a common cause of diarrhoea in children and the young of various other mammals and birds worldwide. To investigate possible…”
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Isolation and characterization of chitosan from Ugandan edible mushrooms, Nile perch scales and banana weevils for biomedical applications
Published in Scientific reports (18-02-2021)“…Of recent, immense attention has been given to chitosan in the biomedical field due to its valuable biochemical and physiological properties. Traditionally,…”
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Potential Sources and Transmission of Salmonella and Antimicrobial Resistance in Kampala, Uganda
Published in PloS one (21-03-2016)“…In sub‒Saharan Africa, non‒typhoidal Salmonellae (NTS) cause invasive disease particularly in children and HIV infected adults, but the disease epidemiology is…”
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Resistome and virulome of high-risk pandemic clones of multidrug-resistant extra-intestinal pathogenic Escherichia coli (ExPEC) isolated from tertiary healthcare settings in Uganda
Published in PloS one (22-11-2023)“…Multi-drug resistant (MDR) globally disseminated extraintestinal pathogenic high-risk Escherichia coli (ExPEC) clones are threatening the gains in bacterial…”
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The history of the emergence and transmission of human coronaviruses
Published in Onderstepoort journal of veterinary research (10-02-2021)“…Human coronaviruses are known respiratory pathogens associated with a range of respiratory illnesses, and there are considerable morbidity and hospitalisation…”
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Phyto-Mediated Copper Oxide Nanoparticles for Antibacterial, Antioxidant and Photocatalytic Performances
Published in Frontiers in bioengineering and biotechnology (16-02-2022)“…The greatest challenge of the current generation and generations to come is antimicrobial resistance, as different pathogenic bacteria have continuously…”
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Molecular characterisation of human adenoviruses associated with respiratory infections in Uganda
Published in BMC infectious diseases (27-06-2023)“…Human adenoviruses (HAdV) are a diverse group of viruses causing a broad range of infections of the respiratory, urogenital and gastrointestinal tracts and…”
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Seroprevalence of human coronaviruses among patients visiting hospital-based sentinel sites in Uganda
Published in BMC infectious diseases (16-06-2021)“…Abstract Background Human coronaviruses are causative agents of respiratory infections with several subtypes being prevalent worldwide. They cause respiratory…”
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Prevalence of pathogenic Klebsiella pneumoniae based on PCR capsular typing harbouring carbapenemases encoding genes in Uganda tertiary hospitals
Published in Antimicrobial resistance & infection control (18-03-2021)“…Klebsiella pneumoniae is an opportunistic pathogen that has been implicated as one of commonest cause of hospital and community acquired infections. The K…”
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Challenges and Solutions to Viral Diseases of Finfish in Marine Aquaculture
Published in Pathogens (Basel) (30-05-2021)“…Aquaculture is the fastest food-producing sector in the world, accounting for one-third of global food production. As is the case with all intensive farming…”
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Detection of drug resistant Mycobacterium tuberculosis by high-throughput sequencing of DNA isolated from acid fast bacilli smears
Published in PloS one (08-05-2020)“…Drug susceptibility testing for Mycobacterium tuberculosis (MTB) is difficult to perform in resource-limited settings where Acid Fast Bacilli (AFB) smears are…”
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Understanding Antimicrobial Use Contexts in the Poultry Sector: Challenges for Small-Scale Layer Farms in Kenya
Published in Antibiotics (Basel) (22-01-2021)“…The poultry sector contributes significantly to Kenya's food and economic security. This contribution is expected to rise dramatically with a growing…”
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Growing problem of multidrug-resistant enteric pathogens in Africa
Published in Emerging infectious diseases (01-11-2007)“…Control of fecal-orally transmitted pathogens is inadequate in many developing countries, in particular, in sub-Saharan Africa. Acquired resistance to…”
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Middle East Respiratory Syndrome Coronavirus (MERS-CoV) in Dromedary Camels in Africa and Middle East
Published in Viruses (05-08-2019)“…Dromedary camels are the natural reservoirs of the Middle East respiratory syndrome coronavirus (MERS-CoV). Camels are mostly bred in East African countries…”
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Serological Surveillance of Influenza D Virus in Ruminants and Swine in West and East Africa, 2017-2020
Published in Viruses (02-09-2021)“…Influenza D virus (IDV) was first isolated in 2011 in Oklahoma, USA from pigs presenting with influenza-like symptoms. IDV is known to mainly circulate in…”
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Next Generation Sequencing and Genetic Analyses Reveal Factors Driving Evolution of Sweetpotato Viruses in Uganda
Published in Pathogens (Basel) (26-09-2024)“…Sweetpotato ( L.) is an essential food crop globally, especially for farmers facing resource limitations. Like other crops, sweetpotato cultivation faces…”
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Genetic Evolution of Avian Influenza A (H9N2) Viruses Isolated from Domestic Poultry in Uganda Reveals Evidence of Mammalian Host Adaptation, Increased Virulence and Reduced Sensitivity to Baloxavir
Published in Viruses (01-09-2022)“…A (H9N2) avian influenza A viruses were first detected in Uganda in 2017 and have since established themselves in live bird markets. The aim of this study was…”
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Whole Genome Sequencing Reveals High Genetic Diversity, Diverse Repertoire of Virulence-Associated Genes and Limited Antibiotic Resistance Genes among Commensal Escherichia coli from Food Animals in Uganda
Published in Microorganisms (Basel) (25-07-2023)“…Commensal Escherichia coli with broad repertoire of virulence and antimicrobial resistance (AMR) genes pose serious public health risks as reservoirs of AMR…”
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Genome Analysis of Klebsiella pneumoniae Reveals International High-Risk Pandemic MDR Clones Emerging in Tertiary Healthcare Settings in Uganda
Published in Pathogens (Basel) (01-11-2023)“…Klebsiella pneumoniae is a threat to public health due to its continued evolution. In this study, we investigated the evolution, convergence, and transmission…”
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