Search Results - "Buzder, Timea"

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    Induction of renal endonuclease G by cisplatin is reduced in DNase I-deficient mice by XIAOYAN YIN, APOSTOLOV, Eugene O, SHAH, Sudhir V, XIAOYING WANG, BOGDANOV, Konstantin V, BUZDER, Timea, STEWART, Anna G, BASNAKIAN, Alexei G

    “…Nephrotoxicity from the chemotherapeutic drug cisplatin is associated with DNA fragmentation and cell death. We have recently demonstrated that DNase I…”
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    Journal Article
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    Uptake of foreign nucleic acids in kidney tubular epithelial cells deficient in proapoptotic endonucleases by Buzder, Timea, Yin, Xiaoyan, Wang, Xiaoying, Banfalvi, Gaspar, Basnakian, Alexei G

    Published in DNA and cell biology (01-09-2009)
    “…Degradation of DNA during gene delivery is an obstacle for gene transfer and for gene therapy. DNases play a major role in degrading foreign DNA. However,…”
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    523. Deoxyribonuclease I and Endonuclease G Are Host Defense Enzymes Responsible for Inactivation of Foreign DNA in Kidney Tubular Epithelial Cells by Buzder, Timea, Yin, Xiaoyan, Wang, Xiaoying, Banfalvi, Gaspar, Basnakian, Alexei G.

    Published in Molecular therapy (01-05-2006)
    “…Gene delivery to kidney cells is essential for the development of gene therapy of nephropathy. Maintaining DNA stability is crucial for successful gene…”
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    Journal Article