Search Results - "Buzas, EI"

Methodological Guidelines to Study Extracellular Vesicles by Coumans, Frank A.W, Brisson, Alain R, Buzas, Edit I, Dignat-George, Françoise, Drees, Esther E.E, El-Andaloussi, Samir, Emanueli, Costanza, Gasecka, Aleksandra, Hendrix, An, Hill, Andrew F, Lacroix, Romaric, Lee, Yi, van Leeuwen, Ton G, Mackman, Nigel, Mäger, Imre, Nolan, John P, van der Pol, Edwin, Pegtel, D Michiel, Sahoo, Susmita, Siljander, Pia R.M, Sturk, Guus, de Wever, Olivier, Nieuwland, Rienk

“…Owing to the relationship between extracellular vesicles (EVs) and physiological and pathological conditions, the interest in EVs is exponentially growing. EVs…”
Get full text

Isolation of Exosomes from Blood Plasma: Qualitative and Quantitative Comparison of Ultracentrifugation and Size Exclusion Chromatography Methods by Baranyai, Tamás, Herczeg, Kata, Onódi, Zsófia, Voszka, István, Módos, Károly, Marton, Nikolett, Nagy, György, Mäger, Imre, Wood, Matthew J, El Andaloussi, Samir, Pálinkás, Zoltán, Kumar, Vikas, Nagy, Péter, Kittel, Ágnes, Buzás, Edit Irén, Ferdinandy, Péter, Giricz, Zoltán

“…Exosomes are emerging targets for biomedical research. However, suitable methods for the isolation of blood plasma-derived exosomes without impurities have not…”
Get full text

Microvesicles in vascular homeostasis and diseases. Position Paper of the European Society of Cardiology (ESC) Working Group on Atherosclerosis and Vascular Biology by Ridger, Victoria C, Boulanger, Chantal M, Angelillo-Scherrer, Anne, Badimon, Lina, Blanc-Brude, Olivier, Bochaton-Piallat, Marie-Luce, Boilard, Eric, Buzas, Edit I, Caporali, Andreas, Dignat-George, Françoise, Evans, Paul C, Lacroix, Romaric, Lutgens, Esther, Ketelhuth, Daniel F J, Nieuwland, Rienk, Toti, Florence, Tunon, Jose, Weber, Christian, Hoefer, Imo E

“…Microvesicles are members of the family of extracellular vesicles shed from the plasma membrane of activated or apoptotic cells. Microvesicles were initially…”
Get more information

Transcriptomic analysis and comparative characterization of rat H9C2, human AC16 and murine HL-1 cardiac cell lines by Gulyas-Onodi, Z, Visnovitz, T, Koncz, A, Varadi, B, Agg, B, Kiss, B, Makkos, A, Nagy, NR, Toth, VE, Leszek, P, Gorbe, A, Giricz, Z, Buzas, EI, Ferdinandy, P, Varga, ZV

“…Abstract Funding Acknowledgements Type of funding sources: Public grant(s) – EU funding. Main funding source(s): European Union's Horizon 2020 research and…”
Get full text

T-cell recognition of differentially tolerated epitopes of cartilage proteoglycan aggrecan in arthritis by Buzás, Edit I., Végvári, Anikó, Murad, Yanal M., Finnegan, Alison, Mikecz, Katalin, Glant, Tibor T.

“…Proteoglycan (PG) aggrecan, a major macromolecular component of cartilage, is highly immunogenic; it induces arthritis in genetically susceptible BALB/c mice…”
Get full text

Elevated levels of synovial fluid antibodies reactive with the small proteoglycans biglycan and decorin in patients with rheumatoid arthritis or other joint diseases by Polgár, A., Falus, A., Koó, É., Ujfalussy, I., Seszták, M., Szűts, I., Konrád, K., Hodinka, L., Bene, É., Mészáros, Gy, Ortutay, Zs, Farkas, É., Paksy, A., Buzás, E. I.

“…Objectives. To determine whether patients with rheumatoid arthritis (RA) express humoral immunity to the small proteoglycans biglycan and decorin and to…”
Get full text

Critical Roles of Glycosaminoglycan Side Chains of Cartilage Proteoglycan (Aggrecan) in Antigen Recognition and Presentation by Glant, Tibor T, Buzas, Edit I, Finnegan, Alison, Negroiu, Gabriela, Cs-Szabo, Gabriella, Mikecz, Katalin

“…Systemic immunization of BALB/c mice with proteoglycan (aggrecan) from fetal human cartilage induces progressive polyarthritis, an experimental disease similar…”
Get full text

Differential Recognition of Altered Peptide Ligands Distinguishes Two Functionally Discordant (Arthritogenic and Nonarthritogenic) Autoreactive T Cell Hybridoma Clones by Buzas, Edit I, Hanyecz, Anita, Murad, Yanal, Hudecz, Ferenc, Rajnavolgyi, Eva, Mikecz, Katalin, Glant, Tibor T

“…Intravenous injection of a cartilage proteoglycan (aggrecan)-specific Th1 hybridoma clone 5/4E8 induced joint lesions similar to those seen in either primary…”
Get full text

A proteoglycan (aggrecan)-specific T cell hybridoma induces arthritis in BALB/c mice by Buzas, EI, Brennan, FR, Mikecz, K, Garzo, M, Negroiu, G, Hollo, K, Cs-Szabo, G, Pintye, E, Glant, TT

“…Aggrecan, the high buoyant density cartilage proteoglycan (PG), has been shown to induce progressive polyarthritis and ankylosing spondylitis in genetically…”
Get full text

Mediators and autopathogenic effector cells in proteoglycan-induced arthritic and clinically asymptomatic BALB/c mice by Buzás, E I, Mikecz, K, Brennan, F R, Glant, T T

“…Proteoglycan (aggrecan)-induced arthritis is an autoimmune inflammatory animal model produced in genetically susceptible BALB/c mice. This animal model shows…”
Get more information

Antigen‐specific B cells present cartilage proteoglycan (aggrecan) to an autoreactive T cell hybridoma derived from a mouse with proteoglycan‐induced arthritis by BRENNAN, F. R., MIKECZ, K., BUZÁS, E. I., RAGASA, D., CS‐SZABÓ, G., NEGROIU, G., GLANT, T. T.

“…SUMMARY Cartilage proteoglycan (aggrecan)‐induced polyarthritis in BALB/c mice is characterized by chronic inflammation and destruction of joint tissues…”
Get full text

Presentation of cartilage proteoglycan to a T cell hybridoma derived from a mouse with proteoglycan‐induced arthritis by BRENNAN, F. R., NEGROIU, G., BUZÁS, E. I., FÜLÖP, C., HOLLÓ, K., MIKECZ, K., GLANT, T. T.

“…SUMMARY Immunization of BALB/c mice with human fetal cartilage proteoglycan (PG) produces progressive polyarthritis, and T ceils play key roles in the…”
Get full text

Effect of pregnancy on proteoglycan‐induced progressive polyarthritis in BALB/c mice: remission of disease activity by BUZÁS, E. I., HOLLÓ, K., RUBLICZKY, L., GARZÓ, M., NYIRKOS, P., GLANT, T. T.

“…SUMMARY Proteoglycan‐induced arthritis is a murine autoimmune model displaying many similarities to human rheumatoid arthritis and ankylosing spondylitis, as…”
Get full text

Interferon-γ but not granulocyte/macrophage colony-stimulating factor augments proteoglycan presentation by synovial cells and chondrocytes to an autopathogenic T cell hybridoma by Brennan, F.R., Mikecz, K., Buzás, E.I., Glant, T.T.

“…Immunization of BALB c mice with human cartilage proteoglycan (aggrecan) produces a progressive polyarthritis, similar in many aspects to human rheumatoid…”
Get full text

Induction of arthritis in HLA–DR4–humanized and HLA–DQ8–humanized mice by human cartilage proteoglycan aggrecan but only in the presence of an appropriate (non‐MHC) genetic background by Szántó, Sándor, Bárdos, Tamás, Szabó, Zoltán, David, Chella S., Buzás, Edit I., Mikecz, Katalin, Glant, Tibor T.

“…Objective To determine whether the rheumatoid arthritis (RA)–predisposing class II molecules of the major histocompatibility complex (MHC) can present…”
Get full text

Synovial fluid exoglycosidases are predictors of rheumatoid arthritis and are effective in cartilage glycosaminoglycan depletion by Ortutay, Zsuzsanna, Polgár, Anna, Gömör, Béla, Géher, Pál, Lakatos, Tamás, Glant, Tibor T., Gay, Renate E., Gay, Steffen, Pállinger, Éva, Farkas, Csaba, Farkas, Éva, Tóthfalusi, László, Kocsis, Katalin, Falus, András, Buzás, Edit I.

“…Objective To analyze enzymes involved in joint damage by simultaneous investigation of glycosidases and matrix metalloproteinases (MMPs) in patients with…”
Get full text

Identification of multiple loci linked to inflammation and autoantibody production by a genome scan of a murine model of rheumatoid arthritis by Otto, Jeffrey M., Cs‐Szabó, Gabriella, Gallagher, Jodi, Velins, Sonja, Mikecz, Katalin, Buzás, Edit I., Enders, Jill T., Li, Yefu, Olsen, Björn R., Glant, Tibor T.

“…Objective Proteoglycan‐induced arthritis (PGIA) is a murine model of rheumatoid arthritis (RA), both in terms of its pathology and its genetics. PGIA can only…”
Get full text