Search Results - "Buyon, J."

Efficacy and safety of subcutaneous tabalumab, a monoclonal antibody to B-cell activating factor, in patients with systemic lupus erythematosus: results from ILLUMINATE-2, a 52-week, phase III, multicentre, randomised, double-blind, placebo-controlled study by Merrill, J T, van Vollenhoven, R F, Buyon, J P, Furie, R A, Stohl, W, Morgan-Cox, M, Dickson, C, Anderson, P W, Lee, C, Berclaz, P-Y, Dörner, T

“…To evaluate the efficacy and safety of tabalumab, a human IgG4 monoclonal antibody that neutralises membrane and soluble B-cell activating factor (BAFF). This…”
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Keeping upbeat to prevent the heartbreak of anti‐Ro/SSA pregnancy by Cuneo, B. F., Buyon, J. P.

“…Linked Comment: Ultrasound Obstet Gynecol 2019; 54: 87–95 Linked Comment: Ultrasound Obstet Gynecol 2019; 54: 87–95…”
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Assessment of flares in lupus patients enrolled in a phase II/III study of rituximab (EXPLORER) by Merrill, JT, Buyon, JP, Furie, RA, Latinis, KM, Gordon, C, Hsieh, H-J, Brunetta, P

“…The EXPLORER study was designed to assess the response to rituximab versus placebo in patients with moderate to severe extrarenal systemic lupus erythematosus…”
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The prevalence and determinants of anti-DFS70 autoantibodies in an international inception cohort of systemic lupus erythematosus patients by Choi, M Y, Clarke, A E, St Pierre, Y, Hanly, J G, Urowitz, M B, Romero-Diaz, J, Gordon, C, Bae, S-C, Bernatsky, S, Wallace, D J, Merrill, J T, Isenberg, D A, Rahman, A, Ginzler, E M, Petri, M, Bruce, I N, Dooley, M A, Fortin, P, Gladman, D D, Sanchez-Guerrero, J, Steinsson, K, Ramsey-Goldman, R, Khamashta, M A, Aranow, C, Alarcón, G S, Manzi, S, Nived, O, Zoma, A A, van Vollenhoven, R F, Ramos-Casals, M, Ruiz-Irastorza, G, Lim, S S, Kalunian, K C, Inanc, M, Kamen, D L, Peschken, C A, Jacobsen, S, Askanase, A, Buyon, J, Mahler, M, Fritzler, M J

“…Autoantibodies to dense fine speckles 70 (DFS70) are purported to rule out the diagnosis of SLE when they occur in the absence of other SLE-related…”
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Disease progression in mothers of children enrolled in the Research Registry for Neonatal Lupus by Rivera, T L, Izmirly, P M, Birnbaum, B K, Byrne, P, Brauth, J B, Katholi, M, Kim, M Y, Fischer, J, Clancy, R M, Buyon, J P

“…To evaluate autoimmune disease progression in asymptomatic and pauci-symptomatic mothers of children with neonatal lupus (NL). Clinical information on mothers…”
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Autoimmune congenital heart block: complex and unusual situations by Brito-Zerón, P, Izmirly, PM, Ramos-Casals, M, Buyon, JP, Khamashta, MA

“…Autoimmune congenital heart block (ACHB) is an immune-mediated cardiac disease included among the manifestations collectively referred to as neonatal lupus…”
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Autoimmune associated congenital heart block: integration of clinical and research clues in the management of the maternal / foetal dyad at risk by Buyon, J. P., Clancy, R. M., Friedman, D. M.

“… One of the strongest associations with autoantibodies directed to components of the SSA/Ro‐SSB/La ribonucleoprotein complex is the development of congenital…”
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Mycophenolate Mofetil or Intravenous Cyclophosphamide for Lupus Nephritis by Ginzler, Ellen M, Dooley, Mary Anne, Aranow, Cynthia, Kim, Mimi Y, Buyon, Jill, Merrill, Joan T, Petri, Michelle, Gilkeson, Gary S, Wallace, Daniel J, Weisman, Michael H, Appel, Gerald B

“…This 24-week randomized, open-label, noninferiority trial compared oral mycophenolate mofetil with monthly intravenous cyclophosphamide as induction therapy…”
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Salivary dysbiosis and the clinical spectrum in anti-Ro positive mothers of children with neonatal lupus by Clancy, R.M., Marion, M.C., Ainsworth, H.C., Blaser, M.J., Chang, M., Howard, T.D., Izmirly, P.M., Lacher, C., Masson, M., Robins, K., Buyon, J.P., Langefeld, C.D.

“…Mothers giving birth to children with manifestations of neonatal lupus (NL) represent a unique population at risk for the development of clinically evident…”
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Antibodies to amino acid 200-239 (p200) of Ro52 as serological markers for the risk of developing congenital heart block by Strandberg, L, Winqvist, O, Sonesson, S.-E, Mohseni, S, Salomonsson, S, Bremme, K, Buyon, J.P, Julkunen, H, Wahren-Herlenius, M

“…Maternal autoantibodies to the p200-epitope of Ro52 have been suggested to correlate with development of congenital heart block. The aim of the present study…”
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Breastfeeding in the systemic lupus erythematosus patient by Francis, A, Nusbaum, J, Melendez Torres, A, Spruill, T, Buyon, J, Mehta-Lee, S

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Study of Flare Assessment in Systemic Lupus Erythematosus Based on Paper Patients by Isenberg, D., Sturgess, J., Allen, E., Aranow, C., Askanase, A., Sang‐Cheol, B., Bernatsky, S., Bruce, I., Buyon, J., Cervera, R., Clarke, A., Dooley, Mary Anne, Fortin, P., Ginzler, E., Gladman, D., Hanly, J., Inanc, M., Jacobsen, S., Kamen, D., Khamashta, M., Lim, S., Manzi, S., Nived, O., Peschken, C., Petri, M., Kalunian, K., Rahman, A., Ramsey‐Goldman, R., Romero‐Diaz, J., Ruiz‐Irastorza, G., Sanchez‐Guerrero, J., Steinsson, K., Sturfelt, G., Urowitz, M., Vollenhoven, R., Wallace, D. J., Zoma, A., Merrill, J., Gordon, C.

“…Objective To determine the level of agreement of disease flare severity (distinguishing severe, moderate, and mild flare and persistent disease activity) in a…”
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Fetal cardiac function assessed by Doppler myocardial performance index (Tei Index) by Friedman, D., Buyon, J., Kim, M., Glickstein, J. S.

“…Objectives The Tei Index (TI) is a useful, non‐invasive, Doppler‐derived myocardial performance tool which can be used to assess aspects of systolic and…”
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Autoimmune-Associated Congenital Heart Block: Demographics, Mortality, Morbidity and Recurrence Rates Obtained From a National Neonatal Lupus Registry by Buyon, Jill P., Hiebert, Rudi, Copel, Joshua, Craft, Joseph, Friedman, Deborah, Katholi, Margaret, Lee, Lela A., Provost, Thomas T., Reichlin, Morris, Rider, Lisa, Rupel, Ann, Saleeb, Susan, Weston, William L., Skovron, Mary Louise

“…Objectives. The present study describes the demographics, mortality, morbidity and recurrence rates of autoimmune-associated congenital heart block (CHB) using…”
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Frequency of neuro-psychiatric dysfunction in anti-SSA/SSB exposed children with and without neonatal lupus by Askanase, AD, Izmirly, PM, Katholi, M., Mumtaz, J., Buyon, JP

“…Neonatal lupus is a model of passively acquired autoimmunity whereby anti-SSA/Ro-SSB/La antibodies target the fetal heart and neonatal skin in a minority of…”
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Autoantibodies in systemic lupus erythematosus: comparison of historical and current assessment of seropositivity by Ippolito, A, Wallace, DJ, Gladman, D, Fortin, PR, Urowitz, M, Werth, V, Costner, M, Gordon, C, Alarcón, GS, Ramsey-Goldman, R, Maddison, P, Clarke, A, Bernatsky, S, Manzi, S, Bae, S-C, Merrill, JT, Ginzler, E, Hanly, JG, Nived, O, Sturfelt, G, Sanchez-Guerrero, J, Bruce, I, Aranow, C, Isenberg, D, Zoma, A, Magder, LS, Buyon, J, Kalunian, K, Dooley, MA, Steinsson, K, Vollenhoven, RF van, Stoll, T, Weisman, M, Petri, M

“…Systemic lupus erythematosus (SLE) is characterized by multiple autoantibodies and complement activation. Recent studies have suggested that anti-nuclear…”
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Discordant spectrum of cardiac manifestations of neonatal lupus in twins by Killen, SAS, Buyon, JP, Friedman, DM

“…Congenital complete heart block associated with transplacental passage of maternal autoantibodies reactive with SSA/Ro and SSB/La is a rare disease with…”
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Different temporal expression of immunodominant Ro60/60 kDa-SSA and La/SSB apotopes by Reed, J.H, Neufing, P.J, Jackson, M.W, Clancy, R.M, Macardle, P.J, Buyon, J.P, Gordon, T.P

“…Opsonization of apoptotic cardiocytes by maternal anti-Ro/SSA and anti-La/SSB antibodies contributes to tissue injury in the neonatal lupus syndrome. The…”
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Clinical manifestations and coronary artery disease risk factors at diagnosis of systemic lupus erythematosus: data from an international inception cohort by Urowitz, M.B., Gladman, D., Ibañez, D., Fortin, P., Sanchez-Guerrero, J., Bae, S., Clarke, A., Bernatsky, S., Gordon, C., Hanly, J., Wallace, D., Isenberg, D., Ginzler, E., Merrill, J., Alarcon, G., Steinsson, K., Petri, M., Dooley, M.A., Bruce, I., Manzi, S., Khamashta, M., Ramsey-Goldman, R., Zoma, A., Sturfelt, G., Nived, O., Maddison, P., Font, J., van Vollenhoven, R., Aranow, C., Kalunian, K., Stoll, T., Buyon, J.

“…Systemic Lupus International Collaborating Clinics (SLICC) comprises 27 centres from 11 countries. An inception cohort of 918 SLE patients has been assembled…”
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Autoantibody-associated congenital heart block : outcome in mothers and children by WALTUCK, J, BUYON, J. P

“…To determine the initial clinical status and the long-term outcome of mothers and their children with autoantibody-associated congenital heart block. Dynamic,…”
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