Search Results - "Buxton, R. S."

Striate palmoplantar keratoderma arising from desmoplakin and desmoglein 1 mutations is associated with contrasting perturbations of desmosomes and the keratin filament network by Wan, H., Dopping-Hepenstal, P.J.C., Gratian, M.J., Stone, M.G., Zhu, G., Purkis, P.E., South, A.P., Keane, F., Armstrong, D.K.B., Buxton, R.S., McGrath, J.A., Eady, R.A.J.

“…Summary Background  Several hereditary human diseases are now known to be caused by distinct mutations in genes encoding various desmosome components. Although…”
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Parasite plastids: maintenance and functions by Wilson, R. J. M. (Iain), Rangachari, K., Saldanha, J. W., Rickman, L., Buxton, R. S., Eccleston, J. F.

“…genes have emerged only recently and point to the areas of iron homeostasis, [Fe–S] cluster formation and oxidative stress. We present experimental evidence…”
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Nomenclature of the Desmosomal Cadherins by Buxton, R. S., Cowin, P., Franke, W. W., Garrod, D. R., Green, K. J., King, I. A., Koch, P. J., Magee, A. I., Rees, D. A., Stanley, J. R., Steinberg, M. S.

“…The results of cDNA cloning and sequencing have established that the major glycoproteins of the desmosome type of cell-cell junctions are members of the…”
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Clustered Cadherin Genes: A Sequence-Ready Contig for the Desmosomal Cadherin Locus on Human Chromosome 18 by Hunt, Debbie M., Sahota, Virender K., Taylor, Kay, Šimrak, Danijela, Hornigold, Nick, Arnemann, Joachim, Wolfe, Jonathan, Buxton, Roger S.

“…We describe the assembly of a cosmid and PAC contig of approximately 700 kb on human chromosome 18q12 spanning the DSC and DSG genes coding for the…”
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Desmosomal Glycoprotein DGI, a Component of Intercellular Desmosome Junctions, is Related to the Cadherin Family of Cell Adhesion Molecules by Wheeler, G. N., Parker, A. E., Thomas, C. L., Ataliotis, P., Poynter, D., Arnemann, J., Rutman, A. J., Pidsley, S. C., Watt, F. M., Rees, D. A., Buxton, R. S., Magee, A. I.

“…Among the variety of specialized intercellular junctions, those of the adherens type have the most obvious association with cytoskeletal elements. This may be…”
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Hierarchical expression of desmosomal cadherins during stratified epithelial morphogenesis in the mouse by King, Ian A., Angst, Brigitt D., Hunt, Debbie M., Buxton, Roger S., Kruger, Marion, Arnemann, Joachim

“…Desmosomes contain two heterogeneous families of specialized cadherins (desmogleins or Dsgs and desmocollins or Dscs), subtypes of which are known to be…”
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The majority of inducible DNA repair genes in Mycobacterium tuberculosis are induced independently of RecA by Rand, Lucinda, Hinds, Jason, Springer, Burkhard, Sander, Peter, Buxton, Roger S., Davis, Elaine O.

“…Summary In many species of bacteria most inducible DNA repair genes are regulated by LexA homologues and are dependent on RecA for induction. We have shown…”
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The plakophilin 1 (PKP1) and plakoglobin (JUP) genes map to human chromosomes 1q and 17, respectively by COWLEY, C. M. E, SIMRAK, D, SPURR, N. K, ARNEMANN, J, BUXTON, R. S

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Desmosomal glycoproteins II and III. Cadherin-like junctional molecules generated by alternative splicing by PARKER, A. E, WHEELER, G. N, ARNEMANN, J, PIDSLEY, S. C, ATALIOTIS, P, THOMAS, C. L, REES, D. A, MAGEE, A. I, BUXTON, R. S

“…We have cloned the human genes coding for desmosomal glycoproteins DGII and DGIII, found in desmosomal cell junctions, and sequencing shows that they are…”
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The Regulatory Region of the Human Desmocollin 3 Promoter Forms a DNA Four-Way Junction by Gadhavi, Paresh L., Greenwood, Matthew D., Strom, Molly, King, Ian A., Buxton, Roger S.

“…Adhesion between desmosomal junctions is mediated by structural proteins of the cadherin family, viz. three desmocollins (DSC) and three desmogleins (DSG)…”
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DNA sequence analysis of the dye gene of Escherichia coli reveals amino acid homology between the dye and OmpR proteins by Drury, L S, Buxton, R S

“…Mutation of the dye gene of Escherichia coli results in sensitivity of dyes, envelope protein changes, loss of expression of alkaline phosphatase, and reduced…”
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A YAC Contig Joining the Desmocollin and Desmoglein Loci on Human Chromosome 18 and Ordering of the Desmocollin Genes by Cowley, Catherine M.E., Simrak, Danijela, Marsden, Mark D., King, Ian A., Arnemann, Joachim, Buxton, Roger S.

“…The desmocollins and desmogleins are members of the cadherin family of adhesive proteins present in the desmosome type of cell–cell junction. All of the known…”
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Tandem arrangement of the closely linked desmoglein genes on human chromosome 18 by Simrak, Danijela, Cowley, Catherine M.E., Buxton, Roger S., Arnemann, Joachim

“…The desmogleins, together with the desmocollins, both members of the cadherin superfamily, are the adhesive proteins of the desmosome type of cell junction,…”
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Exon–Intron Organization of the Human Type 2 Desmocollin Gene (DSC2): Desmocollin Gene Structure Is Closer to “Classical” Cadherins Than to Desmogleins by Greenwood, Matthew D., Marsden, Mark D., Cowley, Catherine M.E., Sahota, Virender K., Buxton, Roger S.

“…The cadherins are a superfamily of calcium-dependent glycoproteins that are cell adhesion molecules. Two families of cadherins, the desmocollins (Dsc) and…”
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A two-component signal transduction system with a PAS domain-containing sensor is required for virulence of Mycobacterium tuberculosis in mice by Rickman, Lisa, Saldanha, José W, Hunt, Debbie M, Hoar, Dominic N, Colston, M.Joseph, Millar, Jonathan B.A, Buxton, Roger S

“…Mycobacterium tuberculosis, the causative organism of tuberculosis, encounters oxidative stress during phagocytosis by the macrophage and following macrophage…”
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Cloning of the cDNA (DSC1) coding for human type 1 desmocollin and its assignment to chromosome 18 by King, I A, Arnemann, J, Spurr, N K, Buxton, R S

“…Desmosomes are adhesive epithelial junctions that contain two distinct classes of cadherin-related glycoproteins (desmogleins and desmocollins), both of which…”
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Chromosomal assignment of the human genes coding for the major proteins of the desmosome junction, desmoglein DGI (DSG), desmocollins DGII/III (DSC), desmoplakins DPI/II (DSP), and plakoglobin DPIII (JUP) by Arnemann, J, Spurr, N K, Wheeler, G N, Parker, A E, Buxton, R S

“…We have established PCR assays for the genes coding for the major proteins of the desmosome type of cell junction, the desmosomal cadherins DGI (desmoglein)…”
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N-Terminal Deletion in a Desmosomal Cadherin Causes the Autosomal Dominant Skin Disease Striate Palmoplantar Keratoderma by Rickman, Lisa, Šimrak, Danijela, Stevens, Howard P., Hunt, Debbie M., King, Ian A., Bryant, Stephen P., Eady, Robin A.J., Leigh, Irene M., Arnemann, Joachim, Magee, Anthony I., Kelsell, David P., Buxton, Roger S.

“…The N-terminal extracellular domain of the cadherins, calcium-dependent cell adhesion molecules, has been shown by X-ray crystallography to be involved in two…”
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Extracellularly truncated desmoglein 1 compromises desmosomes in MDCK cells by Serpente, N, Marcozzi, C, Roberts, G A, Bao, Q, Angst, B D, Hirst, E M, Burdett, I D, Buxton, R S, Magee, A I

“…The formation and stability of epithelial tissue involves cell adhesion and the connection of the intermediate filaments of contiguous cells, mediated by…”
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Visualisation by electron microscopy of the unique part of the cytoplasmic domain of a desmoglein, a cadherin-like protein of the desmosome type of cell junction by Rutman, A.J., Buxton, R.S., Burdett, I.D.J.

“…Part of the cytoplasmic domain of a human desmoglein, Dsgl, a cadherin-like protein found in desmosomes of epithelial cells, has been visualised by electron…”
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