Search Results - "Buxbaum, Adina R"

In the right place at the right time: visualizing and understanding mRNA localization by Buxbaum, Adina R., Haimovich, Gal, Singer, Robert H.

“…Key Points The asymmetrical distribution of mRNAs in cells is used by various organisms to spatially control gene expression. RNA localization has a role in…”
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Glutamate-induced RNA localization and translation in neurons by Yoon, Young J., Wu, Bin, Buxbaum, Adina R., Das, Sulagna, Tsai, Albert, English, Brian P., Grimm, Jonathan B., Lavis, Luke D., Singer, Robert H.

“…Localization of mRNA is required for protein synthesis to occur within discrete intracellular compartments. Neurons represent an ideal system for studying the…”
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Quantifying Protein-mRNA Interactions in Single Live Cells by Wu, Bin, Buxbaum, Adina R., Katz, Zachary B., Yoon, Young J., Singer, Robert H.

“…Specific binding proteins are crucial for the correct spatiotemporal expression of mRNA. To understand this process, a method is required to characterize…”
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mRNA on the Move: The Road to Its Biological Destiny by Eliscovich, Carolina, Buxbaum, Adina R., Katz, Zachary B., Singer, Robert H.

“…Cells have evolved to regulate the asymmetric distribution of specific mRNA targets to institute spatial and temporal control over gene expression. Over the…”
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Spatial arrangement of an RNA zipcode identifies mRNAs under post-transcriptional control by Patel, Vivek L, Mitra, Somdeb, Harris, Richard, Buxbaum, Adina R, Lionnet, Timothée, Brenowitz, Michael, Girvin, Mark, Levy, Matthew, Almo, Steven C, Singer, Robert H, Chao, Jeffrey A

“…How RNA-binding proteins recognize specific sets of target mRNAs remains poorly understood because current approaches depend primarily on sequence information…”
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Sam68 Enables Metabotropic Glutamate Receptor-Dependent LTD in Distal Dendritic Regions of CA1 Hippocampal Neurons by Klein, Matthew E., Younts, Thomas J., Cobo, Carmen Freire, Buxbaum, Adina R., Aow, Jonathan, Erdjument-Bromage, Hediye, Richard, Stéphane, Malinow, Roberto, Neubert, Thomas A., Singer, Robert H., Castillo, Pablo E., Jordan, Bryen A.

“…The transport and translation of dendritic mRNAs by RNA-binding proteins (RBPs) allows for spatially restricted gene expression in neuronal processes. Although…”
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Single β-Actin mRNA Detection in Neurons Reveals a Mechanism for Regulating Its Translatability by Buxbaum, Adina R., Wu, Bin, Singer, Robert H.

“…The physical manifestation of learning and memory formation in the brain can be expressed by strengthening or weakening of synaptic connections through…”
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Single-molecule insights into mRNA dynamics in neurons by Buxbaum, Adina R, Yoon, Young J, Singer, Robert H, Park, Hye Yoon

“…Highlights • mRNA localization into neuronal processes and localized translation is an efficient mechanism of local protein delivery in neurons due to their…”
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Tagged actin mRNA dysregulation in IGF2BP1[Formula: see text] mice by Núñez, Leti, Buxbaum, Adina R, Katz, Zachary B, Lopez-Jones, Melissa, Nwokafor, Chiso, Czaplinski, Kevin, Pan, Feng, Rosenberg, Jason, Monday, Hannah R, Singer, Robert H

“…Gene expression is tightly regulated by RNA-binding proteins (RBPs) to facilitate cell survival, differentiation, and migration. Previous reports have shown…”
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CPEB3-dependent increase in GluA2 subunits impairs excitatory transmission onto inhibitory interneurons in a mouse model of fragile X by Hwang, Jee-Yeon, Monday, Hannah R, Yan, Jingqi, Gompers, Andrea, Buxbaum, Adina R, Sawicka, Kirsty J, Singer, Robert H, Castillo, Pablo E, Zukin, R Suzanne

“…Fragile X syndrome (FXS) is a leading cause of inherited intellectual disability and autism. Whereas dysregulated RNA translation in Fmr1 knockout (KO) mice, a…”
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In the right place at the right time: visualizing and understanding mRNA localization by Buxbaum, Adina R, Haimovich, Gal, Singer, Robert H

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Macrophages create an acidic extracellular hydrolytic compartment to digest aggregated lipoproteins by Haka, Abigail S, Grosheva, Inna, Chiang, Ethan, Buxbaum, Adina R, Baird, Barbara A, Pierini, Lynda M, Maxfield, Frederick R

“…A critical event in atherogenesis is the interaction of macrophages with subendothelial lipoproteins. Although most studies model this interaction by…”
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Single mRNA tracking in live cells by Park, Hye Yoon, Buxbaum, Adina R, Singer, Robert H

“…Asymmetric distribution of mRNA is a prevalent phenomenon observed in diverse cell types. The posttranscriptional movement and localization of mRNA provides an…”
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Tagged actin mRNA dysregulation in IGF2BP1Formula: see text mice by Núñez, Leti, Buxbaum, Adina R, Katz, Zachary B, Lopez-Jones, Melissa, Nwoka, Chiso, Czaplinski, Kevin, Pan, Feng, Rosenberg, Jason, Monday, Hannah R, Singer, Robert H

“…Gene expression is tightly regulated by RNA-binding proteins (RBPs) to facilitate cell survival, differentiation, and migration. Previous reports have shown…”
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Erratum: In the right place at the right time: visualizing and understanding mRNA localization by Buxbaum, Adina R., Haimovich, Gal, Singer, Robert H.

“…Nature Reviews Molecular Cell Biology 16, 95–109 (2015) In the original article, the two reference citations in the following sentence were incorrect: “…”
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Single [beta]-Actin mRNA Detection in Neurons Reveals a Mechanism for Regulating Its Translatability by Buxbaum, Adina R, Wu, Bin, Singer, Robert H

“…The physical manifestation of learning and memory formation in the brain can be expressed by strengthening or weakening of synaptic connections through…”
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Macrophages Create a Lysosomal Synapse to Digest Aggregated Lipoproteins by Haka, Abigail S., Grosheva, Inna, Chiang, Ethan, Buxbaum, Adina R., Baird, Barbara A., Pierini, Lynda M., Maxfield, Frederick R.

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Spatial & temporal regulation of β-actin mRNA local translation in neurons by Buxbaum, Adina R

“…The physical manifestation of learning and memory formation in the brain can be expressed by strengthening or weakening of synaptic connections through…”
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P-161: Amyloid beta (Aβ) is unaltered with highly elevated peripheral cholesterol in mice lacking the low-density lipoprotein receptor by Franciosi, Sonia, English, Daniel, Cho, Julie, Buxbaum, Adina R., Schmidt, Stephen D., Perez, Gissel, Mathews, Paul M., De Gasperi, Rita, Sosa, Miguel A. Gama, Haroutunian, Vahram, Elder, Gregory A., Buxbaum, Joseph D.

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P-161 by Franciosi, Sonia, English, Daniel, Cho, Julie, Buxbaum, Adina R, Schmidt, Stephen D, Perez, Gissel, Mathews, Paul M, De Gasperi, Rita, Sosa, Miguel A. Gama, Haroutunian, Vahram, Elder, Gregory A, Buxbaum, Joseph D

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