Search Results - "Butzloff, Sabine"

Oligomeric interfaces as a tool in drug discovery: Specific interference with activity of malate dehydrogenase of Plasmodium falciparum in vitro by Lunev, Sergey, Butzloff, Sabine, Romero, Atilio R, Linzke, Marleen, Batista, Fernando A, Meissner, Kamila A, Müller, Ingrid B, Adawy, Alaa, Wrenger, Carsten, Groves, Matthew R

“…Malaria remains a major threat to human health, as strains resistant to current therapeutics are discovered. Efforts in finding new drug targets are hampered…”
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Oligomeric protein interference validates druggability of aspartate interconversion in Plasmodium falciparum by Batista, Fernando A., Bosch, Soraya S., Butzloff, Sabine, Lunev, Sergey, Meissner, Kamila A., Linzke, Marleen, Romero, Atilio R., Wang, Chao, Müller, Ingrid B., Dömling, Alexander S. S., Groves, Matthew R., Wrenger, Carsten

“…The appearance of multi‐drug resistant strains of malaria poses a major challenge to human health and validated drug targets are urgently required. To define a…”
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The antioxidative effect of de novo generated vitamin B6 in Plasmodium falciparum validated by protein interference by Knöckel, Julia, Müller, Ingrid B, Butzloff, Sabine, Bergmann, Bärbel, Walter, Rolf D, Wrenger, Carsten

“…The malaria parasite Plasmodium falciparum is able to synthesize de novo PLP (pyridoxal 5'-phosphate), the active form of vitamin B6. In the present study, we…”
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Cytometric quantification of singlet oxygen in the human malaria parasite Plasmodium falciparum by Butzloff, Sabine, Groves, Matthew R., Wrenger, Carsten, Müller, Ingrid B.

“…The malaria parasite Plasmodium falciparum proliferates within human erythrocytes and is thereby exposed to a variety of reactive oxygen species (ROS) such as…”
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Crystallization and preliminary X-ray diffraction of malate dehydrogenase from Plasmodium falciparum by Wrenger, Carsten, Müller, Ingrid B., Butzloff, Sabine, Jordanova, Rositsa, Lunev, Sergey, Groves, Matthew R.

“…The expression, purification, crystallization and preliminary X‐ray diffraction characterization of malate dehydrogenase (MDH) from the malarial parasite…”
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