Search Results - "Butty, Vincent L"

Braveheart, a Long Noncoding RNA Required for Cardiovascular Lineage Commitment by Klattenhoff, Carla A., Scheuermann, Johanna C., Surface, Lauren E., Bradley, Robert K., Fields, Paul A., Steinhauser, Matthew L., Ding, Huiming, Butty, Vincent L., Torrey, Lillian, Haas, Simon, Abo, Ryan, Tabebordbar, Mohammadsharif, Lee, Richard T., Burge, Christopher B., Boyer, Laurie A.

“…Long noncoding RNAs (lncRNAs) are often expressed in a development-specific manner, yet little is known about their roles in lineage commitment. Here,…”
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The endoplasmic reticulum proteostasis network profoundly shapes the protein sequence space accessible to HIV envelope by Yoon, Jimin, Nekongo, Emmanuel E, Patrick, Jessica E, Hui, Tiffani, Phillips, Angela M, Ponomarenko, Anna I, Hendel, Samuel J, Sebastian, Rebecca M, Zhang, Yu Meng, Butty, Vincent L, Ogbunugafor, C Brandon, Lin, Yu-Shan, Shoulders, Matthew D

“…The sequence space accessible to evolving proteins can be enhanced by cellular chaperones that assist biophysically defective clients in navigating complex…”
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Global transcriptional regulation of innate immunity by ATF-7 in C. elegans by Fletcher, Marissa, Tillman, Erik J, Butty, Vincent L, Levine, Stuart S, Kim, Dennis H

“…The nematode Caenorhabditis elegans has emerged as a genetically tractable animal host in which to study evolutionarily conserved mechanisms of innate immune…”
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H3K27me3-mediated silencing of structural genes is required for zebrafish heart regeneration by Ben-Yair, Raz, Butty, Vincent L, Busby, Michele, Qiu, Yutong, Levine, Stuart S, Goren, Alon, Boyer, Laurie A, Burns, C Geoffrey, Burns, Caroline E

“…Deciphering the genetic and epigenetic regulation of cardiomyocyte proliferation in organisms that are capable of robust cardiac renewal, such as zebrafish,…”
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Transcriptional Reversion of Cardiac Myocyte Fate During Mammalian Cardiac Regeneration by O’Meara, Caitlin C, Wamstad, Joseph A, Gladstone, Rachel A, Fomovsky, Gregory M, Butty, Vincent L, Shrikumar, Avanti, Gannon, Joseph B, Boyer, Laurie A, Lee, Richard T

“…RATIONALE:Neonatal mice have the capacity to regenerate their hearts in response to injury, but this potential is lost after the first week of life. The…”
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Multiplexed DNA repair assays for multiple lesions and multiple doses via transcription inhibition and transcriptional mutagenesis by Nagel, Zachary D., Margulies, Carrie M., Chaim, Isaac A., McRee, Siobhan K., Mazzucato, Patrizia, Ahmad, Anwaar, Abo, Ryan P., Butty, Vincent L., Forget, Anthony L., Samson, Leona D.

“…The capacity to repair different types of DNA damage varies among individuals, making them more or less susceptible to the detrimental health consequences of…”
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An Adaptable Platform for Directed Evolution in Human Cells by Berman, Chet M, Papa, Louis J, Hendel, Samuel J, Moore, Christopher L, Suen, Patreece H, Weickhardt, Alexander F, Doan, Ngoc-Duc, Kumar, Caiden M, Uil, Taco G, Butty, Vincent L, Hoeben, Robert C, Shoulders, Matthew D

“…The discovery and optimization of biomolecules that reliably function in metazoan cells is imperative for both the study of basic biology and the treatment of…”
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HRI coordinates translation necessary for protein homeostasis and mitochondrial function in erythropoiesis by Zhang, Shuping, Macias-Garcia, Alejandra, Ulirsch, Jacob C, Velazquez, Jason, Butty, Vincent L, Levine, Stuart S, Sankaran, Vijay G, Chen, Jane-Jane

“…Iron and heme play central roles in the production of red blood cells, but the underlying mechanisms remain incompletely understood. Heme-regulated eIF2α…”
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A Method for Selective Depletion of Zn(II) Ions from Complex Biological Media and Evaluation of Cellular Consequences of Zn(II) Deficiency by Richardson, Christopher E. R, Cunden, Lisa S, Butty, Vincent L, Nolan, Elizabeth M, Lippard, Stephen J, Shoulders, Matthew D

“…We describe the preparation, evaluation, and application of an S100A12 protein-conjugated solid support, hereafter the “A12-resin”, that can remove 99% of…”
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Destabilized adaptive influenza variants critical for innate immune system escape are potentiated by host chaperones by Phillips, Angela M, Ponomarenko, Anna I, Chen, Kenny, Ashenberg, Orr, Miao, Jiayuan, McHugh, Sean M, Butty, Vincent L, Whittaker, Charles A, Moore, Christopher L, Bloom, Jesse D, Lin, Yu-Shan, Shoulders, Matthew D

“…The threat of viral pandemics demands a comprehensive understanding of evolution at the host-pathogen interface. Here, we show that the accessibility of…”
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Cross-site comparison of ribosomal depletion kits for Illumina RNAseq library construction by Herbert, Zachary T, Kershner, Jamie P, Butty, Vincent L, Thimmapuram, Jyothi, Choudhari, Sulbha, Alekseyev, Yuriy O, Fan, Jun, Podnar, Jessica W, Wilcox, Edward, Gipson, Jenny, Gillaspy, Allison, Jepsen, Kristen, BonDurant, Sandra Splinter, Morris, Krystalynne, Berkeley, Maura, LeClerc, Ashley, Simpson, Stephen D, Sommerville, Gary, Grimmett, Leslie, Adams, Marie, Levine, Stuart S

“…Ribosomal RNA (rRNA) comprises at least 90% of total RNA extracted from mammalian tissue or cell line samples. Informative transcriptional profiling using…”
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H2A.Z acidic patch couples chromatin dynamics to regulation of gene expression programs during ESC differentiation by Subramanian, Vidya, Mazumder, Aprotim, Surface, Lauren E, Butty, Vincent L, Fields, Paul A, Alwan, Allison, Torrey, Lillian, Thai, Kevin K, Levine, Stuart S, Bathe, Mark, Boyer, Laurie A

“…The histone H2A variant H2A.Z is essential for embryonic development and for proper control of developmental gene expression programs in embryonic stem cells…”
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Enhanced ER proteostasis and temperature differentially impact the mutational tolerance of influenza hemagglutinin by Phillips, Angela M, Doud, Michael B, Gonzalez, Luna O, Butty, Vincent L, Lin, Yu-Shan, Bloom, Jesse D, Shoulders, Matthew D

“…We systematically and quantitatively evaluate whether endoplasmic reticulum (ER) proteostasis factors impact the mutational tolerance of secretory pathway…”
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Alternative RNA splicing in the endothelium mediated in part by Rbfox2 regulates the arterial response to low flow by Murphy, Patrick A, Butty, Vincent L, Boutz, Paul L, Begum, Shahinoor, Kimble, Amy L, Sharp, Phillip A, Burge, Christopher B, Hynes, Richard O

“…Low and disturbed blood flow drives the progression of arterial diseases including atherosclerosis and aneurysms. The endothelial response to flow and its…”
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Host proteostasis modulates influenza evolution by Phillips, Angela M, Gonzalez, Luna O, Nekongo, Emmanuel E, Ponomarenko, Anna I, McHugh, Sean M, Butty, Vincent L, Levine, Stuart S, Lin, Yu-Shan, Mirny, Leonid A, Shoulders, Matthew D

“…Predicting and constraining RNA virus evolution require understanding the molecular factors that define the mutational landscape accessible to these pathogens…”
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Polycomb Repressive Complex 2 regulates lineage fidelity during embryonic stem cell differentiation by Thornton, Seraphim R, Butty, Vincent L, Levine, Stuart S, Boyer, Laurie A

“…Polycomb Repressive Complex 2 (PRC2) catalyzes histone H3 lysine 27 tri-methylation (H3K27me3), an epigenetic modification associated with gene repression…”
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Single-cell transcriptomic profiling of the aging mouse brain by Ximerakis, Methodios, Lipnick, Scott L., Innes, Brendan T., Simmons, Sean K., Adiconis, Xian, Dionne, Danielle, Mayweather, Brittany A., Nguyen, Lan, Niziolek, Zachary, Ozek, Ceren, Butty, Vincent L., Isserlin, Ruth, Buchanan, Sean M., Levine, Stuart S., Regev, Aviv, Bader, Gary D., Levin, Joshua Z., Rubin, Lee L.

“…The mammalian brain is complex, with multiple cell types performing a variety of diverse functions, but exactly how each cell type is affected in aging remains…”
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Digital Genotyping and Haplotyping with Polymerase Colonies by Mitra, Robi D., Butty, Vincent L., Shendure, Jay, Williams, Benjamin R., Housman, David E., Church, George M.

“…Polymerase colony (polony) technology amplifies multiple individual DNA molecules within a thin acrylamide gel attached to a microscope slide. Each DNA…”
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Ketone Body Signaling Mediates Intestinal Stem Cell Homeostasis and Adaptation to Diet by Cheng, Chia-Wei, Biton, Moshe, Haber, Adam L., Gunduz, Nuray, Eng, George, Gaynor, Liam T., Tripathi, Surya, Calibasi-Kocal, Gizem, Rickelt, Steffen, Butty, Vincent L., Moreno-Serrano, Marta, Iqbal, Ameena M., Bauer-Rowe, Khristian E., Imada, Shinya, Ulutas, Mehmet Sefa, Mylonas, Constantine, Whary, Mark T., Levine, Stuart S., Basbinar, Yasemin, Hynes, Richard O., Mino-Kenudson, Mari, Deshpande, Vikram, Boyer, Laurie A., Fox, James G., Terranova, Christopher, Rai, Kunal, Piwnica-Worms, Helen, Mihaylova, Maria M., Regev, Aviv, Yilmaz, Ömer H.

“…Little is known about how metabolites couple tissue-specific stem cell function with physiology. Here we show that, in the mammalian small intestine, the…”
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In Vitro Culture, Drug Sensitivity, and Transcriptome of Plasmodium Vivax Hypnozoites by Gural, Nil, Mancio-Silva, Liliana, Miller, Alex B., Galstian, Ani, Butty, Vincent L., Levine, Stuart S., Patrapuvich, Rapatbhorn, Desai, Salil P., Mikolajczak, Sebastian A., Kappe, Stefan H.I., Fleming, Heather E., March, Sandra, Sattabongkot, Jetsumon, Bhatia, Sangeeta N.

“…The unique relapsing nature of Plasmodium vivax infection is a major barrier to malaria eradication. Upon infection, dormant liver-stage forms, hypnozoites,…”
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