Search Results - "Butti, Erica"
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Endogenous neural stem cells characterization using omics approaches: Current knowledge in health and disease
Published in Frontiers in cellular neuroscience (05-04-2023)“…Neural stem cells (NSCs), an invaluable source of neuronal and glial progeny, have been widely interrogated in the last twenty years, mainly to understand…”
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Neural Stem Cell Transplantation Induces Stroke Recovery by Upregulating Glutamate Transporter GLT-1 in Astrocytes
Published in The Journal of neuroscience (12-10-2016)“…Ischemic stroke is the leading cause of disability, but effective therapies are currently widely lacking. Recovery from stroke is very much dependent on the…”
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Inflammation Triggers Synaptic Alteration and Degeneration in Experimental Autoimmune Encephalomyelitis
Published in The Journal of neuroscience (18-03-2009)“…Neurodegeneration is the irremediable pathological event occurring during chronic inflammatory diseases of the CNS. Here we show that, in experimental…”
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Neural precursor cells tune striatal connectivity through the release of IGFBPL1
Published in Nature communications (08-12-2022)“…The adult brain retains over life endogenous neural stem/precursor cells (eNPCs) within the subventricular zone (SVZ). Whether or not these cells exert…”
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In vivo fate analysis reveals the multipotent and self-renewal features of embryonic AspM expressing cells
Published in PloS one (29-04-2011)“…Radial Glia (RG) cells constitute the major population of neural progenitors of the mouse developing brain. These cells are located in the ventricular zone…”
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Endogenous neural precursor cells in health and disease
Published in Brain research (01-03-2020)“…•Neural precursor cells accomplish important functions for brain tissue homeostasis.•Neural precursor cells provide new cells for the olfactory bulb and…”
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A nitric oxide releasing derivative of flurbiprofen inhibits experimental autoimmune encephalomyelitis
Published in Journal of neuroimmunology (01-05-2004)“…Nitric oxide (NO)-releasing non-steroidal anti-inflammatory drugs (NSAIDs) have been reported to have a safer profile and additional anti-inflammatory and…”
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Neural Stem Cells of the Subventricular Zone Contribute to Neuroprotection of the Corpus Callosum after Cuprizone-Induced Demyelination
Published in The Journal of neuroscience (10-07-2019)“…Myelin loss occurring in demyelinating diseases, including multiple sclerosis, is the leading cause of long-lasting neurological disability in adults. While…”
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Neurogenesis or non-neurogenesis: that is the question
Published in The Journal of clinical investigation (01-03-2014)“…Neural stem/precursor cells (NPCs) that reside within germinal niches of the adult CNS have more complex roles than previously expected. In addition to their…”
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Age-induced alterations of granulopoiesis generate atypical neutrophils that aggravate stroke pathology
Published in Nature immunology (01-06-2023)“…Aging accounts for increased risk and dismal outcome of ischemic stroke. Here, we investigated the impact of age-related changes in the immune system on…”
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Neural precursor cell-secreted TGF-β2 redirects inflammatory monocyte-derived cells in CNS autoimmunity
Published in The Journal of clinical investigation (01-11-2017)“…In multiple sclerosis, the pathological interaction between autoreactive Th cells and mononuclear phagocytes in the CNS drives initiation and maintenance of…”
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Neural precursor cells rescue symptoms of Rett syndrome by activation of the Interferon γ pathway
Published in EMBO molecular medicine (20-09-2024)“…The beneficial effects of Neural Precursor Cell (NPC) transplantation in several neurological disorders are well established and they are generally mediated by…”
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Neurogenic and non-neurogenic functions of endogenous neural stem cells
Published in Frontiers in neuroscience (29-04-2014)“…Adult neurogenesis is a lifelong process that occurs in two main neurogenic niches of the brain, namely in the subventricular zone (SVZ) of the lateral…”
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Persistent modification of forebrain networks and metabolism in rats following adolescent exposure to a 5-HT7 receptor agonist
Published in Psychopharmacology (2015)“…Rationale The serotonin 7 receptor (5-HT7-R) is part of a neuro-transmission system with a proposed role in neural plasticity and in mood, cognitive or sleep…”
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Harmonization of sensorimotor deficit assessment in a registered multicentre pre-clinical randomized controlled trial using two models of ischemic stroke
Published in Journal of cerebral blood flow and metabolism (01-07-2023)“…Multicentre preclinical randomized controlled trials (pRCTs) are a valuable tool to improve experimental stroke research, but are challenging and therefore…”
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Subventricular zone neural progenitors protect striatal neurons from glutamatergic excitotoxicity
Published in Brain (London, England : 1878) (01-11-2012)“…The functional significance of adult neural stem and progenitor cells in hippocampal-dependent learning and memory has been well documented. Although adult…”
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Neural precursor cell-secreted TGF-[beta]2 redirects inflammatory monocyte-derived cells in CNS autoimmunity
Published in The Journal of clinical investigation (01-11-2017)“…In multiple sclerosis, the pathological interaction between autoreactive Th cells and mononuclear phagocytes in the CNS drives initiation and maintenance of…”
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A glia-enriched stem cell 3D model of the human brain mimics the glial-immune neurodegenerative phenotypes of multiple sclerosis
Published in Cell reports. Medicine (20-08-2024)“…The role of central nervous system (CNS) glia in sustaining self-autonomous inflammation and driving clinical progression in multiple sclerosis (MS) is gaining…”
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Subventricular zone neural progenitors reverse TNF-alpha effects in cortical neurons
Published in Stem cell research & therapy (07-09-2015)“…Tumor necrosis factor alpha (TNFα) plays a physiological role in controlling synaptic transmission and plasticity in the healthy central nervous system by…”
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Role of endogenous neural precursor cells in demyelination and remyelination after cuprizone-induced injury
Published in Journal of neuroimmunology (01-01-2014)Get full text
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