Search Results - "Buttgereit, Thomas"

The 70th anniversary of glucocorticoids in rheumatic diseases: the second youth of an old friend by Palmowski, Yannick, Buttgereit, Thomas, Buttgereit, Frank

“…Abstract Seventy years ago, the first administration of cortisone in a patient with RA marked a milestone in the treatment of inflammatory diseases. However,…”
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Inhibition of Complex I of the Respiratory Chain, but Not Complex III, Attenuates Degranulation and Cytokine Secretion in Human Skin Mast Cells by Buttgereit, Thomas, Pfeiffenberger, Moritz, Frischbutter, Stefan, Krauß, Pierre-Louis, Chen, Yuling, Maurer, Marcus, Buttgereit, Frank, Gaber, Timo

“…The mechanisms of mast cell (MC) degranulation and MC-driven skin symptoms are well-described. In contrast, data about the role of mitochondrial respiration…”
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The real life experience goes on: update after 4 years on the first cohort treated with lanadelumab at our center by Buttgereit, Thomas, Vera Ayala, Carolina, Aykanat, Seda, Weller, Karsten, Gutsche, Annika, Maurer, Marcus, Magerl, Markus

“…Lanadelumab is a first-line long-term prophylaxis (LTP) in hereditary angioedema (HAE). Real-life data on its long-term efficacy and safety are limited. It is…”
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Production of IL-6 and Phagocytosis Are the Most Resilient Immune Functions in Metabolically Compromised Human Monocytes by Krauss, Pierre-Louis, Pfeiffenberger, Moritz, Damerau, Alexandra, Buttgereit, Thomas, Chen, Yuling, Gaber, Timo, Buttgereit, Frank

“…At sites of inflammation, monocytes carry out specific immune functions while facing challenging metabolic restrictions. Here, we investigated the potential of…”
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Patient-physician interactions in hereditary angioedema-Key learnings from the coronavirus disease 2019 pandemic by Maurer, Marcus, Buttgereit, Thomas, Magerl, Markus, Schön, Kathrin, Balla, Zsusanna, Farkas, Henriette

“…The coronavirus disease pandemic and its containing measures have caused concerns for patients with hereditary angioedema (HAE) and their treating physicians…”
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Age-related increase of mitochondrial content in human memory CD4+ T cells contributes to ROS-mediated increased expression of proinflammatory cytokines by Chen, Yuling, Ye, Yuanchun, Krauß, Pierre-Louis, Löwe, Pelle, Pfeiffenberger, Moritz, Damerau, Alexandra, Ehlers, Lisa, Buttgereit, Thomas, Hoff, Paula, Buttgereit, Frank, Gaber, Timo

“…Cellular metabolism modulates effector functions in human CD4 + T (Th) cells by providing energy and building blocks. Conversely, cellular metabolic responses…”
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Sensitivity to change and minimal clinically important difference of the angioedema control test by Fijen, Lauré M, Vera, Carolina, Buttgereit, Thomas, Bonnekoh, Hanna, Maurer, Marcus, Magerl, Markus, Weller, Karsten

“…The Angioedema Control Test (AECT) is a patient-reported outcome measure developed and validated for the assessment of disease control in patients with…”
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Lanadelumab Efficacy, Safety, and Injection Interval Extension in HAE: A Real-Life Study by Buttgereit, Thomas, Vera, Carolina, Weller, Karsten, Gutsche, Annika, Grekowitz, Eva Maria, Aykanat, Seda, Wahn, Volker, Krüger, Renate, Maurer, Marcus, Magerl, Markus

“…Lanadelumab has been available in Germany for the prophylactic treatment of hereditary angioedema since February 2019. To investigate real-life treatment…”
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The Diagnostic Workup in Chronic Spontaneous Urticaria—What to Test and Why by Metz, Martin, Altrichter, Sabine, Buttgereit, Thomas, Fluhr, Joachim W., Fok, Jie Shen, Hawro, Tomasz, Jiao, Qingqing, Kolkhir, Pavel, Krause, Karoline, Magerl, Markus, Pyatilova, Polina, Siebenhaar, Frank, Su, Huichun, Terhorst-Molawi, Dorothea, Weller, Karsten, Xiang, Yi-Kui, Maurer, Marcus

“…In chronic spontaneous urticaria (CSU), the guidelines recommend very limited diagnostic procedures during the routine workup, although additional…”
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Baricitinib rapidly and sustainably relieves a patient from chronic pruritus of unknown origin refractory to dupilumab by Buttgereit, Thomas, Grekowitz, Eva Maria, Metz, Martin

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Case report: Recurrent angioedema: Diagnosing the rare and the frequent by Buttgereit, Thomas, Fijen, Lauré M, Vera, Carolina, Bergmann, Karl-Christian, Maurer, Marcus, Magerl, Markus

“…Hereditary angiodema with normal C1 inhibitor and unknown mutation (HAE-nC1INH-UNK), an exceedingly rare subtype of HAE, appears to be often diagnosed in…”
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SIGLEC1 enables straightforward assessment of type I interferon activity in idiopathic inflammatory myopathies by Graf, Manuel, von Stuckrad, Sae Lim, Uruha, Akinori, Klotsche, Jens, Zorn-Pauly, Lydia, Unterwalder, Nadine, Buttgereit, Thomas, Krusche, Martin, Meisel, Christian, Burmester, Gerd R, Hiepe, Falk, Biesen, Robert, Kallinich, Tilmann, Stenzel, Werner, Schneider, Udo, Rose, Thomas

“…ObjectiveTo evaluate sialic acid binding Ig-like lectin 1 (SIGLEC1) expression on monocytes by flow cytometry as a type I interferon biomarker in idiopathic…”
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Urtikaria und Angioödeme: Was ist bei wem diagnostisch und therapeutisch zu tun? by Buttgereit, Thomas

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The 7-day recall period version of the Urticaria Control Test—UCT7 by Buttgereit, Thomas, Salameh, Pascale, Sydorenko, Olga, Zuberbier, Torsten, Metz, Martin, Weller, Karsten, Maurer, Marcus

“…The Urticaria Control Test (UCT) is a well-established, very easy to use and calculate 4-item patient-reported outcome measure to assess chronic urticaria…”
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Urticaria Control Test real‐world performance: A post‐hoc analysis by Salameh, Pascale, Gutsche, Annika, Aulenbacher, Felix, Buttgereit, Thomas, Weller, Karsten, Siebenhaar, Frank, Maurer, Marcus

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Response to “Clinical applicability of the Urticaria control test in patients with chronic urticaria: Further evidence from 622 adult and pediatric patients with different disease subtypes” by Gutsche, Annika, Salameh, Pascale, Aulenbacher, Felix, Buttgereit, Thomas, Weller, Karsten, Siebenhaar, Frank, Maurer, Marcus

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Idiopathic mast cell activation syndrome is more often suspected than diagnosed—A prospective real‐life study by Buttgereit, Thomas, Gu, Sophie, Carneiro‐Leão, Leonor, Gutsche, Annika, Maurer, Marcus, Siebenhaar, Frank

“…Background Idiopathic mast cell activation syndrome (MCAS) is characterized by three diagnostic criteria: (1) episodic mast cell (MC)‐driven signs/symptoms of…”
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How to Treat Patients with Chronic Spontaneous Urticaria with Omalizumab: Questions and Answers by Türk, Murat, Carneiro-Leão, Leonor, Kolkhir, Pavel, Bonnekoh, Hanna, Buttgereit, Thomas, Maurer, Marcus

“…Omalizumab is an effective treatment for patients with chronic spontaneous urticaria (CSU). In routine clinical practice, physicians often face complex cases…”
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Significant response to berotralstat in 3 patients with hereditary angioedema of unknown origin by Buttgereit, Thomas, Nicola, Stefania, Vera, Carolina, Brussino, Luisa, Maurer, Marcus, Magerl, Markus

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Applicability of trials in rheumatoid arthritis and osteoarthritis: A systematic review and meta-analysis of trial populations showing adequate proportion of women, but underrepresentation of elderly people by Palmowski, Andriko, Buttgereit, Thomas, Palmowski, Yannick, Nielsen, Sabrina M, Boers, Maarten, Christensen, Robin, Buttgereit, Frank

“…To evaluate whether elderly people and women are adequately represented in randomized controlled trials (RCT) in rheumatoid arthritis (RA) and osteoarthritis…”
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