Search Results - "Butterworth, R"

Review article: the design of clinical trials in hepatic encephalopathy – an International Society for Hepatic Encephalopathy and Nitrogen Metabolism (ISHEN) consensus statement by Bajaj, J. S., Cordoba, J., Mullen, K. D., Amodio, P., Shawcross, D. L., Butterworth, R. F., Morgan, M. Y.

“…Aliment Pharmacol Ther 2011; 33: 739–747 Summary Background  The clinical classification of hepatic encephalopathy is largely subjective, which has led to…”
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Update of Cell Damage Mechanisms in Thiamine Deficiency: Focus on Oxidative Stress, Excitotoxicity and Inflammation by Hazell, Alan S., Butterworth, Roger F.

“…Thiamine deficiency (TD) is a well-established model of Wernicke's encephalopathy. Although the neurologic dysfunction and brain damage resulting from the…”
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Parents' experiences of being in the Solihull Approach parenting group, 'Understanding Your Child's Behaviour': an interpretative phenomenological analysis by Vella, L. R., Butterworth, R. E., Johnson, R., Urquhart Law, G.

“…Background Empirical evidence suggests that the Solihull Approach parenting group, ‘Understanding Your Child's Behaviour’ (UYCB), can improve child behaviour…”
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Investigation of variant Creutzfeldt-Jakob disease and other human prion diseases with tonsil biopsy samples by Hill, AF, Butterworth, RJ, Joiner, S, Jackson, G, Rossor, MN, Thomas, DJ, Frosh, A, Tolley, N, Bell, JE, Spencer, M, King, A, Al-Sarraj, S, Ironside, JW, Lantos, PL, Collinge, J

“…Prion diseases are associated with the accumulation of an abnormal isoformof cellular prion protein (PrPSc), which is the principal constituent of prions…”
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Effects of hyperammonaemia on brain function by Butterworth, R. F.

“…Neuropsychiatric symptoms of hyperammonaemia include alterations of mood and personality, cognitive impairment, ataxia, convulsions and coma. The nature and…”
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Manganese deposition in basal ganglia structures results from both portal-systemic shunting and liver dysfunction by Rose, Christopher, Butterworth, Roger F., Zayed, Joseph, Normandin, Louise, Todd, Kathryn, Michalak, Adrianna, Spahr, Laurent, Huet, Pierre–Michel, Pomier–Layrargues, Gilles

“…Background & Aims: Manganese (Mn) deposition could be responsible for the T 1-weighted magnetic resonance signal hyperintensities observed in cirrhotic…”
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Neurobiology of ammonia by Felipo, Vicente, Butterworth, Roger F

“…Hyperammonemia resulting from inherited urea cycle enzyme deficiencies or liver failure results in severe central nervous system dysfunction including brain…”
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Determinants of clinical effectiveness and significant neurological diagnoses in an urgent brain cancer referral pathway in the United Kingdom by Webb, A.J.S, Butterworth, R.J

“…Highlights • Review of referrals and diagnoses from a UK secondary-care cancer referral pathway. • 31/105 patients received significant diagnoses, including 10…”
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Metformin-induced deafness in mitochondrial disease by Brady, S, Quagbeheur, G, Diot, A, Dombi, E, Hofer, M, Parry, A, Butterworth, R, Poulton, J

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Platelet size: measurement, physiology and vascular disease by Bath, P M, Butterworth, R J

“…Platelet volume is a marker of platelet function and activation. It is readily measured as mean platelet volume (MPV) by clinical haematology analysers using…”
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Neuroactive amino acids and glutamate (NMDA) receptors in frontal cortex of rats with experimental acute liver failure by Michalak, A, Rose, C, Butterworth, J, Butterworth, R F

“…It has been proposed that alterations of excitatory and inhibitory amino acids play a role in the pathogenesis of hepatic encephalopathy in acute liver…”
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Indomethacin improves locomotor deficit and reduces brain concentrations of neuroinhibitory steroids in rats following portacaval anastomosis by Ahboucha, S., Jiang, W., Chatauret, N., Mamer, O., Baker, G. B., Butterworth, R. F.

“…Hepatic encephalopathy (HE) is a neuropsychiatric complication of both acute and chronic liver failure characterized by progressive neuronal inhibition. Some…”
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Complications of cirrhosis III. Hepatic encephalopathy by Butterworth, Roger F.

“…Hepatic encephalopathy (HE) is a major neuropsychiatric complication of cirrhosis. HE develops slowly in cirrhotic patients, starting with altered sleep…”
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The Technology of Waste, Biofuels and Global Warming in Viable Closed Loop, Sustainable Operations by Butterworth, William R.

“…This research set out to explore and develop a route relating the recycling of urban and industrial wastes to land to produce agricultural crops with energy…”
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Increased blood manganese in cirrhotic patients: Relationship to pallidal magnetic resonance signal hyperintensity and neurological symptoms by Spahr, L, Butterworth, R F, Fontaine, S, Bui, L, Therrien, G, Milette, P C, Lebrun, L H, Zayed, J, Leblanc, A, Pomier‐Layrargues, G

“…Increasing evidence suggests that manganese deposition is responsible for the T1‐weighted magnetic resonance imaging (MRI) signal hyperintensity consistently…”
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Mild hypothermia delays the onset of coma and prevents brain edema and extracellular brain glutamate accumulation in rats with acute liver failure by Rose, Christopher, Michalak, Adrianna, Pannunzio, Marc, Chatauret, Nicolas, Rambaldi, Andrea, Butterworth, Roger F.

“…Mild hypothermia is effective in the prevention of brain edema associated with cerebral ischemia and traumatic brain injury. Brain edema is also a serious…”
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Decreased glutamate transporter ( GLT-1) expression in frontal cortex of rats with acute liver failure by Knecht, K, Michalak, A, Rose, C, Rothstein, J.D, Butterworth, R.F

“…It has been suggested that reduced astrocytic uptake of neuronally released glutamate contributes to the pathogenesis of hepatic encephalopathy in acute liver…”
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Ammonia and hepatic encephalopathy : The more things change, the more they remain the same by SHAWCROSS, D. L, OLDE DAMINK, S. W. M, BUTTERWORTH, R. F, JALAN, R

“…Ammonia is thought to be central in the pathogenesis of hepatic encephalopathy and has been of importance to generations dating back to the early Egyptians…”
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Dehydroepiandrosterone sulphate improves cholestasis‐associated fatigue in bile duct ligated rats by Butterworth, R. F., Lalonde, R., Power, C., Baker, G. B., Gamrani, H., Ahboucha, S.

“…:  Fatigue is a common debilitating symptom in patients with primary biliary cirrhosis (PBC). The mechanism of fatigue is still poorly understood. However, it…”
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L‐Ornithine‐L‐aspartate lowers plasma and cerebrospinal fluid ammonia and prevents brain edema in rats with acute liver failure by Rose, Christopher, Michalak, Adrianna, Rao, K. V., Quack, Günter, Kircheis, Gerald, Butterworth, Roger F.

“…Brain edema sufficient to cause intracranial hypertension and brain herniation remains a major cause of mortality in acute liver failure (ALF). Studies in…”
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