Search Results - "Buttari, Brigitta"

An Overview of Nrf2 Signaling Pathway and Its Role in Inflammation by Saha, Sarmistha, Buttari, Brigitta, Panieri, Emiliano, Profumo, Elisabetta, Saso, Luciano

“…Inflammation is a key driver in many pathological conditions such as allergy, cancer, Alzheimer's disease, and many others, and the current state of available…”
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A Perspective on Nrf2 Signaling Pathway for Neuroinflammation: A Potential Therapeutic Target in Alzheimer's and Parkinson's Diseases by Saha, Sarmistha, Buttari, Brigitta, Profumo, Elisabetta, Tucci, Paolo, Saso, Luciano

“…Neuroinflammation plays a pivotal role in Alzheimer's disease (AD) and Parkinson's disease (PD), the leading causes of dementia. These neurological disorders…”
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The Nrf2 Pathway in Ischemic Stroke: A Review by Farina, Marcelo, Vieira, Leonardo Eugênio, Buttari, Brigitta, Profumo, Elisabetta, Saso, Luciano

“…Ischemic stroke, characterized by the sudden loss of blood flow in specific area(s) of the brain, is the leading cause of permanent disability and is among the…”
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Crosstalk between Red Blood Cells and the Immune System and Its Impact on Atherosclerosis by Buttari, Brigitta, Riganò, Rachele, Profumo, Elisabetta

“…Atherosclerosis is a chronic multifactorial disease of the arterial wall characterized by inflammation, oxidative stress, and immune system activation…”
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An Overview of NRF2-Activating Compounds Bearing α,β-Unsaturated Moiety and Their Antioxidant Effects by Egbujor, Melford Chuka, Buttari, Brigitta, Profumo, Elisabetta, Telkoparan-Akillilar, Pelin, Saso, Luciano

“…The surge of scientific interest in the discovery of Nuclear Factor Erythroid 2 (NFE2)-Related Factor 2 (NRF2)-activating molecules underscores the importance…”
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Propranolol Promotes Monocyte-to-Macrophage Differentiation and Enhances Macrophage Anti-Inflammatory and Antioxidant Activities by NRF2 Activation by Maccari, Sonia, Profumo, Elisabetta, Saso, Luciano, Marano, Giuseppe, Buttari, Brigitta

“…Adrenergic pathways represent the main channel of communication between the nervous system and the immune system. During inflammation, blood monocytes migrate…”
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Editorial: Modulation of oxidative stress and inflammation via the NRF2 signaling pathway by Saha, Sarmistha, Buttari, Brigitta, Saso, Luciano

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A Pivotal Role of Nrf2 in Neurodegenerative Disorders: A New Way for Therapeutic Strategies by Suzen, Sibel, Tucci, Paolo, Profumo, Elisabetta, Buttari, Brigitta, Saso, Luciano

“…Clinical and preclinical research indicates that neurodegenerative diseases are characterized by excess levels of oxidative stress (OS) biomarkers and by lower…”
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Regulatory Role of Nrf2 Signaling Pathway in Wound Healing Process by Süntar, Ipek, Çetinkaya, Sümeyra, Panieri, Emiliano, Saha, Sarmistha, Buttari, Brigitta, Profumo, Elisabetta, Saso, Luciano

“…Wound healing involves a series of cellular events in damaged cells and tissues initiated with hemostasis and finally culminating with the formation of a…”
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Pharmacological Protection against Ischemia-Reperfusion Injury by Regulating the Nrf2-Keap1-ARE Signaling Pathway by Ucar, Bercis Imge, Ucar, Gulberk, Saha, Sarmistha, Buttari, Brigitta, Profumo, Elisabetta, Saso, Luciano

“…Ischemia/reperfusion (I/R) injury is associated with substantial clinical implications, including a wide range of organs such as the brain, kidneys, lungs,…”
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The Double-Edged Sword of Erythrocytes in Health and Disease via Their Adhesiveness by Asaro, Robert J, Profumo, Elisabetta, Buttari, Brigitta, Cabrales, Pedro

“…Their widespread presence throughout the vasculature, coupled with their reactivity, and thereby to their potential to release reactive oxidative species, or…”
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NRF2: A crucial regulator for mitochondrial metabolic shift and prostate cancer progression by Buttari, Brigitta, Arese, Marzia, Oberley-Deegan, Rebecca E., Saso, Luciano, Chatterjee, Arpita

“…Metabolic alterations are a common survival mechanism for prostate cancer progression and therapy resistance. Oxidative stress in the cellular and tumor…”
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Neuropeptide Y Promotes Human M2 Macrophage Polarization and Enhances p62/SQSTM1-Dependent Autophagy and NRF2 Activation by Profumo, Elisabetta, Maggi, Elisa, Arese, Marzia, Di Cristofano, Claudio, Salvati, Bruno, Saso, Luciano, Businaro, Rita, Buttari, Brigitta

“…Neuropeptide Y (NPY) is an abundantly expressed peptide capable of modulating innate and adaptive immune responses and regulating chemotaxis and cytokine…”
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Pleiotropic effects of statins in atherosclerotic disease: focus on the antioxidant activity of atorvastatin by Profumo, Elisabetta, Buttari, Brigitta, Saso, Luciano, Rigano, Rachele

“…Cardiovascular diseases, which are the leading cause of mortality in the Western World, are closely associated with atherosclerosis development…”
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Oxidative Stress in Mucopolysaccharidoses: Pharmacological Implications by Pierzynowska, Karolina, Gaffke, Lidia, Cyske, Zuzanna, Węgrzyn, Grzegorz, Buttari, Brigitta, Profumo, Elisabetta, Saso, Luciano

“…Although mucopolysaccharidoses (MPS) are caused by mutations in genes coding for enzymes responsible for degradation of glycosaminoglycans, storage of these…”
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Trends of overweight, obesity and anthropometric measurements among the adult population in Italy: The CUORE Project health examination surveys 1998, 2008, and 2018 by Donfrancesco, Chiara, Profumo, Elisabetta, Lo Noce, Cinzia, Minutoli, Daniela, Di Lonardo, Anna, Buttari, Brigitta, Vespasiano, Francesca, Vannucchi, Serena, Galletti, Ferruccio, Onder, Graziano, Colivicchi, Furio, Galeone, Daniela, Bellisario, Paolo, Palmieri, Luigi

“…Obesity is associated with an increased risk of noncommunicable diseases, such as diabetes, coronary heart disease, stroke, cancers, and conditions, including…”
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Antioxidant Cardioprotection against Reperfusion Injury: Potential Therapeutic Roles of Resveratrol and Quercetin by Rodrigo, Ramón, Retamal, Catalina, Schupper, Denisse, Vergara-Hernández, Diego, Saha, Sarmistha, Profumo, Elisabetta, Buttari, Brigitta, Saso, Luciano

“…Ischemia-reperfusion myocardial damage is a paradoxical tissue injury occurring during percutaneous coronary intervention (PCI) in acute myocardial infarction…”
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Phenotypical and functional abnormalities of circulating neutrophils in patients with β-thalassemia by Buttari, Brigitta, Profumo, Elisabetta, Caprari, Patrizia, Massimi, Sara, Sorrentino, Francesco, Maffei, Laura, Gabbianelli, Marco, Riganò, Rachele

“…β-Thalassemia is an inherited single gene disorder related to reduced synthesis of the β-globin chain of hemoglobin. Patients with β-thalassemia present…”
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Alkaloids as Natural NRF2 Inhibitors: Chemoprevention and Cytotoxic Action in Cancer by Gjorgieva Ackova, Darinka, Maksimova, Viktorija, Smilkov, Katarina, Buttari, Brigitta, Arese, Marzia, Saso, Luciano

“…Being a controller of cytoprotective actions, inflammation, and mitochondrial function through participating in the regulation of multiple genes in response to…”
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Oxidative Stress and Cancer Heterogeneity Orchestrate NRF2 Roles Relevant for Therapy Response by Gall Trošelj, Koraljka, Tomljanović, Marko, Jaganjac, Morana, Matijević Glavan, Tanja, Čipak Gašparović, Ana, Milković, Lidija, Borović Šunjić, Suzana, Buttari, Brigitta, Profumo, Elisabetta, Saha, Sarmistha, Saso, Luciano, Žarković, Neven

“…Oxidative stress and its end-products, such as 4-hydroxynonenal (HNE), initiate activation of the Nuclear Factor Erythroid 2-Related Factor 2 (NRF2)/Kelch Like…”
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