Search Results - "Buttó, Stefano"
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New insights into pathogenesis point to HIV-1 Tat as a key vaccine target
Published in Archives of virology (01-11-2021)“…Despite over 30 years of enormous effort and progress in the field, no preventative and/or therapeutic vaccines against human immunodeficiency virus (HIV) are…”
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HIV virology and pathogenetic mechanisms of infection: a brief overview
Published in Annali dell'Istituto superiore di sanità (01-03-2010)“…Studies on HIV virology and pathogenesis address the complex mechanisms that result in the HIV infection of the cell and destruction of the immune system…”
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Characterization of HIV type 1 genetic diversity among South African participants enrolled in the AIDS Vaccine Integrated Project (AVIP) study
Published in AIDS research and human retroviruses (01-06-2010)“…The genetic diversity of HIV-1 strains circulating among HIV-1-infected South Africans was investigated in a cohort of 420 individuals enrolled as part of the…”
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HIV therapeutic vaccines aimed at intensifying combination antiretroviral therapy
Published in Expert review of vaccines (02-01-2020)“…: Although successful at suppressing HIV replication, combination antiretroviral therapy (cART) only partially restores immune functions and fails to reduce…”
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Analysis of HIV‐1 integrase genotypes and polymorphisms among integrase inhibitors‐based antiretroviral treatment naïve patients in South Sudan
Published in Journal of medical virology (01-07-2022)“…HIV‐1 genetic diversity and drug resistance mutations remain public health challenges especially in regions where treatment is limited. The aim of this study…”
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Anti-Tat Immunity in HIV-1 Infection: Effects of Naturally Occurring and Vaccine-Induced Antibodies Against Tat on the Course of the Disease
Published in Vaccines (Basel) (26-08-2019)“…HIV-1 Tat is an essential protein in the virus life cycle, which is required for virus gene expression and replication. Most Tat that is produced during…”
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"cART intensification by the HIV-1 Tat B clade vaccine: progress to phase III efficacy studies"
Published in Expert review of vaccines (01-02-2018)“…In spite of its success at suppressing HIV replication, combination antiretroviral therapy (cART) only partially reduces immune dysregulation and loss of…”
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Health inequalities: a Research Positioning Exercise at the National Institute of Health, Italy
Published in European journal of public health (01-10-2019)“…Abstract Background The Italian National Institute of Health (Istituto Superiore di Sanità, ISS) considers health inequalities (HI) an important area of…”
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Development of a novel AIDS vaccine: the HIV-1 transactivator of transcription protein vaccine
Published in Expert opinion on biological therapy (2015)“…Classical approaches aimed at targeting the HIV-1 envelope as well as other structural viral proteins have largely failed. The HIV-1 transactivator of…”
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HIV-Tat immunization induces cross-clade neutralizing antibodies and CD4(+) T cell increases in antiretroviral-treated South African volunteers: a randomized phase II clinical trial
Published in Retrovirology (09-06-2016)“…Although combined antiretroviral therapy (cART) has saved millions of lives, it is incapable of full immune reconstitution and virus eradication. The…”
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The Presence of Anti-Tat Antibodies Is Predictive of Long-Term Nonprogression to AIDS or Severe Immunodeficiency: Findings in a Cohort of HIV-1 Seroconverters
Published in The Journal of infectious diseases (15-04-2005)“…The human immunodeficiency virus (HIV) type 1 Tat protein plays a key role in the life cycle of the virus and in pathogenesis and is highly conserved among HIV…”
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Building up a collaborative network for the surveillance of HIV genetic diversity in Italy. A pilot study
Published in Annali dell'Istituto superiore di sanità (01-12-2015)“…Prevalence of infection with HIV-1 non-B subtypes in Italy has been reported to raise, due to increased migration flows and travels. HIV-1 variants show…”
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Correlates of infection and molecular characterization of blood-borne HIV, HCV, and HBV infections in HIV-1 infected inmates in Italy: An observational cross-sectional study
Published in Medicine (Baltimore) (01-11-2016)“…Coinfection of blood-borne hepatitis B and hepatitis C viruses (HBV and HCV, respectively) in human immunodeficiency virus type 1 (HIV-1)-positive individuals…”
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Molecular characterization of HIV-1 subtype C gp-120 regions potentially involved in virus adaptive mechanisms
Published in PloS one (01-04-2014)“…The role of variable regions of HIV-1 gp120 in immune escape of HIV has been investigated. However, there is scant information on how conserved gp120 regions…”
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Laboratory diagnostics for HIV infection
Published in Annali dell'Istituto superiore di sanità (01-03-2010)“…Laboratory diagnosis of human immunodeficiency virus (HIV) infection is fundamental for detecting and monitoring infection. Many diagnostic tools are available…”
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Candidate HIV-1 Tat vaccine development : from basic science to clinical trials
Published in AIDS (London) (28-11-2006)Get full text
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Complex associates of plasmid DNA and a novel class of block copolymers with PEG and cationic segments as new vectors for gene delivery
Published in Journal of biomaterials science. Polymer ed. (01-01-2001)“…Cationic block copolymers, consisting of a poly(ethylene glycol) block and a block deriving from the poly(dimethylamino)ethyl methacrylate were prepared via a…”
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Identification of recent HIV infections and of factors associated with virus acquisition among pregnant women in 2004 and 2006 in Swaziland
Published in Journal of clinical virology (01-07-2010)“…Abstract Background HIV continues to spread at high rates in sub-Saharan Africa. In particular, Swaziland is one of the countries most affected by the HIV/AIDS…”
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The epidemic of HIV infection and AIDS, promotion of testing, and innovative strategies
Published in Annali dell'Istituto superiore di sanità (01-03-2010)“…In Europe, the incidence of new diagnoses of HIV infection in 2008 was 86.7 cases per one million population, and most cases were attributable to sexual…”
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A multiplex calibrated real-time PCR assay for quantitation of DNA of EBV-1 and 2
Published in Journal of virological methods (01-12-2011)“…► A new molecular assay is described for reliable quantitation of EBV DNA in clinical samples. ► The system quantify both EBV subtypes (European/Asian and…”
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