Search Results - "Buttó, Ludovica"
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Dysbiosis in intestinal inflammation: Cause or consequence
Published in International journal of medical microbiology (01-08-2016)“…Abstract The intestinal microbiota encompasses hundreds of bacterial species that constitute a relatively stable ecosystem. Alteration in the microbiota…”
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Exposure of Bifidobacterium longum subsp. infantis to Milk Oligosaccharides Increases Adhesion to Epithelial Cells and Induces a Substantial Transcriptional Response
Published in PloS one (21-06-2013)“…In this study, we tested the hypothesis that milk oligosaccharides may contribute not only to selective growth of bifidobacteria, but also to their specific…”
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Functional relevance of microbiome signatures: The correlation era requires tools for consolidation
Published in Journal of allergy and clinical immunology (01-04-2017)“…Compelling research over the past decade identified a fundamental role of the intestinal microbiome on human health. Compositional and functional changes of…”
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Neutralization of IL-1α ameliorates Crohn’s disease-like ileitis by functional alterations of the gut microbiome
Published in Proceedings of the National Academy of Sciences - PNAS (26-12-2019)“…Crohn’s disease and ulcerative colitis are chronic and progressive inflammatory bowel diseases (IBDs) that are attributed to dysregulated interactions between…”
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Mechanisms of Microbe-Host Interaction in Crohn's Disease: Dysbiosis vs. Pathobiont Selection
Published in Frontiers in immunology (19-11-2015)“…Crohn's disease (CD) is a systemic chronic inflammatory condition mainly characterized by discontinuous transmural pathology of the gastrointestinal tract and…”
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Mechanism of protection of transepithelial barrier function by Lactobacillus salivarius: strain dependence and attenuation by bacteriocin production
Published in American journal of physiology: Gastrointestinal and liver physiology (01-11-2012)“…Enhanced barrier function is one mechanism whereby commensals and probiotic bacteria limit translocation of foreign antigens or pathogens in the gut. However,…”
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Replacing Animal Protein with Soy-Pea Protein in an "American Diet" Controls Murine Crohn Disease-Like Ileitis Regardless of Firmicutes: Bacteroidetes Ratio
Published in The Journal of nutrition (01-03-2021)“…The current nutritional composition of the "American diet" (AD; also known as Western diet) has been linked to the increasing incidence of chronic diseases,…”
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Dysbiosis in Crohn's disease - Joint action of stochastic injuries and focal inflammation in the gut
Published in Gut microbes (02-01-2017)“…Gut homeostasis involves interrelated biological networks that include the immune system, specialized cells of the epithelium, such as Paneth and goblet cells,…”
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Intestinal Stem Cell Niche Defects Result in Impaired 3D Organoid Formation in Mouse Models of Crohn's Disease-like Ileitis
Published in Stem cell reports (11-08-2020)“…Intestinal epithelial barrier dysfunction is a risk factor in the pathogenesis of Crohn’s disease (CD); however, no corrective FDA-approved therapies exist. We…”
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Death Receptor 3 Signaling Controls the Balance between Regulatory and Effector Lymphocytes in SAMP1/YitFc Mice with Crohn's Disease-Like Ileitis
Published in Frontiers in immunology (01-03-2018)“…Death receptor 3 (DR3), a member of the tumor necrosis factor receptor (TNFR) superfamily, has been implicated in regulating T-helper type-1 (T 1), type-2 (T…”
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Molecular dialogue between the human gut microbiota and the host: a Lactobacillus and Bifidobacterium perspective
Published in Cellular and molecular life sciences : CMLS (01-01-2014)“…The human gut represents a highly complex ecosystem, which is densely colonized by a myriad of microorganisms that influence the physiology, immune function…”
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Macrophage cytokine responses to commensal Gram-positive Lactobacillus salivarius strains are TLR2-independent and Myd88-dependent
Published in Scientific reports (15-03-2021)“…The mechanisms through which cells of the host innate immune system distinguish commensal bacteria from pathogens are currently unclear. Toll-like receptors…”
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Human Gut Microbiome Transplantation in Ileitis Prone Mice: A Tool for the Functional Characterization of the Microbiota in Inflammatory Bowel Disease Patients
Published in Inflammatory bowel diseases (11-02-2020)“…Abstract Background Inflammatory bowel disease (IBD) is a lifelong digestive disease characterized by periods of severe inflammation and remission. To our…”
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Influence of Adhesion and Bacteriocin Production by Lactobacillus salivarius on the Intestinal Epithelial Cell Transcriptional Response
Published in Applied and Environmental Microbiology (01-08-2012)“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Death-Domain-Receptor 3 Deletion Normalizes Inflammatory Gene Expression and Prevents Ileitis in Experimental Crohn's Disease
Published in Inflammatory bowel diseases (01-01-2019)“…Abstract Background TNF-like cytokine 1A (TL1A) and its functional receptor, death-domain-receptor-3 (DR3), are multifunctional mediators of effector and…”
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Prebiotic supplementation in frail older people affects specific gut microbiota taxa but not global diversity
Published in Microbiome (13-03-2019)“…There are complex interactions between aging, frailty, diet, and the gut microbiota; modulation of the gut microbiota by diet could lead to healthier aging…”
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Interleukin 33 Triggers Early Eosinophil-Dependent Events Leading to Metaplasia in a Chronic Model of Gastritis-Prone Mice
Published in Gastroenterology (New York, N.Y. 1943) (01-01-2021)“…Interleukin (IL)33/IL1F11 is an important mediator for the development of type 2 T-helper cell (Th2)–driven inflammatory disorders and has also been implicated…”
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Candida tropicalis Infection Modulates the Gut Microbiome and Confers Enhanced Susceptibility to Colitis in Mice
Published in Cellular and molecular gastroenterology and hepatology (01-01-2022)“…We previously showed that abundance of Candida tropicalis is significantly greater in Crohn’s disease patients compared with first-degree relatives without…”
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