Search Results - "Butt, Haroon"

RNA virus interference via CRISPR/Cas13a system in plants by Aman, Rashid, Ali, Zahir, Butt, Haroon, Mahas, Ahmed, Aljedaani, Fatimah, Khan, Muhammad Zuhaib, Ding, Shouwei, Mahfouz, Magdy

“…CRISPR/Cas systems confer immunity against invading nucleic acids and phages in bacteria and archaea. CRISPR/Cas13a (known previously as C2c2) is a class 2…”
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Engineering plant architecture via CRISPR/Cas9-mediated alteration of strigolactone biosynthesis by Butt, Haroon, Jamil, Muhammad, Wang, Jian You, Al-Babili, Salim, Mahfouz, Magdy

“…Precision plant genome engineering holds much promise for targeted improvement of crop traits via unprecedented single-base level control over the genetic…”
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Synthetic directed evolution for targeted engineering of plant traits by Kababji, Ahad Moussa, Butt, Haroon, Mahfouz, Magdy

“…Improving crop traits requires genetic diversity, which allows breeders to select advantageous alleles of key genes. In species or loci that lack sufficient…”
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CRISPR directed evolution of the spliceosome for resistance to splicing inhibitors by Butt, Haroon, Eid, Ayman, Momin, Afaque A, Bazin, Jeremie, Crespi, Martin, Arold, Stefan T, Mahfouz, Magdy M

“…Increasing genetic diversity via directed evolution holds great promise to accelerate trait development and crop improvement. We developed a CRISPR/Cas-based…”
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Engineering RNA Virus Interference via the CRISPR/Cas13 Machinery in Arabidopsis by Aman, Rashid, Mahas, Ahmed, Butt, Haroon, Aljedaani, Fatimah, Mahfouz, Magdy

“…Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) systems are key immune mechanisms helping prokaryotic species…”
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Efficient CRISPR/Cas9-Mediated Genome Editing Using a Chimeric Single-Guide RNA Molecule by Butt, Haroon, Eid, Ayman, Ali, Zahir, Atia, Mohamed A M, Mokhtar, Morad M, Hassan, Norhan, Lee, Ciaran M, Bao, Gang, Mahfouz, Magdy M

“…The CRISPR/Cas9 system has been applied in diverse eukaryotic organisms for targeted mutagenesis. However, targeted gene editing is inefficient and requires…”
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Fusion of the Cas9 endonuclease and the VirD2 relaxase facilitates homology-directed repair for precise genome engineering in rice by Ali, Zahir, Shami, Ashwag, Sedeek, Khalid, Kamel, Radwa, Alhabsi, Abdulrahman, Tehseen, Muhammad, Hassan, Norhan, Butt, Haroon, Kababji, Ahad, Hamdan, Samir M., Mahfouz, Magdy M.

“…Precise genome editing by systems such as clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) requires…”
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Pre‐mRNA splicing repression triggers abiotic stress signaling in plants by Ling, Yu, Alshareef, Sahar, Butt, Haroon, Lozano‐Juste, Jorge, Li, Lixin, Galal, Aya A., Moustafa, Ahmed, Momin, Afaque A., Tashkandi, Manal, Richardson, Dale N., Fujii, Hiroaki, Arold, Stefan, Rodriguez, Pedro L., Duque, Paula, Mahfouz, Magdy M.

“…Summary Alternative splicing (AS) of precursor RNAs enhances transcriptome plasticity and proteome diversity in response to diverse growth and stress cues…”
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Retraction Note: PPP1, a plant-specific regulator of transcription controls Arabidopsis development and PIN expression by Benjamins, René, Barbez, Elke, Ortbauer, Martina, Terpstra, Inez, Lucyshyn, Doris, Moulinier-Anzola, Jeanette, Khan, Muhammad Asaf, Leitner, Johannes, Malenica, Nenad, Butt, Haroon, Korbei, Barbara, Scheres, Ben, Kleine-Vehn, Jürgen, Luschnig, Christian

“…Editor's Note: this Article has been retracted; the Retraction Note is available at https://doi.org/10.1038/s41598-021-87406-5 …”
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Putative Arabidopsis Transcriptional Adaptor Protein (PROPORZ1) is required to modulate histone acetylation in response to auxin by Anzola, Jeanette Moulinier, Sieberer, Tobias, Ortbauer, Martina, Butt, Haroon, Korbei, Barbara, Weinhofer, Isabelle, Müllner, Almuth Elise, Luschnig, Christian

“…Plant development is highly adaptable and controlled by a combination of various regulatory circuits that integrate internal and environmental cues. The…”
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Overlapping roles of spliceosomal components SF3B1 and PHF5A in rice splicing regulation by Butt, Haroon, Bazin, Jeremie, Alshareef, Sahar, Eid, Ayman, Benhamed, Moussa, Reddy, Anireddy S. N., Crespi, Martin, Mahfouz, Magdy M.

“…The SF3B complex, a multiprotein component of the U2 snRNP of the spliceosome, plays a crucial role in recognizing branch point sequence and facilitates…”
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The Rice Serine/Arginine Splicing Factor RS33 Regulates Pre-mRNA Splicing during Abiotic Stress Responses by Butt, Haroon, Bazin, Jeremie, Prasad, Kasavajhala V S K, Awad, Nourelislam, Crespi, Martin, Reddy, Anireddy S N, Mahfouz, Magdy M

“…Abiotic stresses profoundly affect plant growth and development and limit crop productivity. Pre-mRNA splicing is a major form of gene regulation that helps…”
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RETRACTED ARTICLE: PPP1, a plant-specific regulator of transcription controls Arabidopsis development and PIN expression by Benjamins, René, Barbez, Elke, Ortbauer, Martina, Terpstra, Inez, Lucyshyn, Doris, Moulinier-Anzola, Jeanette, Khan, Muhammad Asaf, Leitner, Johannes, Malenica, Nenad, Butt, Haroon, Korbei, Barbara, Scheres, Ben, Kleine-Vehn, Jürgen, Luschnig, Christian

“…Directional transport of auxin is essential for plant development, with PIN auxin transport proteins representing an integral part of the machinery that…”
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Herboxidiene triggers splicing repression and abiotic stress responses in plants by AlShareef, Sahar, Ling, Yu, Butt, Haroon, Mariappan, Kiruthiga G, Benhamed, Moussa, Mahfouz, Magdy M

“…Constitutive and alternative splicing of pre-mRNAs from multiexonic genes controls the diversity of the proteome; these precisely regulated processes also…”
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Crop bioengineering via gene editing: reshaping the future of agriculture by Atia, Mohamed, Jiang, Wenjun, Sedeek, Khalid, Butt, Haroon, Mahfouz, Magdy

“…Genome-editing technologies have revolutionized research in plant biology, with major implications for agriculture and worldwide food security, particularly in…”
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CRISPR-Based Directed Evolution for Crop Improvement by Butt, Haroon, Zaidi, Syed Shan-e-Ali, Hassan, Norhan, Mahfouz, Magdy

“…Directed evolution involves generating diverse sequence variants of a gene of interest to produce a desirable trait under selective pressure. CRISPR-Cas9…”
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SCR106 splicing factor modulates abiotic stress responses by maintaining RNA splicing in rice by Alhabsi, Abdulrahman, Butt, Haroon, Kirschner, Gwendolyn K, Blilou, Ikram, Mahfouz, Magdy M

“…Plants employ sophisticated molecular machinery to fine-tune their responses to growth, developmental, and stress cues. Gene expression influences plant…”
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Serine/Arginine-rich protein family of splicing regulators: New approaches to study splice isoform functions by Morton, Mitchell, AlTamimi, Nadia, Butt, Haroon, Reddy, Anireddy S.N., Mahfouz, Magdy

“…•Serine/arginine-rich (SR) proteins bind RNA and function in stress responses.•Conserved SR proteins modulate alternative splicing and other aspects of RNA…”
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Engineering herbicide resistance via prime editing in rice by Butt, Haroon, Rao, Gundra Sivakrishna, Sedeek, Khalid, Aman, Rashid, Kamel, Radwa, Mahfouz, Magdy

“…In plants, homology‐directed repair is inefficient, limiting our ability to make precise edits of the DNA sequence (Ali et al., 2020; Butt et al., 2017)…”
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Expression analysis of Arabidopsis XH/XS-domain proteins indicates overlapping and distinct functions for members of this gene family by Butt, Haroon, Graner, Sonja, Luschnig, Christian

“…RNA-directed DNA methylation (RdDM) is essential for de novo DNA methylation in higher plants, and recent reports established novel elements of this silencing…”
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