The PATRIC Bioinformatics Resource Center: expanding data and analysis capabilities

Abstract The PathoSystems Resource Integration Center (PATRIC) is the bacterial Bioinformatics Resource Center funded by the National Institute of Allergy and Infectious Diseases (https://www.patricbrc.org). PATRIC supports bioinformatic analyses of all bacteria with a special emphasis on pathogens,...

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Published in:	Nucleic acids research Vol. 48; no. D1; pp. D606 - D612
Main Authors:	Davis, James J, Wattam, Alice R, Aziz, Ramy K, Brettin, Thomas, Butler, Ralph, Butler, Rory M, Chlenski, Philippe, Conrad, Neal, Dickerman, Allan, Dietrich, Emily M, Gabbard, Joseph L, Gerdes, Svetlana, Guard, Andrew, Kenyon, Ronald W, Machi, Dustin, Mao, Chunhong, Murphy-Olson, Dan, Nguyen, Marcus, Nordberg, Eric K, Olsen, Gary J, Olson, Robert D, Overbeek, Jamie C, Overbeek, Ross, Parrello, Bruce, Pusch, Gordon D, Shukla, Maulik, Thomas, Chris, VanOeffelen, Margo, Vonstein, Veronika, Warren, Andrew S, Xia, Fangfang, Xie, Dawen, Yoo, Hyunseung, Stevens, Rick
Format:	Journal Article
Language:	English
Published:	England Oxford University Press 08-01-2020
Subjects:	Algorithms Animals Bacteria - genetics BASIC BIOLOGICAL SCIENCES Caenorhabditis elegans - genetics Chickens - genetics Computational Biology - methods Database Issue Databases, Genetic Drosophila melanogaster - genetics Host-Pathogen Interactions - genetics Humans Internet KNOWLEDGE MANAGEMENT AND PRESERVATION Macaca mulatta - genetics Metagenomics Mice National Institute of Allergy and Infectious Diseases (U.S.) Phenotype Phylogeny Rats Swine - genetics United States Zebrafish - genetics United States
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Summary:	Abstract The PathoSystems Resource Integration Center (PATRIC) is the bacterial Bioinformatics Resource Center funded by the National Institute of Allergy and Infectious Diseases (https://www.patricbrc.org). PATRIC supports bioinformatic analyses of all bacteria with a special emphasis on pathogens, offering a rich comparative analysis environment that provides users with access to over 250 000 uniformly annotated and publicly available genomes with curated metadata. PATRIC offers web-based visualization and comparative analysis tools, a private workspace in which users can analyze their own data in the context of the public collections, services that streamline complex bioinformatic workflows and command-line tools for bulk data analysis. Over the past several years, as genomic and other omics-related experiments have become more cost-effective and widespread, we have observed considerable growth in the usage of and demand for easy-to-use, publicly available bioinformatic tools and services. Here we report the recent updates to the PATRIC resource, including new web-based comparative analysis tools, eight new services and the release of a command-line interface to access, query and analyze data.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 AC02-06CH11357 USDOE National Institutes of Health (NIH) - National Institute of Allergy and Infectious Diseases (NIAID) U. S. Department of Health and Human Services
ISSN:	0305-1048 1362-4962
DOI:	10.1093/nar/gkz943