Search Results - "Butler, Rachel E"

Molecular basis for DarT ADP-ribosylation of a DNA base by Schuller, Marion, Butler, Rachel E., Ariza, Antonio, Tromans-Coia, Callum, Jankevicius, Gytis, Claridge, Tim D. W., Kendall, Sharon L., Goh, Shan, Stewart, Graham R., Ahel, Ivan

“…ADP-ribosyltransferases use NAD + to catalyse substrate ADP-ribosylation 1 , and thereby regulate cellular pathways or contribute to toxin-mediated…”
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Transposon libraries identify novel Mycobacterium bovis BCG genes involved in the dynamic interactions required for BCG to persist during in vivo passage in cattle by Mendum, Tom A, Chandran, Aneesh, Williams, Kerstin, Vordermeier, H Martin, Villarreal-Ramos, Bernardo, Wu, H, Singh, Albel, Smith, Alex A, Butler, Rachel E, Prasad, Aravind, Bharti, Neeraj, Banerjee, Ruma, Kasibhatla, Sunitha M, Bhatt, Apoorva, Stewart, Graham R, McFadden, Johnjoe

“…BCG is the most widely used vaccine of all time and remains the only licensed vaccine for use against tuberculosis in humans. BCG also protects other species…”
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The balance of apoptotic and necrotic cell death in Mycobacterium tuberculosis infected macrophages is not dependent on bacterial virulence by Butler, Rachel E, Brodin, Priscille, Jang, Jichan, Jang, Mi-Seon, Robertson, Brian D, Gicquel, Brigitte, Stewart, Graham R

“…An important mechanism of Mycobacterium tuberculosis pathogenesis is the ability to control cell death pathways in infected macrophages: apoptotic cell death…”
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Temporal genome-wide fitness analysis of Mycobacterium marinum during infection reveals the genetic requirement for virulence and survival in amoebae and microglial cells by Lefrançois, Louise H, Nitschke, Jahn, Wu, Huihai, Panis, Gaël, Prados, Julien, Butler, Rachel E, Mendum, Tom A, Hanna, Nabil, Stewart, Graham R, Soldati, Thierry

“…Tuberculosis remains the most pervasive infectious disease and the recent emergence of drug-resistant strains emphasizes the need for more efficient drug…”
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Identification of gene targets that potentiate the action of rifampicin on Mycobacterium bovis BCG by Chand, Pooja, Mendum, Tom A, Butler, Rachel E, Hingley-Wilson, Suzanne M, Stewart, Graham R

“…Tuberculosis (TB) caused by bacteria of the complex remains one of the most important infectious diseases of mankind. Rifampicin is a first line drug used in…”
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Applications of High-Throughput Clonogenic Survival Assays in High-LET Particle Microbeams by Georgantzoglou, Antonios, Merchant, Michael J, Jeynes, Jonathan C G, Mayhead, Natalie, Punia, Natasha, Butler, Rachel E, Jena, Rajesh

“…Charged particle therapy is increasingly becoming a valuable tool in cancer treatment, mainly due to the favorable interaction of particle radiation with…”
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Loss of phenotypic inheritance associated with ydcI mutation leads to increased frequency of small, slow persisters in Escherichia coli by Hingley-Wilson, Suzanne M., Ma, Nan, Hu, Yin, Casey, Rosalyn, Bramming, Anders, Curry, Richard J., Tang, Hongying Lilian, Wu, Huihai, Butler, Rachel E., Jacobs, William R., Rocco, Andrea, McFadden, Johnjoe

“…Whenever a genetically homogenous population of bacterial cells is exposed to antibiotics, a tiny fraction of cells survives the treatment, the phenomenon…”
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Mycobacterium bovis uses the ESX-1 Type VII secretion system to escape predation by the soil-dwelling amoeba Dictyostelium discoideum by Butler, Rachel E, Smith, Alex A., Mendum, Tom A., Chandran, Aneesh, Wu, Huihai, Lefrançois, Louise, Chambers, Mark, Soldati, Thierry, Stewart, Graham R

“…Mycobacterium bovis is the causative agent of bovine tuberculosis and the predominant cause of zoonotic tuberculosis in people. Bovine tuberculosis occurs in…”
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Susceptibility of Mycobacterium tuberculosis-infected host cells to phospho-MLKL driven necroptosis is dependent on cell type and presence of TNFα by Butler, Rachel E., Krishnan, Nitya, Garcia-Jimenez, Waldo, Francis, Robert, Martyn, Abbe, Mendum, Tom, Felemban, Shaza, Locker, Nicolas, Salguero, Francisco J., Robertson, Brian, Stewart, Graham R.

“…An important feature of Mycobacterium tuberculosis pathogenesis is the ability to control cell death in infected host cells, including inhibition of apoptosis…”
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ClgR regulation of chaperone and protease systems is essential for Mycobacterium tuberculosis parasitism of the macrophage by ESTORNINHO, Megan, SMITH, Hilde, THOLE, Jelle, HARDERS-WESTERVEEN, Jose, KIERZEK, Andrzej, BUTLER, Rachel E, NEYROLLES, Olivier, STEWART, Graham R

“…Chaperone and protease systems play essential roles in cellular homeostasis and have vital functions in controlling the abundance of specific cellular proteins…”
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Effective generation of reactive oxygen species in the mycobacterial phagosome requires K+ efflux from the bacterium by Butler, Rachel E, Cihlarova, Vera, Stewart, Graham R

“…Efficient killing of mycobacteria by host macrophages depends on a number of mechanisms including production of reactive oxygen species (ROS) by the phagosomal…”
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Effective generation of reactive oxygen species in the mycobacterial phagosome requires K+ efflux from the bacterium: Bacterial K+ efflux affects phagosomal ROS production by Butler, Rachel E., Cihlarova, Vera, Stewart, Graham R.

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Editor's note by Butler, Rachel E.

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Editor's note by Butler, Rachel E.

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Editor's note by Butler, Rachel E.

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Editor's note by Butler, Rachel E.

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Editor's note by Butler, Rachel E.

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Editor's note by Butler, Rachel E.

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Editor's note by Butler, Rachel E.

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Editor's note by Butler, Rachel E.

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