Search Results - "Butler, Margaret H."

Sumoylation Silences the Plasma Membrane Leak K + Channel K2P1 by Rajan, Sindhu, Plant, Leigh D., Rabin, Michael L., Butler, Margaret H., Goldstein, Steve A.N.

“…Reversible, covalent modification with small ubiquitin-related modifier proteins (SUMOs) is known to mediate nuclear import/export and activity of…”
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Tuba, a Novel Protein Containing Bin/Amphiphysin/Rvs and Dbl Homology Domains, Links Dynamin to Regulation of the Actin Cytoskeleton by Salazar, Marco A., Kwiatkowski, Adam V., Pellegrini, Lorenzo, Cestra, Gianluca, Butler, Margaret H., Rossman, Kent L., Serna, Daniel M., Sondek, John, Gertler, Frank B., De Camilli, Pietro

“…Tuba is a novel scaffold protein that functions to bring together dynamin with actin regulatory proteins. It is concentrated at synapses in brain and binds…”
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Role of Phosphorylation in Regulation of the Assembly of Endocytic Coat Complexes by Slepnev, Vladimir I., Ochoa, Gian-Carlo, Butler, Margaret H., Grabs, Detlev, de Camilli, Pietro

“…Clathrin-mediated endocytosis involves cycles of assembly and disassembly of clathrin coat components and their accessory proteins. Dephosphorylation of rat…”
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Phosphorylation and protonation of neighboring MiRP2 sites: function and pathophysiology of MiRP2-Kv3.4 potassium channels in periodic paralysis by Abbott, Geoffrey W, Butler, Margaret H, Goldstein, Steve A. N

“…MinK-related peptide 2 (MiRP2) and Kv3.4 subunits assemble in skeletal muscle to create subthreshold, voltage-gated potassium channels. MiRP2 acts on Kv3.4 to…”
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Ito Channels Are Octomeric Complexes with Four Subunits of Each Kv4.2 and K+ Channel-interacting Protein 2 by Kim, Leo A., Furst, Johannes, Butler, Margaret H., Xu, Shuhua, Grigorieff, Nikolaus, Goldstein, Steve A.N.

“…Mammalian voltage-gated K+ channels are assemblies of pore-forming α-subunits and modulating β-subunits. To operate correctly, Kv4 α-subunits in the heart and…”
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Mass Spectrometry Imaging of Chlorhexidine and Bacteria in a Model Wound by Hamerly, Timothy, H. Butler, Margaret, T. Fisher, Steve, K. Hilmer, Jonathan, A. James, Garth, Bothner, Brian

“…The ability to generate two-dimensional images of a wound that contains information about the distribution of bacteria overlaid with the distribution of drugs…”
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Forward Transport: 14-3-3 Binding Overcomes Retention in Endoplasmic Reticulum by Dibasic Signals by O'Kelly, Ita, Butler, Margaret H., Zilberberg, Noam, Goldstein, Steve A.N.

“…Proteins with dibasic retention motifs are subject to retrograde transport to endoplasmic reticulum (ER) by COPI-coated vesicles. As forward transport requires…”
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MiRP2 Forms Potassium Channels in Skeletal Muscle with Kv3.4 and Is Associated with Periodic Paralysis by Abbott, Geoffrey W, Butler, Margaret H, Bendahhou, Saïd, Dalakas, Marinos C, Ptacek, Louis J, Goldstein, Steve A.N

“…The subthreshold, voltage-gated potassium channel of skeletal muscle is shown to contain MinK-related peptide 2 (MiRP2) and the pore-forming subunit Kv3.4…”
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Three-Dimensional Structure of Ito: Kv4.2-KChIP2 Ion Channels by Electron Microscopy at 21 Å Resolution by Kim, Leo A, Furst, Johannes, Gutierrez, David, Butler, Margaret H, Xu, Shuhua, Goldstein, Steve AN, Grigorieff, Nikolaus

“…Regulatory KChIP2 subunits assemble with pore-forming Kv4.2 subunits in 4:4 complexes to produce native voltage-gated potassium (Kv) channels like cardiac…”
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Epsin is an EH-domain-binding protein implicated in clathrin-mediated endocytosis by De Camilli, Pietro, Chen, Hong, Fre, Silvia, Slepnev, Vladimir I, Capua, Maria Rosaria, Takei, Kohji, Butler, Margaret H, Di Fiore, Pier Paolo

“…During endocytosis, clathrin and the clathrin adaptor protein AP-2 (ref. 1), assisted by a variety of accessory factors, help to generate an invaginated bud at…”
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Proton Block and Voltage Gating Are Potassium-dependent in the Cardiac Leak Channel Kcnk3 by Lopes, Coeli M.B., Gallagher, Patrick G., Buck, Marianne E., Butler, Margaret H., Goldstein, Steve A.N.

“…Potassium leak conductances were recently revealed to exist as independent molecular entities. Here, the genomic structure, cardiac localization, and…”
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Tandem Arrangement of the Clathrin and AP-2 Binding Domains in Amphiphysin 1 and Disruption of Clathrin Coat Function by Amphiphysin Fragments Comprising These Sites by Slepnev, Vladimir I., Ochoa, Gian-Carlo, Butler, Margaret H., De Camilli, Pietro

“…Amphiphysin 1 and 2 are proteins implicated in the recycling of synaptic vesicles in nerve terminals. They interact with dynamin and synaptojanin via their…”
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Rhabdomyolysis and paraneoplastic stiff-man syndrome with amphiphysin autoimmunity by Petzold, Gabor C., Marcucci, Melissa, Butler, Margaret H., Van Landeghem, Frank K. H., Einhäupl, Karl M., Solimena, Michele, Valdueza, José M., De Camilli, Pietro

“…Stiff‐Man syndrome (SMS) is a rare disease of the central nervous system characterized by chronic muscle rigidity and autoimmunity directed against synaptic…”
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Two forms of mouse syntrophin, a 58 kd dystrophin-associated protein, differ in primary structure and tissue distribution by Adams, M E, Butler, M H, Dwyer, T M, Peters, M F, Murnane, A A, Froehner, S C

“…Syntrophin, a 58 kd extrinsic membrane protein, is concentrated at postsynaptic sites at the neuromuscular junction and may be involved in clustering…”
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Three-dimensional structure of I(to); Kv4.2-KChIP2 ion channels by electron microscopy at 21 Angstrom resolution by Kim, Leo A, Furst, Johannes, Gutierrez, David, Butler, Margaret H, Xu, Shuhua, Goldstein, Steve A N, Grigorieff, Nikolaus

“…Regulatory KChIP2 subunits assemble with pore-forming Kv4.2 subunits in 4:4 complexes to produce native voltage-gated potassium (Kv) channels like cardiac…”
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Sumoylation Silences the Plasma Membrane Leak K + Channel K2P1 by Rajan, Sindhu, Plant, Leigh D., Rabin, Michael L., Butler, Margaret H., Goldstein, Steve A.N.

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Forward Transport by O'Kelly, Ita, Butler, Margaret H., Zilberberg, Noam, Goldstein, Steve A.N.

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Three-Dimensional Structure of Ito by Kim, Leo A, Furst, Johannes, Gutierrez, David, Butler, Margaret H, Xu, Shuhua, Goldstein, Steve A.N, Grigorieff, Nikolaus

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Three-Dimensional Structure of I to: Kv4.2-KChIP2 Ion Channels by Electron Microscopy at 21 Å Resolution by Kim, Leo A, Furst, Johannes, Gutierrez, David, Butler, Margaret H, Xu, Shuhua, Goldstein, Steve A.N, Grigorieff, Nikolaus

“…Regulatory KChIP2 subunits assemble with pore-forming Kv4.2 subunits in 4:4 complexes to produce native voltage-gated potassium (Kv) channels like cardiac I to…”
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Cellular concentrations of enzymes and their substrates by Albe, K R, Butler, M H, Wright, B E

“…The activity of crude and pure enzyme preparations as well as the molecular weight of these enzymes were obtained from the literature for several organisms…”
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