Search Results - "Butler, J.Scott"

Discovering Modes of Action for Therapeutic Compounds Using a Genome-Wide Screen of Yeast Heterozygotes by Lum, Pek Yee, Armour, Christopher D., Stepaniants, Sergey B., Cavet, Guy, Wolf, Maria K., Butler, J.Scott, Hinshaw, Jerald C., Garnier, Philippe, Prestwich, Glenn D., Leonardson, Amy, Garrett-Engele, Philip, Rush, Christopher M., Bard, Martin, Schimmack, Greg, Phillips, John W., Roberts, Christopher J., Shoemaker, Daniel D.

“…Modern medicine faces the challenge of developing safer and more effective therapies to treat human diseases. Many drugs currently in use were discovered…”
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Ribosome Concentration Contributes to Discrimination against Poly(A)− mRNA during Translation Initiation in Saccharomyces cerevisiae by Proweller, Aaron, Butler, J.Scott

“…Inactivation of Saccharomyces cerevisiae poly(A) polymerase in a strain bearing the temperature-sensitive lethal pap1-1 mutation results in the synthesis of…”
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The yin and yang of the exosome by Butler, J.Scott

“…Recent studies of the eukaryotic ribosomal RNA processing pathway have identified a complex of ten riboexonucleases called the exosome that plays a central…”
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Escherichia coli protein synthesis initiation factor IF3 controls its own gene expression at the translational level in vivo by Butler, J S, Springer, M, Dondon, J, Graffe, M, Grunberg-Manago, M

“…Measurements of the relative synthesis rates of mRNAs transcribed from the gene (thrS) for threonyl-tRNA synthetase and the adjacent gene (infC) for initiation…”
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Polymerase chain reaction mapping of yeast GAL7 mRNA polyadenylation sites demonstrates that 3' end processing in vitro faithfully reproduces the 3' ends observed in vivo by Sadhale, P.P, Sapolsky, R, Davis, R.W, Butler, J.S, Platt, T

“…In general, synthetic RNA transcripts corresponding to the 3' ends of Saccharomyces cerevisiae genes appear to be accurately cleaved and polyadenylated in…”
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