Search Results - "Butler, Alex"

DQueST: dynamic questionnaire for search of clinical trials by Liu, Cong, Yuan, Chi, Butler, Alex M, Carvajal, Richard D, Li, Ziran Ryan, Ta, Casey N, Weng, Chunhua

“…Abstract Objective Information overload remains a challenge for patients seeking clinical trials. We present a novel system (DQueST) that reduces information…”
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Towards clinical data-driven eligibility criteria optimization for interventional COVID-19 clinical trials by Kim, Jae Hyun, Ta, Casey N, Liu, Cong, Sung, Cynthia, Butler, Alex M, Stewart, Latoya A, Ena, Lyudmila, Rogers, James R, Lee, Junghwan, Ostropolets, Anna, Ryan, Patrick B, Liu, Hao, Lee, Shing M, Elkind, Mitchell S V, Weng, Chunhua

“…This research aims to evaluate the impact of eligibility criteria on recruitment and observable clinical outcomes of COVID-19 clinical trials using electronic…”
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The potential role of EHR data in optimizing eligibility criteria definition for cardiovascular outcome trials by Kim, Jae Hyun, Butler, Alex M., Ta, Casey N., Sun, Yingcheng, Maurer, Mathew S., Weng, Chunhua

“…[Display omitted] Cardiovascular outcome trials (CVOTs) include patients with high risks for cardiovascular events based on specific inclusion criteria. Little…”
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Ensembles of natural language processing systems for portable phenotyping solutions by Liu, Cong, Ta, Casey N., Rogers, James R., Li, Ziran, Lee, Junghwan, Butler, Alex M., Shang, Ning, Kury, Fabricio Sampaio Peres, Wang, Liwei, Shen, Feichen, Liu, Hongfang, Ena, Lyudmila, Friedman, Carol, Weng, Chunhua

“…[Display omitted] •Ensembles of natural language processing can improve phenotypic concept recognition.•A simple majority voting-based ensemble can increase…”
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Uncovering key clinical trial features influencing recruitment by Idnay, Betina, Fang, Yilu, Butler, Alex, Moran, Joyce, Li, Ziran, Lee, Junghwan, Ta, Casey, Liu, Cong, Yuan, Chi, Chen, Huanyao, Stanley, Edward, Hripcsak, George, Larson, Elaine, Marder, Karen, Chung, Wendy, Ruotolo, Brenda, Weng, Chunhua

“…Randomized clinical trials (RCT) are the foundation for medical advances, but participant recruitment remains a persistent barrier to their success. This…”
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A knowledge base of clinical trial eligibility criteria by Liu, Hao, Chi, Yuan, Butler, Alex, Sun, Yingcheng, Weng, Chunhua

“…[Display omitted] •Eligibility criteria extracted from 352,110 clinical trials in ClinicalTrials.gov.•A unique large-scale knowledge base with computable…”
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Micromechanical Origin of Plasticity and Hysteresis in Nestlike Packings by Bhosale, Yashraj, Weiner, Nicholas, Butler, Alex, Kim, Seung Hyun, Gazzola, Mattia, King, Hunter

“…Disordered packings of unbonded, semiflexible fibers represent a class of materials spanning contexts and scales. From twig-based bird nests to unwoven…”
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No free rides: Winners and losers of the proposed Toronto Transit Commission U-Pass program by Butler, Alex, Sweet, Matthias

“…This paper explores the financial gains and losses for university students in Toronto, Ontario as a result of the U-Pass proposed by the Toronto Transit…”
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Performance of ChatGPT and Google Translate for Pediatric Discharge Instruction Translation by Brewster, Ryan C L, Gonzalez, Priscilla, Khazanchi, Rohan, Butler, Alex, Selcer, Raquel, Chu, Derrick, Aires, Barbara Pontes, Luercio, Marcella, Hron, Jonathan D

“…Patients who speak languages other than English face barriers to equitable healthcare delivery. Machine translation systems, including emerging large language…”
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The 2022 to 2023 Amoxicillin Shortage and Acute Otitis Media Treatment by Brewster, Ryan Cl, Khazanchi, Rohan, Butler, Alex, O'Meara, Daniel, Bagchi, Devika, Michelson, Kenneth A

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Center Reputation and Experience Relate to Industry Payments to Congenital Heart Disease Providers by Woo, Joyce L., Butler, Alex, Jayaram, Natalie, Karamlou, Tara, LaPar, Damien, Anderson, Brett R.

“…The Physician Payments Sunshine Act was enacted to understand financial relationships with industry that might influence provider decisions. We investigated…”
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1652. Impact of the 2022-2023 Amoxicillin Shortage on Antibiotic Prescribing for Acute Otitis Media: A Regression Discontinuity Study by Khazanchi, Rohan, Brewster, Ryan, Butler, Alex, O’Meara, Daniel, Bagchi, Devika P, Michelson, Kenneth

“…Abstract Background On October 28th, 2022, the U.S. Food and Drug Administration (FDA) announced a national shortage of amoxicillin powder for liquid…”
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Building an OMOP common data model-compliant annotated corpus for COVID-19 clinical trials by Sun, Yingcheng, Butler, Alex, Stewart, Latoya A., Liu, Hao, Yuan, Chi, Southard, Christopher T., Kim, Jae Hyun, Weng, Chunhua

“…[Display omitted] •A hierarchical data schema specifies four levels of annotation granularities.•A semi-automated annotation framework reduced effort while…”
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The COVID-19 Trial Finder by Sun, Yingcheng, Butler, Alex, Lin, Fengyang, Liu, Hao, Stewart, Latoya A, Kim, Jae Hyun, Idnay, Betina Ross S, Ge, Qingyin, Wei, Xinyi, Liu, Cong, Yuan, Chi, Weng, Chunhua

“…Abstract Clinical trials are the gold standard for generating reliable medical evidence. The biggest bottleneck in clinical trials is recruitment. To…”
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Scaling Q-switched microchip lasers for shortest pulses by Butler, Alex C., Spence, David J., Coutts, David W.

“…We evaluate the design of Q-switched microchip lasers to examine the limit of their scaling to shorter picosecond pulses. A numerical model based on the laser…”
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Chia, a large annotated corpus of clinical trial eligibility criteria by Kury, Fabrício, Butler, Alex, Yuan, Chi, Fu, Li-heng, Sun, Yingcheng, Liu, Hao, Sim, Ida, Carini, Simona, Weng, Chunhua

“…We present Chia, a novel, large annotated corpus of patient eligibility criteria extracted from 1,000 interventional, Phase IV clinical trials registered in…”
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Evaluation of Housing Affordability Among US Resident Physicians by Brewster, Ryan C L, Butler, Alex, Michelson, Catherine D, Kesselheim, Jennifer

“…This cross-sectional study evaluates the extent of housing unaffordability among US residency programs…”
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A Framework for Systematic Assessment of Clinical Trial Population Representativeness Using Electronic Health Records Data by Sun, Yingcheng, Butler, Alex, Diallo, Ibrahim, Kim, Jae Hyun, Ta, Casey, Rogers, James R., Liu, Hao, Weng, Chunhua

“…Abstract Background Clinical trials are the gold standard for generating robust medical evidence, but clinical trial results often raise generalizability…”
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Comparative effectiveness of medical concept embedding for feature engineering in phenotyping by Lee, Junghwan, Liu, Cong, Kim, Jae Hyun, Butler, Alex, Shang, Ning, Pang, Chao, Natarajan, Karthik, Ryan, Patrick, Ta, Casey, Weng, Chunhua

“…Feature engineering is a major bottleneck in phenotyping. Properly learned medical concept embeddings (MCEs) capture the semantics of medical concepts, thus…”
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Principal Investigators' Perceptions on Factors Associated with Successful Recruitment in Clinical Trials by Idnay, Betina, Butler, Alex, Fang, Yilu, Li, Ziran, Lee, Junghwan, Ta, Casey, Liu, Cong, Ruotolo, Brenda, Yuan, Chi, Chen, Huanyao, Hripcsak, George, Larson, Elaine, Weng, Chunhua

“…Participant recruitment continues to be a challenge to the success of randomized controlled trials, resulting in increased costs, extended trial timelines and…”
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