Search Results - "Butler, AA"

The arcuate nucleus as a conduit for diverse signals relevant to energy homeostasis by Cone, RD, Cowley, MA, Butler, AA, Fan, W, Marks, DL, Low, MJ

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The melanocortin system and energy balance by Butler, Andrew A.

“…The melanocortins, a family of peptides produced from the post-translational processing of pro-opiomelanocortin (POMC), regulate ingestive behavior and energy…”
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The arcuate nucleus as a conduit for diverse signals relevant to energy homeostasis by Cone, R D, Cowley, M A, Butler, A A, Fan, W, Marks, D L, Low, M J

“…Arcuate nucleus neurons are known to be responsive to a wide array of hormones and nutrients, including leptin, insulin, gonadal steroids and glucose. In…”
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A unique metabolic syndrome causes obesity in the melanocortin-3 receptor-deficient mouse by Butler, A A, Kesterson, R A, Khong, K, Cullen, M J, Pelleymounter, M A, Dekoning, J, Baetscher, M, Cone, R D

“…The central melanocortin system is critical for the long term regulation of energy homeostasis. Null mutations of the melanocortin-4 receptor (MC4-R) are…”
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Nuclear isomers in superheavy elements as stepping stones towards the island of stability by Leppänen, A.-P, Moon, S, Theisen, Ch, Leino, M, Venhart, M, Rahkila, P, Eskola, K, Sun, Y, Uusitalo, J, Eeckhaudt, S, Gray-Jones, C, Ketelhut, S, Pakarinen, J, Grahn, T, Greenlees, P. T, Darby, I. G, Nyman, M, Jones, G. D, Hessberger, F. P, Steer, A, Herzberg, R.-D, Butler, P. A, Page, R. D, Jones, P, Korten, W, Pritchard, A, Scholey, C, Julin, R, Sarén, J, Juutinen, S

“…A long-standing prediction of nuclear models is the emergence of a region of long-lived, or even stable, superheavy elements beyond the actinides. These nuclei…”
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Minireview: tissue-specific versus generalized gene targeting of the igf1 and igf1r genes and their roles in insulin-like growth factor physiology by Butler, A A, LeRoith, D

“…The insulin-like growth factors (IGF-I and IGF-II) and the IGF-I receptor are critically important for normal growth and development of the organism…”
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Ability Versus Hazard: Risk-Taking and Falls in Older People by Butler, Annie A., Lord, Stephen R., Taylor, Janet L., Fitzpatrick, Richard C.

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Control of growth by the somatropic axis: growth hormone and the insulin-like growth factors have related and independent roles by Butler, A A, Le Roith, D

“…The traditionally accepted theory has been that most of the biological effects of growth hormone (GH) are mediated by circulating (endocrine) insulin-like…”
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A Novel Porphyromonas gingivalis FeoB Plays a Role in Manganese Accumulation by Dashper, Stuart G., Butler, Catherine A., Lissel, J. Patricia, Paolini, Rita A., Hoffmann, Brigitte, Veith, Paul D., O'Brien-Simpson, Neil M., Snelgrove, Sarah L., Tsiros, John T., Reynolds, Eric C.

“…FeoB is an atypical transporter that has been shown to exclusively mediate ferrous ion transport in some bacteria. Unusually the genome of the periodontal…”
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Melanocortin-4 receptor is required for acute homeostatic responses to increased dietary fat by Cone, Roger D, Butler, Andrew A, Marks, Daniel L, Fan, Wei, Kuhn, Cynthia M, Bartolome, Maria

“…In response to moderately increased dietary fat content, melanocortin-4 receptor-null mutant (MC4R-/-) mice exhibit hyperphagia and accelerated weight gain…”
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Diet-Genotype Interactions in the Development of the Obese, Insulin-Resistant Phenotype of C57BL/6J Mice Lacking Melanocortin-3 or -4 Receptors by Sutton, Gregory M, Trevaskis, James L, Hulver, Matthew W, McMillan, Ryan P, Markward, Nathan J, Babin, M. Josephine, Meyer, Emily A, Butler, Andrew A

“…Loss of brain melanocortin receptors (Mc3rKO and Mc4rKO) causes increased adiposity and exacerbates diet-induced obesity (DIO). Little is known about how Mc3r…”
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A Role for the Endogenous Opioid β-Endorphin in Energy Homeostasis by Appleyard, Suzanne M, Hayward, Michael, Young, Juan I, Butler, Andrew A, Cone, Roger D, Rubinstein, Marcelo, Low, Malcolm J

“…Proopiomelanocortin (POMC) neurons in the hypothalamus are direct targets of the adipostatic hormone leptin and contribute to energy homeostasis by integrating…”
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Knockout Studies Defining Different Roles for Melanocortin Receptors in Energy Homeostasis by BUTLER, ANDREW A., CONE, ROGER D.

“…: Proopiomelanocortin (POMC) is expressed in the arcuate nucleus of the hypothalamus (ARC) and the commissural nucleus of the solitary tract (cNTS)…”
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The melanocortin receptors: Lessons from knockout models by Butler, A.A, Cone, R.D

“…Identifying the role of the melanocortin system in regulating energy homeostasis has relied on both genetic and pharmacological studies. The key findings…”
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Double Leptin and Melanocortin-4 Receptor Gene Mutations Have an Additive Effect on Fat Mass and Are Associated with Reduced Effects of Leptin on Weight Loss and Food Intake by Trevaskis, James L, Butler, Andrew A

“…Melanocortin-4 receptors (MC4Rs) are involved in the regulation of food intake, sympathetic nervous activity, and adrenal and thyroid function by leptin. The…”
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Differential Role of Melanocortin Receptor Subtypes in Cachexia by Marks, Daniel L, Butler, Andrew A, Turner, Renn, Brookhart, Gregor, Cone, Roger D

“…Animals and humans respond to starvation with a complex neuroendocrine response that ultimately leads to an increase in appetite, a sparing of lean body mass…”
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The Central Melanocortin System Can Directly Regulate Serum Insulin Levels by Fan, Wei, Dinulescu, Daniela M., Butler, Andrew A., Zhou, Jeanie, Marks, Daniel L., Cone, Roger D.

“…Abstract The central melanocortin system has been demonstrated to play a pivotal role in energy homeostasis. Genetic disruption of this system causes obesity…”
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Impaired Coordination of Nutrient Intake and Substrate Oxidation in Melanocortin-4 Receptor Knockout Mice by Albarado, Diana C, McClaine, Jennifer, Stephens, Jacqueline M, Mynatt, Randall L, Ye, Jianping, Bannon, Anthony W, Richards, William G, Butler, Andrew A

“…Mutations in the melanocortin-4 receptor (MC4R) are associated with obesity. The obesity syndrome observed in humans with MC4R haploinsufficiency is similar to…”
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Insulin-like growth factor-I receptor signal transduction: at the interface between physiology and cell biology by Butler, Andrew A, Yakar, Shoshana, Gewolb, Ira H, Karas, Michael, Okubo, Yumiko, LeRoith, Derek

“…The insulin-like growth factor-I receptor (IGF-IR) mediates the biological actions of IGF-I and IGF-II. The IGFs play a critical role in promoting development,…”
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Methylene Blue by Intraosseous Infusion for Methemoglobinemia by Herman, Martin I, Chyka, Peter A, Butler, Adrianne Y, Rieger, Sarah E

“…Intraosseous administration of methylene blue may be an emergency alternative to intravascular administration. A 6-week-old female infant (3 kg) presented to…”
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