Search Results - "Buth, Jessie E."
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Identification of neural oscillations and epileptiform changes in human brain organoids
Published in Nature neuroscience (01-10-2021)“…Brain organoids represent a powerful tool for studying human neurological diseases, particularly those that affect brain growth and structure. However, many…”
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Self-Organized Cerebral Organoids with Human-Specific Features Predict Effective Drugs to Combat Zika Virus Infection
Published in Cell reports (Cambridge) (10-10-2017)“…The human cerebral cortex possesses distinct structural and functional features that are not found in the lower species traditionally used to model brain…”
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25-Hydroxycholesterol Protects Host against Zika Virus Infection and Its Associated Microcephaly in a Mouse Model
Published in Immunity (Cambridge, Mass.) (21-03-2017)“…Zika virus (ZIKV) has become a public health threat due to its global transmission and link to severe congenital disorders. The host immune responses to ZIKV…”
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Foxp1 suppresses cortical angiogenesis and attenuates HIF-1alpha signaling to promote neural progenitor cell maintenance
Published in EMBO reports (14-05-2024)“…Neural progenitor cells within the cerebral cortex undergo a characteristic switch between symmetric self-renewing cell divisions early in development and…”
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TGFβ superfamily signaling regulates the state of human stem cell pluripotency and capacity to create well-structured telencephalic organoids
Published in Stem cell reports (11-10-2022)“…Telencephalic organoids generated from human pluripotent stem cells (hPSCs) are a promising system for studying the distinct features of the developing human…”
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