Search Results - "Butera, Alessio"

p53 regulates expression of nuclear envelope components in cancer cells by Panatta, Emanuele, Butera, Alessio, Celardo, Ivana, Leist, Marcel, Melino, Gerry, Amelio, Ivano

“…Nuclear organisation and architecture are essential for the maintenance of genomic integrity as well as for the epigenetic regulations and gene expression…”
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BAP1 in cancer: epigenetic stability and genome integrity by Caporali, Sabrina, Butera, Alessio, Amelio, Ivano

“…Mutations in BAP1 have been identified in a hereditary cancer predisposition syndrome and in sporadic tumours. Individuals carrying familiar BAP1 monoallelic…”
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ZNF750 represses breast cancer invasion via epigenetic control of prometastatic genes by Cassandri, Matteo, Butera, Alessio, Amelio, Ivano, Lena, Anna Maria, Montanaro, Manuela, Mauriello, Alessandro, Anemona, Lucia, Candi, Eleonora, Knight, Richard A., Agostini, Massimiliano, Melino, Gerry

“…Breast cancer is the second leading cause of cancer-related deaths among women, largely due to the progression of a significant fraction of primary tumours to…”
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Exposure of the SH-SY5Y Human Neuroblastoma Cells to 50-Hz Magnetic Field: Comparison Between Two-Dimensional (2D) and Three-Dimensional (3D) In Vitro Cultures by Consales, Claudia, Butera, Alessio, Merla, Caterina, Pasquali, Emanuela, Lopresto, Vanni, Pinto, Rosanna, Pierdomenico, Maria, Mancuso, Mariateresa, Marino, Carmela, Benassi, Barbara

“…We here characterize the response to the extremely low-frequency (ELF) magnetic field (MF, 50 Hz, 1 mT) of SH-SY5Y human neuroblastoma cells, cultured in a…”
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Deconvoluting gene and environment interactions to develop an “epigenetic score meter” of disease by Butera, Alessio, Smirnova, Lena, Ferrando‐May, Elisa, Hartung, Thomas, Brunner, Thomas, Leist, Marcel, Amelio, Ivano

“…Human health is determined both by genetics (G) and environment (E). This is clearly illustrated in groups of individuals who are exposed to the same…”
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p53-driven lipidome influences non-cell-autonomous lysophospholipids in pancreatic cancer by Butera, Alessio, Roy, Micaela, Zampieri, Carlotta, Mammarella, Eleonora, Panatta, Emanuele, Melino, Gerry, D'Alessandro, Angelo, Amelio, Ivano

“…Adaptation of the lipid metabolism participates  in cancer pathogenesis, facilitating energy storage and influencing cell fate and control of molecular…”
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The ZNF750–RAC1 axis as potential prognostic factor for breast cancer by Butera, Alessio, Cassandri, Matteo, Rugolo, Francesco, Agostini, Massimiliano, Melino, Gerry

“…The human zinc finger (C2H2-type) protein ZNF750 is a transcription factor regulated by p63 that plays a critical role in epithelial tissues homoeostasis, as…”
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Deciphering the significance of p53 mutant proteins by Butera, Alessio, Amelio, Ivano

“…Every other human cancer harbors a mutation in p53, with roughly 60–80% of these mutations linked to the acquisition of gain-of-function oncogenic properties…”
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Healthy lifestyle? or just the right genetic mutations by Butera, Alessio, Amelio, Ivano

“…The development of genomic technologies over the past decades has enabled identification of genetic variants responsible of disease; occasionally however,…”
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Epigenetic “Drivers” of Cancer by Butera, Alessio, Melino, Gerry, Amelio, Ivano

“…[Display omitted] •Alterations of the cellular epigenome can “drive” cancer pathogenesis.•Gene-environment interactions can dictate pro-tumorigenic epigenetic…”
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Metabolic regulation by p53 prevents R-loop-associated genomic instability by Panatta, Emanuele, Butera, Alessio, Mammarella, Eleonora, Pitolli, Consuelo, Mauriello, Alessandro, Leist, Marcel, Knight, Richard A., Melino, Gerry, Amelio, Ivano

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Fifty-Hertz Magnetic Field Affects the Epigenetic Modulation of the miR-34b/c in Neuronal Cells by Consales, Claudia, Cirotti, Claudia, Filomeni, Giuseppe, Panatta, Martina, Butera, Alessio, Merla, Caterina, Lopresto, Vanni, Pinto, Rosanna, Marino, Carmela, Benassi, Barbara

“…The exposure to extremely low-frequency magnetic fields (ELF-MFs) has been associated to increased risk of neurodegenerative diseases, although the underlying…”
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50‐Hz MF does not affect global DNA methylation of SH‐SY5Y cells treated with the neurotoxin MPP by Benassi, Barbara, Santangeli, Stefania, Merla, Caterina, Tarantini, Letizia, Bollati, Valentina, Butera, Alessio, Marino, Carmela, Consales, Claudia

“…Exposure to extremely low frequency magnetic fields (ELF‐MFs) has been associated with an increased risk of neurodegenerative disorders. The underlying…”
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50-Hz magnetic field impairs the expression of iron-related genes in the in vitro SOD1 G93A model of amyotrophic lateral sclerosis by Consales, Claudia, Panatta, Martina, Butera, Alessio, Filomeni, Giuseppe, Merla, Caterina, Carrì, Maria Teresa, Marino, Carmela, Benassi, Barbara

“…We characterized the response to the extremely low frequency magnetic field (ELF-MF) in an in vitro model of familial Amyotrophic Lateral Sclerosis (fALS),…”
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50-Hz magnetic field impairs the expression of iron-related genes in the in vitro SOD1G93A model of amyotrophic lateral sclerosis by Consales, Claudia, Panatta, Martina, Butera, Alessio, Filomeni, Giuseppe, Merla, Caterina, Carrì, Maria Teresa, Marino, Carmela, Benassi, Barbara

“…Purpose: We characterized the response to the extremely low frequency magnetic field (ELF-MF) in an in vitro model of familial Amyotrophic Lateral Sclerosis…”
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ZFP750 affects the cutaneous barrier through regulating lipid metabolism by Butera, Alessio, Agostini, Massimiliano, Cassandri, Matteo, De Nicola, Francesca, Fanciulli, Maurizio, D'Ambrosio, Lorenzo, Falasca, Laura, Nardacci, Roberta, Wang, Lu, Piacentini, Mauro, Knight, Richard A, Jia, Wei, Sun, Qiang, Shi, Yufang, Wang, Ying, Candi, Eleonora, Melino, Gerry

“…An essential function of the epidermis is to provide a physical barrier that prevents the loss of water. Essential mediators of this barrier function include…”
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