Search Results - "Butcher, Rebecca"

Small-molecule pheromones and hormones controlling nematode development by Butcher, Rebecca A

“…The existence of small-molecule signals that influence development in Caenorhabditis elegans has been known for several decades, but only in recent years have…”
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Natural products as chemical tools to dissect complex biology in C. elegans by Butcher, Rebecca A

“…The search for novel pheromones, hormones, and other types of natural products in the nematode Caenorhabditis elegans has accelerated over the last 10–15…”
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Warhead assembly in a lethal pathogen by Abraham, Elijah, Butcher, Rebecca A.

“…Malleicyprols are highly reactive polyketides responsible for virulence in some pathogenic bacteria. Now, the enzyme that constructs the cyclopropanol warhead…”
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Decoding chemical communication in nematodes by Butcher, Rebecca A

“…The nematode Caenorhabditis elegans produces tens, if not hundreds, of different ascarosides as pheromones to communicate with other members of its species…”
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Chemical Signals Synchronize the Life Cycles of a Plant-Parasitic Nematode and Its Vector Beetle by Zhao, Lilin, Zhang, Shuai, Wei, Wei, Hao, Haijun, Zhang, Bin, Butcher, Rebecca A., Sun, Jianghua

“…The pinewood nematode Bursaphelenchus xylophilus has caused severe damage to pine forests in large parts of the world [1–4]. Dispersal of this plant-parasitic…”
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Interspecific communication between pinewood nematode, its insect vector, and associated microbes by Zhao, Lilin, Mota, Manuel, Vieira, Paulo, Butcher, Rebecca A, Sun, Jianghua

“…Highlights • The pinewood nematode (PWN) forms a symbiotic partnership with its insect vector and associated microbes. • Chemical signals produced by…”
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Identification of a dTDP-rhamnose biosynthetic pathway that oscillates with the molting cycle in Caenorhabditis elegans by Feng, Likui, Shou, Qingyao, Butcher, Rebecca A

“…L-Rhamnose is a common component of cell-wall polysaccharides, glycoproteins and some natural products in bacteria and plants, but is rare in fungi and…”
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IL-17 is a neuromodulator of Caenorhabditis elegans sensory responses by Chen, Changchun, Itakura, Eisuke, Nelson, Geoffrey M., Sheng, Ming, Laurent, Patrick, Fenk, Lorenz A., Butcher, Rebecca A., Hegde, Ramanujan S., de Bono, Mario

“…Interleukin-17 (IL-17) is a major pro-inflammatory cytokine: it mediates responses to pathogens or tissue damage, and drives autoimmune diseases. Little is…”
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Neuromodulatory State and Sex Specify Alternative Behaviors through Antagonistic Synaptic Pathways in C. elegans by Jang, Heeun, Kim, Kyuhyung, Neal, Scott J., Macosko, Evan, Kim, Dongshin, Butcher, Rebecca A., Zeiger, Danna M., Bargmann, Cornelia I., Sengupta, Piali

“…Pheromone responses are highly context dependent. For example, the C. elegans pheromone ascaroside C9 (ascr#3) is repulsive to wild-type hermaphrodites,…”
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Small-molecule pheromones that control dauer development in Caenorhabditis elegans by Clardy, Jon, Butcher, Rebecca A, Fujita, Masaki, Schroeder, Frank C

“…In response to high population density or low food supply, the nematode Caenorhabditis elegans enters an alternative larval stage, known as the dauer, that can…”
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Ascarosides coordinate the dispersal of a plant-parasitic nematode with the metamorphosis of its vector beetle by Zhao, Lilin, Zhang, Xinxing, Wei, Yanan, Zhou, Jiao, Zhang, Wei, Qin, Peijun, Chinta, Satya, Kong, Xiangbo, Liu, Yunpeng, Yu, Haiying, Hu, Songnian, Zou, Zhen, Butcher, Rebecca A., Sun, Jianghua

“…Insect vectors are required for the transmission of many species of parasitic nematodes, but the mechanisms by which the vectors and nematodes coordinate their…”
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CREB mediates the C. elegans dauer polyphenism through direct and cell-autonomous regulation of TGF-β expression by Park, JiSoo, Oh, Hyekyoung, Kim, Do-Young, Cheon, YongJin, Park, Yeon-Ji, Hwang, Hyeonjeong, Neal, Scott J., Dar, Abdul Rouf, Butcher, Rebecca A., Sengupta, Piali, Kim, Dae-Won, Kim, Kyuhyung

“…Animals can adapt to dynamic environmental conditions by modulating their developmental programs. Understanding the genetic architecture and molecular…”
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Parallel evolution of domesticated Caenorhabditis species targets pheromone receptor genes by McGrath, Patrick T., Xu, Yifan, Ailion, Michael, Garrison, Jennifer L., Butcher, Rebecca A., Bargmann, Cornelia I.

“…When the worms turned If we could return the planet to ancestral conditions, asked the late Stephen Jay Gould, would we get a replay of the same evolutionary…”
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A sexually conditioned switch of chemosensory behavior in C. elegans by Sakai, Naoko, Iwata, Ryo, Yokoi, Saori, Butcher, Rebecca A, Clardy, Jon, Tomioka, Masahiro, Iino, Yuichi

“…In sexually reproducing animals, mating is essential for transmitting genetic information to the next generation and therefore animals have evolved mechanisms…”
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Mapping the biosynthetic pathway of a hybrid polyketide-nonribosomal peptide in a metazoan by Feng, Likui, Gordon, Matthew T., Liu, Ying, Basso, Kari B., Butcher, Rebecca A.

“…Polyketide synthase (PKS) and nonribosomal peptide synthetase (NRPS) hybrid systems typically use complex protein-protein interactions to facilitate direct…”
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Influence of symbiotic and non-symbiotic bacteria on pheromone production in Steinernema nematodes (Nematoda, Steinernematidae) by Roder, Alexandra C, Wang, Yuting, Butcher, Rebecca A, Stock, S Patricia

“…In this study, we assessed the effect of symbiotic (cognate and non-cognate) and non-symbiotic bacteria on ascaroside production of first-generation adults in…”
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Pathogenic bacteria modulate pheromone response to promote mating by Wu, Taihong, Ge, Minghai, Wu, Min, Duan, Fengyun, Liang, Jingting, Chen, Maoting, Gracida, Xicotencatl, Liu, He, Yang, Wenxing, Dar, Abdul Rouf, Li, Chengyin, Butcher, Rebecca A., Saltzman, Arneet L., Zhang, Yun

“…Pathogens generate ubiquitous selective pressures and host–pathogen interactions alter social behaviours in many animals 1 – 4 . However, very little is known…”
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Tryptophan Metabolism in Caenorhabditis elegans Links Aggregation Behavior to Nutritional Status by Zhou, Yue, Zhang, Xinxing, Butcher, Rebecca A

“…Caenorhabditis elegans uses aggregation pheromones to communicate its nutritional status and recruit fellow members of its species to food sources. These…”
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A hub-and-spoke circuit drives pheromone attraction and social behaviour in C. elegans by Macosko, Evan Z, Bargmann, Cornelia I, Feinberg, Evan H, Pokala, Navin, Butcher, Rebecca A, Chalasani, Sreekanth H, Clardy, Jon

“…Innate social behaviours emerge from neuronal circuits that interpret sensory information on the basis of an individual's own genotype, sex and experience. The…”
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Acyl-CoA oxidase complexes control the chemical message produced by Caenorhabditis elegans by Zhang, Xinxing, Feng, Likui, Chinta, Satya, Singh, Prashant, Wang, Yuting, Nunnery, Joshawna K, Butcher, Rebecca A

“…Caenorhabditis elegans uses ascaroside pheromones to induce development of the stress-resistant dauer larval stage and to coordinate various behaviors…”
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