Search Results - "Butcher, Lindsay D"

Oxidative Stress Resulting From Helicobacter pylori Infection Contributes to Gastric Carcinogenesis by Butcher, Lindsay D, den Hartog, Gerco, Ernst, Peter B, Crowe, Sheila E

“…Helicobacter pylori is a gram-negative, microaerophilic bacterium that infects the stomach and can lead to, among other disorders, the development of gastric…”
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Regulation of Rac1 and Reactive Oxygen Species Production in Response to Infection of Gastrointestinal Epithelia by den Hartog, Gerco, Chattopadhyay, Ranajoy, Ablack, Amber, Hall, Emily H, Butcher, Lindsay D, Bhattacharyya, Asima, Eckmann, Lars, Harris, Paul R, Das, Soumita, Ernst, Peter B, Crowe, Sheila E

“…Generation of reactive oxygen species (ROS) during infection is an immediate host defense leading to microbial killing. APE1 is a multifunctional protein…”
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Prohibitin 1 modulates mitochondrial stress-related autophagy in human colonic epithelial cells by Kathiria, Arwa S, Butcher, Lindsay D, Feagins, Linda A, Souza, Rhonda F, Boland, C Richard, Theiss, Arianne L

“…Autophagy is an adaptive response to extracellular and intracellular stress by which cytoplasmic components and organelles, including damaged mitochondria, are…”
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Apurinic/Apyrimidinic Endonuclease 1 Restricts the Internalization of Bacteria Into Human Intestinal Epithelial Cells Through the Inhibition of Rac1 by den Hartog, Gerco, Butcher, Lindsay D, Ablack, Amber L, Pace, Laura A, Ablack, Jailal N G, Xiong, Richard, Das, Soumita, Stappenbeck, Thaddeus S, Eckmann, Lars, Ernst, Peter B, Crowe, Sheila E

“…Pathogenic intestinal bacteria lead to significant disease in humans. Here we investigated the role of the multifunctional protein, Apurinic/apyrimidinic…”
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Antitumor Activity of an Oncolytic Adenoviral-CD40 Ligand (CD154) Transgene Construct in Human Breast Cancer Cells by GOMES, Erica M, RODRIGUES, Margret S, TONG, Alex W, PHADKE, Anagha P, BUTCHER, Lindsay D, STARLING, Cherry, CHEN, Salina, DONGKUN CHANG, HERNANDEZ-ALCOCEBA, Ruben, NEWMAN, Joseph T, STONE, Marvin J

“…Purpose: CD40 ligand (CD40L, CD154) plays a central role in immunoregulation and also directly modulates epithelial cell growth and differentiation. We…”
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Developmental Immaturity of Siglec Receptor Expression on Neonatal Alveolar Macrophages Predisposes to Severe Group B Streptococcal Infection by Lund, Sean J., Patras, Kathryn A., Kimmey, Jacqueline M., Yamamura, Asami, Butcher, Lindsay D., Del Rosario, Pamela G.B., Hernandez, Gilberto E., McCoy, Alyssa M., Lakhdari, Omar, Nizet, Victor, Prince, Lawrence S.

“…Streptococcus agalactiae (Group B Streptococcus, GBS) is the most common neonatal pathogen. However, the cellular and molecular mechanisms for neonatal…”
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Growth Inhibition of Human Multiple Myeloma Cells by an Oncolytic Adenovirus Carrying the CD40 Ligand Transgene by FERNANDES, Margret S, GOMES, Erica M, BUTCHER, Lindsay D, HERNANDEZ-ALCOCEBA, Reuben, DONGKUN CHANG, KANSOPON, Joe, NEWMAN, Joseph, STONE, Marvin J, TONG, Alex W

“…Purpose: The growth-inhibitory activity of recombinant CD40 ligand (CD40L) is well documented in human multiple myeloma (MM). We examined MM-targeted delivery…”
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Sp3 is essential for normal lung morphogenesis and cell cycle progression during mouse embryonic development by McCoy, Alyssa M, Lakhdari, Omar, Shome, Sayane, Caoili, Kaitlin, Hernandez, Gilberto E, Aghaeepour, Nima, Butcher, Lindsay D, Fisch, Kathleen, Prince, Lawrence S

“…Members of the Sp family of transcription factors regulate gene expression via binding GC boxes within promoter regions. Unlike Sp1, which stimulates…”
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The Lung Microenvironment Instructs Gene Transcription in Neonatal and Adult Alveolar Macrophages by Honda, Asami, Hoeksema, Marten A, Sakai, Mashito, Lund, Sean J, Lakhdari, Omar, Butcher, Lindsay D, Rambaldo, Tara C, Sekiya, Neal M, Nasamran, Chanond A, Fisch, Kathleen M, Sajti, Eniko, Glass, Christopher K, Prince, Lawrence S

“…Immaturity of alveolar macrophages (AMs) around birth contributes to the susceptibility of newborns to lung disease. However, the molecular features…”
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A Novel Hypomorphic Apex1 Mouse Model Implicates Apurinic/Apyrimidinic Endonuclease 1 in Oxidative DNA Damage Repair in Gastric Epithelial Cells by Rios-Covian, David, Butcher, Lindsay D, Ablack, Amber L, den Hartog, Gerco, Matsubara, Mason T, Ly, Hong, Oates, Andrew W, Xu, Guorong, Fisch, Kathleen M, Ahrens, Eric T, Toden, Shusuke, Brown, Corrie C, Kim, Kenneth, Le, Dzung, Eckmann, Lars, Dhar, Bithika, Izumi, Tadahide, Ernst, Peter B, Crowe, Sheila E

“…Though best known for its role in oxidative DNA damage repair, apurinic/apyrimidinic endonuclease 1 (APE1) is a multifunctional protein that regulates multiple…”
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973 Human Intestinal Epithelial Host Defense Against Pathogenic Bacterial Infections is Regulated by AP Endonuclease 1 (APE1/Ref-1) by den Hartog, Gerco, Ablack, Amber, Butcher, Lindsay D, Pace, Laura A, Das, Soumita, Ernst, Peter, Crowe, Sheila E

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Sa1974 Immune Response to the T Antigen of JC Virus in Patients With Colorectal Neoplasia Compared to Those Without by Butcher, Lindsay D, Garcia, Melissa, Ueno, Hideki, Goel, Ajay, Boland, C. Richard

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5 Regulation of Rac1 and Reactive Oxygen Species Production in Response to Helicobacter pylori Infection of Gastric Epithelium by Butcher, Lindsay D, den Hartog, Gerco, Chattopadhyay, Ranajoy, Ablack, Amber, Pace, Laura A, Harris, Paul R, Das, Soumita, Ernst, Peter, Crowe, Sheila E

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Immune response to JC virus T antigen in patients with and without colorectal neoplasia by Butcher, Lindsay D, Garcia, Melissa, Arnold, Mildred, Ueno, Hideki, Goel, Ajay, Boland, C Richard

“…JC virus (JCV) is a polyomavirus that infects approximately 75% of the population and encodes a T antigen (T-Ag) gene, which is oncogenic and inactivates the…”
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320 Prohibitin 1 Modulates Mitochondrial Stress-Related Autophagy in Human Colonic Epithelial Cells by Kathiria, Arwa S, Butcher, Lindsay D, Feagins, Linda A, Souza, Rhonda F, Boland, Clement R, Theiss, Arianne L

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Role of Apurinic/Apyrimidinic Endonuclease 1 in Modulating Rac1 and Nox1 in Gastrointestinal Epithelial Responses to Microbial Infection by Hartog, Gerco den, Ablack, Amber L, Butcher, Lindsay D, Fox, Sarah, Ablack, Jailal N.G, Marchelletta, Ronald R, Das, Soumita, Ernst, Peter B, Crowe, Sheila E

“…Apurinic/apyrimidinic endonuclease (APE1)/Redox activating factor 1 (Ref-1) is a multifunctional protein that regulates gene transcription and cell death. We…”
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Distinct Changes in the Chromatin Landscape Regulate Maturation of the Alveolar Macrophage Immune Response In Vivo by Yamamura, Asami, Hoeksema, Marten A., Sakai, Mashito, Lund, Sean J., Butcher, Lindsay D., Lakhdari, Omar, Oppong-Nonterah, Gertrude O., Sajti, Eniko, Glass, Christopher K., Prince, Lawrence S.

“…Alveolar macrophages (AMs) perform specialized functions in the lung including protection against inhaled microbes and repair following injury. Neonates are…”
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Developmental immaturity of sialic acid recognition mediates neonatal susceptibility to GBS pneumonia by Lund, Sean J, Patras, Kathryn A, Kimmey, Jacqueline M, Yamamura, Asami, Butcher, Lindsay D, Del Rosario, Pamela G B, Hernandez, Gilberto E, McCoy, Alyssa M, Lakhdari, Omar, Nizet, Victor, Prince, Lawrence S

“…Group B Streptococcus (GBS) is a major neonatal pathogen but rarely causes disease in adults. We previously showed in mice that GBS escapes killing in the…”
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149 - Gastrointestinal Microbes Enhance the Accumulation of Reactive Oxygen Species (ROS) and Dna Damage that are Regulated by Apurinic/Apyrimidinic Endonuclease 1 (APE1) by Butcher, Lindsay D., den Hartog, Gerco, Ablack, Amber, Matsubara, Mason, Ablack, Jailal, Thron, Taren, Mazmanian, Sarkis, Eckmann, Lars, Ernst, Peter, Izumi, Tadahide, Crowe, Sheila E.

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Regulation of Rac1 and Reactive Oxygen Species Production in Response to Infection of Gastrointestinal Epithelia: e1005382 by Hartog, Gerco den, Chattopadhyay, Ranajoy, Ablack, Amber, Hall, Emily H, Butcher, Lindsay D, Bhattacharyya, Asima, Eckmann, Lars, Harris, Paul R, Das, Soumita, Ernst, Peter B, Crowe, Sheila E

“…Generation of reactive oxygen species (ROS) during infection is an immediate host defense leading to microbial killing. APE1 is a multifunctional protein…”
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